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Cell Host & Microbe

Cell Host & Microbe was launched in March 2007 and provides a forum for the exchange of ideas between scientists studying microbes and those studying host immune, cell biological, and molecular responses upon colonization or infection. The journal publishes novel findings related to bacteria, fungi, parasites, and viruses from molecular and cellular biology to translational studies, with particular emphasis on interactions between microbes and their hosts. It publishes primary research manuscripts as well as expert analysis, commentary, and reviews on topics of current interest in the field.

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Subject Virology
Impact Factor 18.7
Quartile Q1
Open Access Type Hybrid
ISSN 1931-3128
eISSN 1934-6069
Invitation Only No
Cost Range No fee under the default subscription model; open access APC charges are referenced on the Cell Press open access page.

Submission Instructions

Cell Host & Microbe accepts the following article types. Click on an article type to view submission instructions.

Research

Cover Letter Cover Letter requirements are not specified.
Abstract A single-paragraph Summary is required. The Summary must be 150 words or fewer. The Summary must be unstructured as a single paragraph.
Manuscript The total word count must be under 7,000 words, including the title, author list, affiliations, main text, and main figure legends but excluding STAR Methods text, supplemental item legends, and references. The main document must include sections in this order: title, author list and affiliations, Lead Contact footnote, corresponding author email address(es), Summary, Introduction, Results, Discussion, Resource Availability, Acknowledgments, Author Contributions, Declaration of Interests, main figure titles and legends, main tables and legends, STAR Methods text, supplemental video and Excel table titles and legends, and References. The manuscript must include a Resource Availability section with the subsections lead contact, materials availability, and data and code availability, an Author Contributions section using author initials, Highlights of 3 to 4 bullet points, an eTOC blurb of no more than 50 words, a Declaration of Interests section, and if applicable a Declaration of generative AI and AI-assisted technologies in the writing process section.
References References must be cited in numbered superscript style in consecutive order. References must be numbered by first citation order, use "et al." only after 10 author names, and article references must include the author list, year, article title, journal abbreviation, volume, page range, and DOI.
Figures & Tables Articles may include no more than seven figures and/or tables. For accepted manuscripts, main figures must be uploaded individually as separate files and figure titles and legends and main-text tables must appear in the main manuscript at the end. Each figure file must contain all panels on a single page, figures containing micrographs must include scale bars, and tables must be editable Word tables rather than images.
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Resource

Cover Letter Cover letter should be included and explain prior knowledge, the conceptual advance, the significance and potential impact of the work, and whether the paper is part of a consortium. Cover letter should explain what was previously known, the conceptual advance provided by the work, the significance and potential impact of the work, and indicate if the paper is part of a consortium.
Abstract Summary must be a single paragraph of no more than 150 words. Summary must be unstructured as a single paragraph.
Manuscript Manuscript must have a total word count under 7,000 including the title, author list, affiliations, main text, and main figure legends but excluding STAR Methods text, supplemental item legends, and references. Manuscript must include, in order, title, author list and affiliations, Lead Contact footnote, corresponding author email address(es), Summary, Introduction, Results, Discussion, Resource Availability, Acknowledgments, Author Contributions, Declaration of Interests, main figure titles and legends, main tables and legends, STAR Methods text, supplemental video and Excel table titles and legends, and References. Manuscript must include a Resource Availability section with lead contact, materials availability, and data and code availability subsections, an Author Contributions section using author initials, a Declaration of Interests section, a separate declaration section for any generative AI use in writing, up to 10 keywords after the Summary, and separate Highlights and eTOC blurb files.
References References must use numbered superscript citations in consecutive order. References must be numbered sequentially by first citation and include only published or in-press items, with article references listing author list, year, title, journal abbreviation, volume, page range, and DOI.
Figures & Tables No more than seven figures and/or tables may be included. For accepted manuscripts, main figures must be uploaded individually as separate files and figure titles and legends and main tables must appear in the main manuscript document. Tables must be editable Word tables rather than images and figures and tables must include descriptive titles.
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Theory

