CM

Cell Metabolism

Cell Metabolism is a research journal focused on publishing novel, impactful papers spanning basic to clinical metabolic research, including original research on the molecular mechanisms underlying physiological homeostasis and disease.

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Subject Endocrinology & Metabolism
Impact Factor 30.9
Quartile Q1
Open Access Type Hybrid
ISSN 1550-4131
eISSN 1932-7420
Invitation Only No
Cost Range Article publishing charge: $10,400 for open access publication.

Submission Instructions

Cell Metabolism accepts the following article types. Click on an article type to view submission instructions.

Primary Research Manuscripts

Cover Letter All authors and the responsible authorities where the work was carried out must approve publication of the manuscript.
Abstract Abstract requirements are not specified.
Manuscript Most research articles should include an introduction, results, discussion, resource availability section, and STAR Methods. Most research articles should include keywords, acknowledgments, author contributions, a declaration of interests section, a declaration of generative AI and AI-assisted technologies section, and a supplemental information index if applicable.
References References requirements are not specified.
Figures & Tables Supplemental files must be uploaded separately and not as part of the main-text manuscript. Figure and scheme titles and legends and tables should be included in most research articles.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract is required. Abstract must not exceed 150 words.
Manuscript Manuscript must be 5,000 to 8,000 words in length. Manuscript must include a declaration of interests section and, if applicable, a section titled "Declaration of generative AI and AI-assisted technologies in the writing process" after the declaration of interests section.
References References requirements are not specified.
Figures & Tables Manuscript must include three to five figures. Supplemental files must be uploaded separately and not as part of the main-text manuscript.
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Research Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must have a total word count under 7,000, including main figure legends but excluding STAR Methods text, supplemental item legends, and the references section. Manuscript must include a resource availability section with the subsections lead contact, materials availability, and data and code availability, and it must include sufficient methods in the STAR Methods section. Manuscript must include concise author contributions using author initials, a materials availability statement even if no materials were generated, a three-part data and code availability statement with data, code, and additional information sections including any accession numbers and DOIs, a declaration of interests section, and a declaration of generative AI and AI-assisted technologies section.
References References requirements are not specified.
Figures & Tables Research Articles may include no more than 7 figures and/or tables. Supplemental files must be uploaded separately and not as part of the main-text manuscript.
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Resource

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript word count must be under 7,000 words including main figure legends but excluding STAR Methods text, supplemental item legends, and the references section. Manuscript must include a STAR Methods section with detailed description of methods and analytical/statistical methods. Manuscript must include a declaration of interests section and a declaration of generative AI and AI-assisted technologies in the writing process section.
References References requirements are not specified.
Figures & Tables Manuscript may include no more than 7 main figures and/or tables. Supplemental files must be uploaded separately and not as part of the main-text manuscript.
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Short Article

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Manuscript must have a total word count under 4,000 words, including figure legends but excluding STAR Methods text, supplemental item legends, and the references section. Short Articles may combine the Results and Discussion sections and must include sufficient methods in the STAR Methods section. Manuscript must include a declaration of interests section and, if applicable, a section titled "Declaration of generative AI and AI-assisted technologies in the writing process" placed after the declaration of interests section.
References References requirements are not specified.
Figures & Tables Short Articles must include no more than 4 figures and/or tables. Supplemental files must be uploaded separately and not as part of the main-text manuscript.
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Clinical And Translational Reports

Cover Letter All authors and the responsible authorities where the work was carried out must approve publication of the manuscript.
Abstract Abstract requirements are not specified.
Manuscript Total word count must be under 7,000 words, including main figure legends but excluding STAR Methods text, supplemental item legends, and the references section. Manuscript must include sufficient methods in the STAR Methods section. Manuscript must include a declaration of interests section and, if applicable, a section titled "Declaration of generative AI and AI-assisted technologies in the writing process" after it.
References References requirements are not specified.
Figures & Tables Manuscript may include no more than 7 figures and/or tables. Supplemental files must be uploaded separately and not as part of the main-text manuscript.
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Letter

