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Annual Review Of Immunology

Annual Review of Immunology focuses on basic immune mechanisms and the molecular basis of immune diseases in humans. Topics include innate and adaptive immunity, immune cell development and differentiation, immune control of pathogens and cancer, and human immunodeficiency and autoimmune diseases.

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Subject Immunology
Impact Factor 33.3
Quartile Q1
Open Access Type Closed
ISSN 0732-0582
eISSN 1545-3278
Invitation Only Yes
Cost Range Color figures are printed at no cost to authors.

Submission Instructions

Annual Review Of Immunology is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 150 words.
Manuscript Manuscript length must follow the guidelines in the invitation letter. Review Articles should present current understanding of the topic, place it in historical context, identify remaining major questions and likely future research directions, and outline practical applications and broader societal significance. Manuscript may include up to 6 keywords, up to 8 Summary Points, up to 8 Future Issues, up to 20 Terms and Definitions entries, up to 10 reference annotations, up to 10 Related Resources items, and AI use must be disclosed in the Acknowledgments and where pertinent in the article.
References References must be listed and numbered in order of appearance, include article or chapter titles, use the first author's surname followed by et al. for in-text citations with three or more authors, and all cited references must exist and be cited in the text, figure captions, or tables.
Figures & Tables Figures must be submitted as separate files rather than embedded in the text, and tables must be placed at the end of the article after the Literature Cited section or submitted together in a separate editable file. Each figure must have a clearly labeled descriptive caption, be numbered consecutively and called out in the text, and reused figures in Review Articles require permission before submission with source credit in the caption.
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Invited Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 150 words.
Manuscript Manuscript length must adhere to the guidelines presented in the invitation letter. Manuscript must be arranged in the order of title page, text, literature cited, article components, figure captions, tables, and figures. Manuscript may include up to 6 keywords, up to 20 Terms and Definitions entries of no more than 20 words each, up to 8 Summary Points, up to 8 Future Issues, up to 10 reference annotations of no more than 15 words each, up to 10 Related Resources entries, and sidebars of 50 to 200 words, and any AI use must be disclosed in the Acknowledgments and where pertinent in the article.
References References must be numbered and listed in order of appearance, include article or chapter titles, list all authors if there are six or fewer or the first five followed by et al. if there are seven or more, and in-text citations for works with three or more authors must use the first author's surname followed by et al.
Figures & Tables Figures must be submitted as separate files and not integrated within the text, while tables must be placed at the end of the article after the Literature Cited section or submitted together in a separate editable file. Each figure must have a clearly labeled descriptive caption, and all tables and figures must be called out in the text.
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Meta-Analysis

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 150 words.
Manuscript Manuscript must adhere to the length guidelines presented in the invitation letter. Manuscript may include up to 6 keywords, and any AI use in preparation must be disclosed in the Acknowledgments and where pertinent in the article.
References References must be numbered and cited in numerical sequence, with all cited items listed in the Literature Cited and references with seven or more authors shortened to the first five authors followed by et al.
Figures & Tables Figures must be uploaded as separate files rather than embedded in the text, and tables must be placed at the end of the article after the Literature Cited or submitted together in a separate editable file. Each figure must have a clearly labeled descriptive caption, and all tables and figures must be called out in the text.
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Recent Publications

B Cell Selection in Antibody Production: Affinity Rules, but Diversity Matters

Isaak Quast, David M. Tarlinton

10.1146/annurev-immunol-082323-031320
View Publication

γδ T Cells for Cancer Immunotherapy: Unconventional Players Take the Spotlight

Georgia Stevens, Rafael Blanco-Domínguez, Sofia Mensurado, Bruno Silva-Santos

10.1146/annurev-immunol-083024-024653
View Publication

T Cell Receptor Signaling and Immune Tolerance: From Autoimmunity to Cancer Immunity

Atsushi Tanaka, Shimon Sakaguchi

10.1146/annurev-immunol-082724-025403
View Publication

Immune Niches in Cancer

Nadine Slingerland, Eline Runderkamp, Daniela S. Thommen

10.1146/annurev-immunol-082724-123843
View Publication

The Molecular Logic of Immunoglobulin Heavy Chain Class Switch Recombination

William T. Yewdell, Keith Conrad Fernandez, Stephanie M. Downs-Canner, Jayanta Chaudhuri

10.1146/annurev-immunol-082323-121803
View Publication

Frequently asked questions

How long does it take to publish?

Articles may be published first as Reviews in Advance before final publication. No fixed first-decision, acceptance, or publication timeframe is stated.

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What are the publication costs?

Annual Reviews journals operate under a Subscribe to Open model. Final articles are open under CC BY-NC-ND 4.0 if the subscription threshold is met; otherwise they remain behind a paywall.

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Research Topics

Immune Cell Function and Interaction T-cell and B-cell Immunology Immunotherapy and Immune Responses Monoclonal and Polyclonal Antibodies Research Immune Response and Inflammation CAR-T cell therapy research Immunodeficiency and Autoimmune Disorders IL-33, ST2, and ILC Pathways Diabetes and associated disorders Cancer Immunotherapy and Biomarkers Glycosylation and Glycoproteins Research interferon and immune responses Cytokine Signaling Pathways and Interactions Cell Adhesion Molecules Research HIV Research and Treatment Cytomegalovirus and herpesvirus research Asthma and respiratory diseases Immune cells in cancer T-cell and Retrovirus Studies vaccines and immunoinformatics approaches Inflammasome and immune disorders Gut microbiota and health Neuroinflammation and Neurodegeneration Mechanisms NF-κB Signaling Pathways Galectins and Cancer Biology

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