Cover Letter Cover letter should be included. Cover letter should explain what was previously known, the conceptual advance provided by the work, the significance and potential impact of the work, and whether the paper is part of a consortium.
Abstract A summary or abstract is required. Summary must be a single paragraph of no more than 150 words. Summary must be unstructured as a single paragraph.
Manuscript Main document should contain no more than 7,000 words including the title page and excluding STAR Methods, supplemental video and Excel table legends, and references. Main document must include title, author list and affiliations, Lead Contact footnote, corresponding author email addresses, Summary, Introduction, Results, Discussion, Resource Availability, Acknowledgments, Author Contributions, Declaration of Interests, main figure titles and legends, main tables and legends, STAR Methods text, supplemental video and Excel table titles and legends, and References in that order. A separate Word document containing 3 to 4 Highlights, an eTOC blurb of no more than 50 words, a Declaration of Interests section in the manuscript, an Author Contributions section using initials, and if applicable a Declaration of Generative AI and AI-assisted technologies in the writing process must be provided.
References References must use numbered superscript citations in consecutive order. References must be numbered by first citation order, use "et al." only after 10 author names, include only one article per reference, and article references must include the author list, year, title, journal abbreviation, volume, page range, and DOI.
Figures & Tables Article should contain no more than seven main figures and/or tables. For accepted manuscripts, main figures must be uploaded individually as separate files while figure titles and legends and main-text tables must appear in the main manuscript. Tables must be editable Word tables rather than images and figures for two-column formats may have maximum widths of 8.5 cm for 1 column, 11.4 cm for 1.5 columns, and 17.4 cm for full width.
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Clinical Translational Reports

Cover Letter Cover Letter requirements are not specified.
Abstract Summary must be a single paragraph of no more than 150 words. Summary must be unstructured as a single paragraph.
Manuscript Main document should contain no more than 7,000 words including the title page and excluding STAR Methods, supplemental video and Excel table legends, and references. Main document must include title, author list and affiliations, Lead Contact footnote, corresponding author email address(es), Summary, Introduction, Results, Discussion, Resource Availability, Acknowledgments, Author Contributions, Declaration of Interests, main figure titles and legends, main tables and legends, STAR Methods text, supplemental video and Excel table titles and legends, and References in that order. Manuscript must include a Resource Availability section with lead contact, materials availability, and data and code availability subsections, an Author Contributions section using author initials, a Declaration of Interests section, separate Highlights and eTOC blurb files, and a Declaration of Generative AI and AI-assisted technologies in the writing process section if applicable.
References References must be cited in numbered superscript style. References must be numbered sequentially by first citation, use et al. only after 10 author names, and include only published or in-press works in the reference list.
Figures & Tables Article should contain no more than seven main figures and/or tables. Main figures must be uploaded individually as separate files and main tables must appear at the end of the manuscript in a separate section after the figure legends. Each figure must have all panels together on a single page with a descriptive title and legend, and tables must be editable Word tables with a descriptive title and no panel subdivisions.
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Review

Cover Letter Cover letter should be included. Cover letter should explain what was previously known, the conceptual advance provided by the work, the significance and potential impact of the work, and indicate if the paper is part of a consortium.
Abstract Abstract is required. Abstract must not exceed 150 words. Abstract should be unstructured as a single paragraph.
Manuscript Manuscript should be 5,000 to 8,000 words in length, including the abstract. Manuscript must include sections in this order: title, author list and affiliations, Lead Contact footnote, corresponding author email address(es), Summary, Introduction, Results, Discussion, Resource Availability, Acknowledgments, Author Contributions, Declaration of Interests, main figure titles and legends, main tables and legends, STAR Methods text, supplemental video and Excel table titles and legends, and References. Manuscript must include Highlights of 3 to 4 bullet points, an eTOC blurb of no more than 50 words, a Declaration of Interests section, and if applicable a declaration of generative AI and AI-assisted technologies in the writing process.
References References may include up to 100 entries. References must use numbered superscript citations in Vancouver-style format. References must be numbered sequentially by first citation, use "et al." only after 10 author names, and include full publication details with DOI where applicable.
Figures & Tables Manuscript may include three to five figures. For accepted manuscripts, figures must be uploaded individually as separate files and table content must appear in the manuscript rather than as images. Tables must be editable Word tables, and figure maximum widths are 8.5 cm for 1 column, 11.4 cm for 1.5 columns, and 17.4 cm for full-page width.
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Minireview

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required and must not exceed 100 words. The abstract must be no more than 100 words.
Manuscript The article may be 3,500 to 5,000 words in length including the abstract. A separate Word document containing 3 to 4 Highlights and an eTOC blurb of no more than 50 words is required, and any use of generative AI or AI-assisted technology in writing must be disclosed in a section after the Declaration of Interests.
References The article may include no more than 35 references. References must be cited as consecutively numbered superscripts, and “et al.” should be used only after 10 author names.
Figures & Tables The article may include 1 to 3 figures. For accepted manuscripts, figures must be uploaded individually as separate files and tables must appear at the end of the manuscript. Tables must be editable Word tables rather than images, and figure maximum widths are 8.5 cm for one column, 11.4 cm for 1.5 columns, and 17.4 cm for full-page width.
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Short Article

