Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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CC
Clinical Chemistry is a journal published by Oxford University Press for the Association for Diagnostics & Laboratory Medicine in the field of laboratory medicine and clinical chemistry. The journal features research articles, clinical case studies, special issues, podcasts, and other scholarly content, and lists a 2024 Impact Factor of 6.3 with a ranking of 1/33 in Medical Laboratory Technology.
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Subject
Medical Laboratory Technology
Impact Factor
6.3
Quartile
Q1
Open Access Type
Hybrid
ISSN
0009-9147
eISSN
1530-8561
Invitation Only
No
Cost Range
No submission fee. Open access publication is available for an open access charge after acceptance. Print color figures cost $820 per figure; online-only color is free.
Submission Instructions
Clinical Chemistry accepts the following article types. Click on an article type to view submission instructions.
Article
Cover Letter
Cover letter is required only for expedited submission of an Article previously peer reviewed by another prominent journal. For expedited submission previously peer reviewed by another prominent journal, the cover letter must verify that communications with the prior journal are not under a nondisclosure or confidentiality agreement and that all prior journal emails and reviewer comments have been provided intact and unedited, and it must disclose any use of artificial intelligence to help generate content, write code, or process data.
Abstract
A structured abstract is required. Abstract must be limited to 250 words. Abstract must be structured. Abstract must use the headings Background, Methods, Results, and Conclusions.
Manuscript
Main text excluding abstract and references must not exceed 3,500 words. Text should be formatted with the headings Introduction, Methods, Results, and Discussion. Submission must include keywords on the first page, a Brief Summary of no more than 100 words addressing the paper’s rationale, approach, findings, and implications and including a simple phonetic spelling of the first author’s full name, and alt text descriptions in the main manuscript file directly under each relevant figure legend.
References
No more than 40 references are permitted. In-text citations must use numbered references in the form (1) or (1, 2), and references must be listed and numbered in order of appearance with the first six authors followed by et al. when there are more than seven authors.
Figures & Tables
No more than 6 tables and/or figures in total are permitted. Tables must be embedded directly following the reference section, while all figures must be uploaded separately as image files and not embedded in the manuscript file. Each table must appear on an individual page and be labeled and numbered consecutively, and figure legends must be listed together on an individual page directly following the tables or the references if there are no tables.
Comprehensive Review
Cover Letter
Use of artificial intelligence to help generate content, write code, or process data must be disclosed in the cover letter. The cover letter must disclose any use of artificial intelligence to help generate content, write code, or process data.
Abstract
A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background, Content, and Summary.
Manuscript
Text must not exceed 5,000 words. Text should be formatted with the headings Introduction, Methods, Results, and Discussion. The first page must include keywords, word count, number of figures and tables, and a list of abbreviations, and alt text descriptions must be included in the main manuscript file directly under the relevant figure legend.
References
Submissions must have no more than 75 references. References must be numbered in order of appearance with in-text citations formatted as numbered parentheses, and for more than seven authors list the first six followed by et al.
Figures & Tables
Submissions must include no more than 6 tables and/or figures in total. Tables must be embedded directly after the references, and figures must be uploaded separately as image files. Figure legends must be provided together on a separate page and tables must be numbered consecutively with Arabic numerals.
Clinical Case Study
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must not be included.
Manuscript
Case description and case discussion are limited to 1,500 words total, excluding the questions and points to remember. Manuscript must include a case description followed by a case discussion. Manuscript must include 3–5 brief questions regarding the case, up to 5 points to remember at the end, and the case title, case description, and questions must not disclose the diagnosis.
References
References are limited to 10. References must be numbered in order of appearance in the text using numbered in-text citations formatted as (1) or (1, 2).
Figures & Tables
Tables and figures are limited to a combined total of 2. Tables must be embedded directly after the references, figure legends must follow the tables or references, figures must be uploaded separately, and supplemental data are not permitted.
Letter To The Editor
Cover Letter
Any use of artificial intelligence to help generate content, write code, or process data must be disclosed in the cover letter.
Abstract
Abstract must not be included.
Manuscript
Manuscript must not exceed 750 words. Text should be formatted with the headings Introduction, Methods, Results, and Discussion. The first page must include keywords, word count, number of figures and tables, and a list of abbreviations, and the manuscript should list no more than 8 authors.
References
References are limited to 5. References must be numbered in the order cited and formatted as numbered in-text citations such as (1) or (1, 2), listing all authors if there are 7 or fewer or the first 6 followed by et al. if there are more than 7.
Figures & Tables
Only 1 table or figure may be included. Tables must be embedded directly after the references, figures must be uploaded separately, and supplemental data are not permitted. The single table or figure must not be multipart.
Mini-Review
Cover Letter
Cover letter must disclose any use of artificial intelligence to help generate content, write code, or process data. Cover letter must include disclosure of any use of artificial intelligence to help generate content, write code, or process data.
Abstract
Abstract is required and must be structured for Mini-Review submissions. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Background, Content, and Summary.
Manuscript
Text must not exceed 3,500 words. Text should be formatted with the headings Introduction, Methods, Results, and Discussion. The first page must include keywords, word count, number of figures and tables, and a list of abbreviations in order cited.
References
Mini-Review submissions must have no more than 40 references. References must be numbered in the order cited, use numbered in-text citations in parentheses, and list the first six authors followed by et al. when there are more than seven authors.
