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JTO Clinical and Research Reports

JTO Clinical and Research Reports is the official open access journal of the International Association for the Study of Lung Cancer. It complements the Journal of Thoracic Oncology by offering a gold open access publication option and particularly publishes Phase I trials, well performed single-arm phase II trials, subset analyses of published trials, impactful retrospective studies, database analysis, large institutional series, high-quality case reports, region-specific clinical trials, subspecialty thoracic oncology studies, and selected high-quality meeting reports.

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Subject Oncology, Respiratory System
Impact Factor 3.5
Quartile Q2
Open Access Type Open
eISSN 2666-3643
Invitation Only No
Cost Range Article Publishing Charge (APC): USD 2,000 (excluding taxes)

Submission Instructions

JTO Clinical and Research Reports accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Original Articles must include a structured abstract. The abstract must not exceed 250 words. The abstract must be structured. The abstract must use the headings Introduction or Hypothesis, Methods, Results, and Conclusions.
Manuscript The manuscript must contain 4,000 words of text. The manuscript must be organized under the headings Introduction, Materials and Methods, Results, and Discussion. The manuscript must include three to five keywords and, if generative AI or AI-assisted technologies were used in writing, a disclosure statement before the references under the heading 'Declaration of Generative AI and AI-assisted technologies in the writing process'.
References The manuscript may include up to 50 references. References must be cited with consecutive superscript Arabic numerals and listed in numbered order of appearance. Journal names in references must be abbreviated according to the List of Title Word Abbreviations.
Figures & Tables The manuscript may include up to 6 tables and/or figures. Figures must be submitted as separate files with captions provided separately, and tables must be submitted as editable text. Figures and tables must be numbered consecutively in the order they are cited in the text.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Introduction or Hypothesis, Methods, Results, and Conclusions.
Manuscript Manuscript must be no longer than 4000 words. Manuscript must be organized under the headings Introduction, Materials and Methods, Results, and Discussion. Manuscript must include three to five keywords and a Declaration of Generative AI and AI-assisted technologies in the writing process before the references if such tools were used.
References References must not exceed 75. References must be cited as consecutive superscript Arabic numerals and listed in the order of appearance in the text.
Figures & Tables The article may include up to 6 tables and/or figures. Figures must be submitted as separate files with captions provided separately, and tables must be submitted as editable text.
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Brief Reports

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required for Brief Reports. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Introduction or Hypothesis, Methods, Results, and Conclusions.
Manuscript Manuscript must not exceed 1500 words. Manuscript must be organized under the four main headings Introduction, Materials and Methods, Results, and Discussion, and the title must include "Brief Report:". Manuscript must include three to five keywords and a declaration of generative AI and AI-assisted technologies in the writing process before the references if such tools were used.
References References must not exceed 15. References must be cited as consecutive superscript Arabic numerals in the text and listed in numbered order of appearance, with journal names abbreviated according to the List of Title Word Abbreviations.
Figures & Tables Brief Reports may include up to 3 tables and/or figures. Figures must be submitted as separate files with captions provided separately, and tables must be submitted as editable text.
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Case Reports

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and may be structured or unstructured. Abstract must not exceed 250 words. Abstract may be structured or unstructured. Abstract must include an introduction on what is unique about the case and its contribution to the literature, the patient's main concerns and important clinical findings, the primary diagnoses interventions and outcomes, and a conclusion with one or more take-away lessons.
Manuscript Manuscript must be 1000 words or less. Manuscript must include Introduction, Case Presentation, Discussion, and Conclusion sections. Manuscript must include 2 to 5 keywords including "case report," a conflict of interest disclosure statement, a short acknowledgement section mentioning funding support if applicable, a timeline figure or table, and de-identified patient-specific case details covering history, findings, diagnostics, interventions, outcomes, follow-up, adherence or tolerability, adverse events, and discussion of strengths, limitations, relevant literature, and rationale for conclusions.
References References must not exceed 5. References must be cited in the text using consecutive superscript Arabic numerals and listed in numbered order of appearance.
Figures & Tables Figures and tables may total no more than 3. Each illustration must be submitted as a separate file and captions for illustrations must be provided separately. Case Reports should include images and or photographs supporting the case, and the required timeline must be presented as a figure or table.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Letters to the Editor must contain no more than 500 words. Letters to the Editor must be short, concise communications commenting on a recently published article in the journal or on a controversial current issue of concern to the readership. Letters to the Editor must be accompanied by a statement of potential sources of conflict of interest.
References Letters to the Editor must contain no more than 5 references, including a reference to the article in question. References must be cited in the text as consecutive superscript Arabic numerals and listed in numerical order of appearance.
Figures & Tables Figures & Tables requirements are not specified.
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Recent Publications