Cover Letter Cover Letter requirements are not specified.
Abstract A summary is required. The summary must be a single paragraph of no more than 150 words. The summary must be unstructured as a single paragraph.
Manuscript The manuscript must be under 4,000 words including the title, author names and affiliations, summary, and figure legends, but excluding STAR Methods text, supplemental item legends, and references. The manuscript must include the sections title, author list and affiliations, Lead Contact footnote, corresponding author email address(es), Summary, Introduction, Results, Discussion, Resource Availability, Acknowledgments, Author Contributions, Declaration of Interests, main figure titles and legends, main tables and legends, STAR Methods text, supplemental video and Excel table titles and legends, and References in that order. The manuscript must include a Resource Availability section with the subsections lead contact, materials availability, and data and code availability, an Author Contributions section using author initials, a Declaration of Interests section, Highlights and an eTOC blurb as separate submission items, and a declaration section after Declaration of Interests if generative AI or AI-assisted writing tools were used.
References References must be cited in numbered superscript style. References must be numbered sequentially by first citation, include only published or in-press works, and use et al. only after 10 author names.
Figures & Tables The article may include no more than 4 figures and/or tables, no more than 4 supplemental figures, and up to 8 supplemental items in total for tables and/or movies. For accepted manuscripts, main figures must be uploaded individually as separate files and figure titles and legends and main-text tables must appear in the main manuscript at the end. Each figure must include all panels on a single page with a descriptive title, and tables must be editable Word tables with a descriptive title and no panel subdivisions.
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Brief Report

Cover Letter Cover Letter requirements are not specified.
Abstract Summary must be a single paragraph of no more than 150 words. Summary must be unstructured as a single paragraph.
Manuscript Main text must not exceed 2,500 words, excluding STAR Methods, figure legends, and references. Manuscript must include a Resource Availability section with the subsections lead contact, materials availability, and data and code availability, and the experimental procedures section must be presented as part of the supplemental information. Manuscript must include an author contributions section using initials to concisely describe each author's contributions, and if generative AI or AI-assisted technology was used in the writing process, a declaration section must appear after the Declaration of Interests section.
References References must be cited in numbered superscript style. References must be numbered sequentially by first citation, use 'et al.' only after 10 author names, and include only published or in-press material in the reference list.
Figures & Tables Brief Reports may include no more than two main figures and/or tables, no more than two supplemental figures, and up to four supplemental items total including tables and/or movies. Main figures must be uploaded individually as separate files with figure titles and legends placed at the end of the main manuscript, while experimental procedures must appear in the supplemental information. Tables must be editable Word tables rather than images, and each figure file must contain all panels together on a single page.
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Recent Publications

Phages as ecosystem engineers of plant microbiomes

Xiaofang Wang, Ville-Petri Friman, Zhong Wei

10.1016/j.chom.2026.03.021
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What the nose knows of cystic fibrosis microbes and hypertonic saline

Drake C. Bouzek

10.1016/j.chom.2026.04.017
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The human skin virome: Ecological dynamics, aberrant profiles, and therapeutic opportunities

You Che, Heidi H. Kong

10.1016/j.chom.2026.04.008
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Diversity recruits resilience via metabolite signaling

Xiu-Tong Li, Jian Feng

10.1016/j.chom.2026.03.022
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Predicting phage anti-defenses that shoot the messenger

Marina Mahler, Li Yuping

10.1016/j.chom.2026.04.014
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Frequently asked questions

How long does it take to publish?

3 days from submission to first decision; 77 days from submission to acceptance.

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Is a cover letter required?

A cover letter is included among the materials to prepare for submission and a cover letter or point-by-point response is included for final submission.

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What are the publication costs?

No fee to publish under the default subscription model. Open access APC charges apply and are listed on the Cell Press open access page.

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Research Topics

Gut microbiota and health Mosquito-borne diseases and control HIV Research and Treatment Clostridium difficile and Clostridium perfringens research interferon and immune responses Bacteriophages and microbial interactions Viral gastroenteritis research and epidemiology Immune Cell Function and Interaction Vibrio bacteria research studies Plant-Microbe Interactions and Immunity Viral Infections and Vectors Cytomegalovirus and herpesvirus research SARS-CoV-2 and COVID-19 Research Immune Response and Inflammation Probiotics and Fermented Foods Malaria Research and Control Escherichia coli research studies CRISPR and Genetic Engineering Influenza Virus Research Studies Insect symbiosis and bacterial influences Toxoplasma gondii Research Studies Herpesvirus Infections and Treatments Diet and metabolism studies Plant Virus Research Studies Autophagy in Disease and Therapy