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Letters must be no more than 1,000 words. Letters should be submitted with a concise title and must not use the title "Letter to the Editor" or "Response to X." The manuscript must include a declaration of interests section and, if applicable, a section titled "Declaration of generative AI and AI-assisted technologies in the writing process" after the declaration of interests section.
References Letters are strictly limited to 10 references.
Figures & Tables Figures are not permitted in the main text of Letters.
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Recent Publications

Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle

Clara Bien Peek, Daniel C. Levine, Jonathan Cedernaes, Akihiko Taguchi, Yumiko Kobayashi, Stacy J. Tsai, Nicolle A. Bonar, Maureen R. McNulty, Kathryn Moynihan Ramsey, Joseph Bass

10.1016/j.cmet.2026.07.017
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Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer

Yingsheng Zhang, Meng-Ju Wu, Wan-Chi Lu, Yi-Chuan Li, Chun Ju Chang, Jer-Yen Yang

10.1016/j.cmet.2026.07.016
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Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11

Bing Zhou, Yunchen Luo, Hanqi Bi, Ni Zhang, Mingyue Ma, Zhixia Dong, Nana Ji, Shuo Zhang, Xiaoye Wang, Yuejun Liu, Xiaozhen Guo, Wei Wei, Cen Xie, Ling Wu, Xinjian Wan, Ming-Hua Zheng, Bing Zhao, Yao Li, Cheng Hu, Yan Lu

10.1016/j.cmet.2026.07.013
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Enhanced non-enzymatic H2S generation extends lifespan and healthspan in male mice

María Ángeles Cáliz-Molina, Raúl López-Fernández-Sobrino, Inmaculada Pino-Pérez, Concepción Panadero-Morón, María del Carmen Vilches-Pérez, María Camacho-Cabrera, Almudena García-Ruiz, Leopoldo Pérez-Rosendo, Isabel Espadas, Alejandro Sola-García, Mario Soriano-Navarro, Franz Martin, Mónica Venegas-Calerón, Joaquín Jesús Salas, Enrique Martínez-Force, Luis C. Romero, Ángeles Aroca, Román González-Prieto, Máximo Bernabeu-Wittel, Vivian Capilla-González, Christopher Hine, Alejandro Martín-Montalvo

10.1016/j.cmet.2026.07.014
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Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism

Jie Jiang, Yuqing Gao, Jiang Wang, Yan Huang, Rong Yang, Yongxin Zhang, Yuandi Ma, Yingquan Wen, Gongkai Luo, Shurui Zhang, Yutang Cao, Minjun Yu, Qinxue Wang, Shulei Hu, Kanglong Wang, Xiaozhen Guo, Frank J. Gonzalez, Yameng Liu, Hong Liu, Qing Xie, Cen Xie

10.1016/j.cmet.2026.07.015
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Frequently asked questions

How long does it take to publish?

Median 7 days from submission to first editorial decision and median 28 days from acceptance to first online publication.

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Is a cover letter required?

A cover letter is included among the materials to prepare for submission. A cover letter or point-by-point response is also listed for final submission.

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What are the publication costs?

Hybrid journal with an article publishing charge of $10,400 for open access publication.

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Research Topics

Adipose Tissue and Metabolism Pancreatic function and diabetes Mitochondrial Function and Pathology Diet and metabolism studies Metabolism, Diabetes, and Cancer Regulation of Appetite and Obesity Cancer, Hypoxia, and Metabolism Adipokines, Inflammation, and Metabolic Diseases Genetics, Aging, and Longevity in Model Organisms Liver Disease Diagnosis and Treatment Epigenetics and DNA Methylation Circadian rhythm and melatonin Peroxisome Proliferator-Activated Receptors Lipid metabolism and biosynthesis Gut microbiota and health Immune cells in cancer Dietary Effects on Health Immune Cell Function and Interaction Biochemical Analysis and Sensing Techniques Diabetes and associated disorders Diet, Metabolism, and Disease RNA modifications and cancer Autophagy in Disease and Therapy Endoplasmic Reticulum Stress and Disease ATP Synthase and ATPases Research

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