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Archives Of Toxicology

Archives of Toxicology is a journal covering advancements in toxicology, emphasizing mechanisms of toxicity at the molecular level, progress in toxicology in humans and experimental animals, and new insights into analysis, toxicokinetics, and forensic toxicology. The journal features review articles of general interest to toxicologists and welcomes Short Communications, Review Articles, Original Articles, and Commentaries.

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Subject Toxicology
Impact Factor 6.9
Quartile Q1
Open Access Type Hybrid
ISSN 0340-5761
eISSN 1432-0738
Invitation Only No
Cost Range Open access APC: £3990.00 GBP / $5990.00 USD / €4690.00 EUR; subscription publishing: no APC.

Submission Instructions

Archives Of Toxicology accepts the following article types. Click on an article type to view submission instructions.

Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and must be 150 to 250 words. Abstract must be 150 to 250 words.
Manuscript Review Articles must not exceed 20 printed pages. Manuscript must include 4 to 6 keywords, a statement of responsibility specifying each author's contribution, a disclosure statement, a Declarations section before the references, and documentation of any large language model use in a suitable part of the manuscript.
References References must be cited in the text by name and year in parentheses. Reference list entries must include only cited published or accepted works and must be alphabetized by the last name of the first author.
Figures & Tables Figures should be embedded within the manuscript text unless large file size prevents this, in which case they should be submitted separately. Tables and figures must be numbered in Arabic numerals, cited in consecutive numerical order, and accompanied by captions, with figure captions provided in the manuscript text file.
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Original Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required and must be 150 to 250 words. Abstract must be 150 to 250 words.
Manuscript Original Articles must not exceed 10 printed pages including figures, tables, and references. Manuscript must include Introduction, Materials and Methods, and Discussion sections, with a clear study design and at least three independent experiments reported. Manuscript must include a disclosure statement, a Data Availability Statement, and documentation of any large language model use in the Methods section or another suitable section if no Methods section is available.
References References must be cited in the text by name and year in parentheses. Reference list entries must include only works cited in the text that have been published or accepted for publication and must be alphabetized by the last name of the first author.
Figures & Tables Figures should be embedded within the manuscript text unless large file size prevents this, in which case they should be submitted separately. Tables and figures must be numbered in Arabic numerals, cited in consecutive numerical order in the text, and accompanied by captions.
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Short Reports

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be 150 to 250 words.
Manuscript Short Reports must not exceed 2 printed pages or approximately 1,000 words including tables. Manuscripts must include 4 to 6 keywords, a Declarations section before the reference list, and documentation of any large language model use in the Methods section or another suitable section if no Methods section is available.
References References must be cited in the text by name and year in parentheses. Reference list entries must include only works cited in the text that have been published or accepted for publication and must be alphabetized by the last name of the first author.
Figures & Tables Figures should be submitted within the body of the text unless large file size causes upload problems, in which case they should be submitted separately. Tables and figures must be numbered in Arabic numerals, cited in consecutive numerical order in the text, and provided with captions.
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Opinion Letters

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is optional for Opinion Letters. Abstract, if included, must be 150 to 250 words.
Manuscript Manuscript must not exceed 4 printed pages. Provide 4 to 6 keywords and include a Declarations section before the reference list, and any use of a large language model must be documented in a suitable part of the manuscript.
References Reference list is limited to 20 references. Citations must use name-and-year style. References must include only works cited in the text that are published or accepted for publication and must be alphabetized by the last name of the first author.
Figures & Tables No more than two figures and/or tables are allowed, and any additional figures or tables must be provided as electronic supplement. Figures should be submitted within the body of the text unless large file size causes upload problems, in which case they should be submitted separately. Authors may provide only minimum affiliations of institute and country without address.
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Recent Publications

Isatin–pyridine oxime hybrids as potential reactivators of A-242-inhibited acetylcholinesterase

Amanda M. V. Pinto, Dipanjan Bhattacharyya, Munique C. J. da Silva, Daniel A. S. Kitagawa, Marcelo C. dos Santos, Samir F. de A. Cavalcante, Salim T. Islam, Steven R. LaPlante, Pat Forgione, Joyce S. F. Diz, Tanos C. C. França

10.1007/s00204-026-04449-1
View Publication

AIComet: a reliable automated scoring program for DNA damage assessment in the comet assay

Adrien Germot, Nicolas Elie, Léonie Ibazizene, Sterenn Guillemot, Poppy Evenden, Peter Møller, Raphaël Delépée, Matthieu Meryet-Figuiere, Pierre Lebailly

10.1007/s00204-026-04432-w
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Lentiviral-mediated expression of cytochrome P450 2D6 in HepaRG cells: new means for in vitro xenobiotic biotransformation and cellular response to chimeric viral mRNA

Hugo Coppens-Exandier, Franz Mackanga, Thomas Darde, Corentin Bonhomme, Gaëlle Angenard, Patricia Leroyer, Catherine Ribault, Thomas Gicquel, Romain Pelletier, Flyuza Roshchina, Estelle Schaefer, Christophe Chesné, Agnès Jamin, Anne Corlu, Pascal Loyer

10.1007/s00204-026-04453-5
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Points of Departure for BPDE-induced cellular senescence and cell death are characterized by altered DNA damage signaling and regulated by unrepaired DNA double-strand breaks

Ariane Schmidt, Anna Schöneis, Jason Sallbach, Alexandra Pöschmann, Rebekka Lippold, Birgit Rasenberger, Thomas G. Hofmann, Maja T. Tomicic, Markus Christmann

10.1007/s00204-026-04426-8
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Unpacking amphotericin B toxicity: a critical review of amphotericin B aggregation and its link to toxicity and antifungal activity

Chandra Harshita Chavali, Evelyne Deplazes

10.1007/s00204-026-04420-0
View Publication

Frequently asked questions

How long does it take to publish?

Short communications are given priority in the editorial and production process. If a response letter is received within four weeks after invitation, both the original opinion piece and the response letter will be published in the same issue. Articles are published online after receipt of corrected proofs.

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Is a cover letter required?

A submission letter is used when suggesting reviewers if institutional email addresses are unavailable, and the corresponding author should mention any unpublished material included in the manuscript in a cover letter to the Editor.

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What are the publication costs?

Open access APC: £3990.00 GBP / $5990.00 USD / €4690.00 EUR. Subscription publishing has no APC. APC is determined from the date of acceptance and may be subject to VAT or local taxes.

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Research Topics

Carcinogens and Genotoxicity Assessment Poisoning and overdose treatments Effects and risks of endocrine disrupting chemicals Pesticide Exposure and Toxicity Pharmacogenetics and Drug Metabolism Heavy Metal Exposure and Toxicity Drug-Induced Hepatotoxicity and Protection Toxic Organic Pollutants Impact Drug Transport and Resistance Mechanisms Trace Elements in Health Animal testing and alternatives Air Quality and Health Impacts Genomics, phytochemicals, and oxidative stress Environmental Toxicology and Ecotoxicology Glutathione Transferases and Polymorphisms Metabolism and Genetic Disorders Insect and Pesticide Research Cholinesterase and Neurodegenerative Diseases Computational Drug Discovery Methods Neuroscience and Neuropharmacology Research Mercury impact and mitigation studies Mycotoxins in Agriculture and Food Contact Dermatitis and Allergies Forensic Toxicology and Drug Analysis Metabolomics and Mass Spectrometry Studies

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