Dacomitinib with or without dose titration in treatment naïve advanced EGFR mutated NSCLC – primary analysis of the ATORG-003 phase 2 trial

Aaron C. Tan, Tae Min Kim, Siqin Zhou, Yueh Ni Lim, Gwo Fuang Ho, Lye Mun Tho, Thanyanan Baisamut, Naiyarat Prasongsook, Suee Lee, Sze Huey Tan, Dong-Wan Kim, Tony Mok, Daniel S.W. Tan, Herbert H. Loong

10.1016/j.jtocrr.2026.101027
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Prophylactic Cranial Irradiation and Survival in Limited-Stage Small Cell Lung Cancer: A Multicenter Real-World Analysis from the Canadian Small Cell Lung Cancer Database (CASCADE)

Abdul Hadee Lone, Xiang Y. Ye, Luna Jia Zhan, Haechan Yang, Victoria Smyth, Riham H. Abdelaziz, Stephanie Snow, Sofia Genta, Sara Kuruvilla, Jason Agulnik, Vishal Navani, Cheryl Ho, David Dawe, Paul Wheatley-Price, Sara Moore, Geoffrey Liu, Benjamin H. Lok

10.1016/j.jtocrr.2026.101030
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Development and Characterization of a Patient-Derived KIF5B-RET Fusion Lung Adenocarcinoma Cell Line for Subcutaneous and Central Nervous System Tumor Models in Immunodeficient Mice

Akihiro Nishiyama, Shigeki Sato, Hiroyuki Sakaguchi, Hiroshi Kotani, Kaname Yamashita, Koushiro Ohtsubo, Shigeki Nanjo, Seiji Yano, Keishi Mizuguchi, Hiroko Ikeda, Makiko Yamaguchi, Tamotsu Ishizuka, Satoko Baba, Kengo Takeuchi, Shinji Takeuchi

10.1016/j.jtocrr.2026.101026
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Continued Cemiplimab Beyond Progression With Addition of Chemotherapy in Patients With Advanced NSCLC With PD-L1 Expression of 50% or Higher: 5-Year Follow-Up From EMPOWER-Lung 1

Marina Chiara Garassino, Ana Baramidze, Saadettin Kilickap, Ahmet Sezer, Mustafa Özgüroğlu, Mahmut Gumus, Igor Bondarenko, Miranda Gogishvili, Marina Nechaeva, Michael Schenker, Irfan Cicin, Gwo Fuang Ho, Yaroslav Kulyaba, Kasimova Zyuhal, Roxana-Ioana Scheusan, Xue Jia, Debra A.G. McIntyre, Stefanie Chua, Manika Kaul, Javier Perez, Israel Lowy, Frank Seebach, Eric Kim, Heather Magnan, Jean-Francois Pouliot

10.1016/j.jtocrr.2026.101029
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RATIONALE-303: Long-Term Outcomes of Tislelizumab in Previously Treated Advanced/Metastatic NSCLC

Pedro de Marchi, Yun Fan, Zhiyong Ma, Yan Wang, Yuanyuan Bao, Wenjuan Zheng, Kirsha Naicker, Caicun Zhou

10.1016/j.jtocrr.2026.101028
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Frequently asked questions

How long does it take to publish?

9 days submission to first decision; 47 days submission to decision after review; 111 days submission to acceptance; 6 days acceptance to online publication.

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What are the publication costs?

Article Publishing Charge (APC): USD 2,000 (excluding taxes).

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Research Topics

Lung Cancer Treatments and Mutations Lung Cancer Research Studies Lung Cancer Diagnosis and Treatment Cancer Immunotherapy and Biomarkers Cancer Genomics and Diagnostics Colorectal Cancer Treatments and Studies Neuroendocrine Tumor Research Advances Gastric Cancer Management and Outcomes Radiomics and Machine Learning in Medical Imaging Occupational and environmental lung diseases Global Cancer Incidence and Screening HER2/EGFR in Cancer Research PI3K/AKT/mTOR signaling in cancer Pancreatic and Hepatic Oncology Research Myasthenia Gravis and Thymoma Genetic factors in colorectal cancer Brain Metastases and Treatment Pleural and Pulmonary Diseases Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis Chronic Lymphocytic Leukemia Research Cancer therapeutics and mechanisms Colorectal and Anal Carcinomas Peptidase Inhibition and Analysis Neuroblastoma Research and Treatments Esophageal Cancer Research and Treatment

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