Figures & Tables
Mini-Review submissions must include no more than 4 tables and/or figures in total. Tables must be embedded directly after the references, and figures must be uploaded separately as image files. Figure legends must be listed on a separate page after the tables or references, and alt text for each figure must be included in the main manuscript directly under the relevant figure legend.
Clinical Toxicology Series
Cover Letter
Use of artificial intelligence to help generate content, write code, or process data must be disclosed in the cover letter.
Abstract
An abstract must be supplied during online submission.
Manuscript
Manuscript must include a case description of no more than 75 words and a case discussion of no more than 250 words. Manuscript must include a case description, 3 questions, and a case discussion. The first page must include keywords, word count, number of figures and tables, and a list of abbreviations in order cited.
References
References must not exceed 5. References must be numbered in order of appearance and cited in text as numbered citations in parentheses.
Figures & Tables
Tables must be embedded directly after the references, figure legends must follow the tables or references, figures must be uploaded separately, and supplemental data are not permitted. Each table and figure must be clearly labeled and numbered consecutively, and alt text for each image must be included in the main manuscript directly under the relevant figure legend.
Special Report
Cover Letter
Use of artificial intelligence to help generate content, write code, or process data must be disclosed in the cover letter. Cover letter must disclose any use of artificial intelligence to generate content, write code, or process data.
Abstract
Special Report submissions must include an abstract. Abstract must not exceed 250 words. Abstract may be structured or unstructured.
Manuscript
Main text must not exceed 5,000 words. Text should be formatted with the headings Introduction, Methods, Results, and Discussion. Title page must include keywords, word count, number of figures and tables, a list of abbreviations, and any previous presentation of the manuscript.
References
References must not exceed 40. References must be numbered in the order cited, cited in text as numbered parentheses, and list the first six authors followed by et al. when there are more than seven authors.
Figures & Tables
Special Report submissions may include no more than 4 tables and/or figures in total. Tables must be embedded directly after the references, figure legends must follow the tables or references, and figures must be uploaded separately. Each table and figure must be clearly labeled and numbered consecutively, and figure legends should be limited to 60 words.
Editorial
Cover Letter
Use of artificial intelligence to help generate content, write code, or process data must be disclosed in the cover letter. The cover letter must disclose any use of artificial intelligence to help generate content, write code, or process data.
Abstract
Abstract is not permitted.
Manuscript
Manuscript must not exceed 1,500 words. Editorial-specific structural format is not stated. Keywords must be included on the first page.
References
References are limited to 15. References must be numbered in the order cited and formatted to match numbered in-text citations.
Figures & Tables
Tables and figures are not permitted.
Recent Publications
Novel Rapid Phenotypic Susceptibility Testing Techniques That Enhance Antimicrobial Stewardship and Clinical Decision-Making
Janiece S Glover, Romney Humphries
10.1093/clinchem/hvag033
View Publication
Point of Concern for Troponin Testing with High-Sensitivity Assays in the Near Patient Setting
Peter A Kavsak
10.1093/clinchem/hvag034
View Publication
Whose Role Is It, Anyway? Ensuring Correct Genomic Variant Nomenclature in Published Literature
Sadeem Qdaisat, Birgit Funke, Heather Mason-Suares
10.1093/clinchem/hvag031
View Publication
Performance, Safety, and Patient Experience of an Autonomous Robotic Phlebotomy Device: A Multicenter Trial
Luuk F P Giesen, Jeroen A Roest, Frederique M A Koopman, Martine M L Deckers, Helena Chon, Christian M Hackeng, Jurgen A Riedl, Michiel de Bruin, Brooke M Katzman, Warry van Gelder, Janne Cadamuro, Mads Nybo, Michael A Fouraux, Thijs C van Holten, Robert de Jonge
10.1093/clinchem/hvag029
View Publication
Comparing the Efficiency of Bisulfite and Enzymatic DNA Methylation Conversion Methods for Detection of Colorectal Cancer Biomarkers
Stellene Vitaro, Geraldine Laven-Law, Ganessan Kichenadasse, Kathryn Cornthwaite, Erin L Symonds, Jean M Winter
10.1093/clinchem/hvag018
View Publication
Frequently asked questions
How long does it take to publish?
For 2022, original research articles had a median time from submission to first editor decision of 1.5 days, median time from submission to final decision of acceptance of 93.4 days, median time from submission to final decision of rejection of 12.0 days, and median time from submission to online publication of 138.4 days.
Reformat to Clinical Chemistry using Livewrite PremiumIs a cover letter required?
A cover letter is required for submissions involving preprints, must disclose AI use, and must include prior journal decision materials and verification statements for certain expedited submissions. For What Is Your Guess?, the cover letter must state interest in contributing to that category.
Reformat to Clinical Chemistry using Livewrite PremiumWhat are the publication costs?
Subscription journal with open access publishing options.
Reformat to Clinical Chemistry using Livewrite PremiumResearch Topics
Metabolism and Genetic Disorders
Clinical Laboratory Practices and Quality Control
Metabolomics and Mass Spectrometry Studies
Renal function and acid-base balance
Neonatal Health and Biochemistry
Analytical Chemistry and Chromatography
Monoclonal and Polyclonal Antibodies Research
Lipoproteins and Cardiovascular Health
Molecular Biology Techniques and Applications
Diabetes, Cardiovascular Risks, and Lipoproteins
Folate and B Vitamins Research
Analytical Methods in Pharmaceuticals
Hemoglobinopathies and Related Disorders
Acute Myocardial Infarction Research
Mass Spectrometry Techniques and Applications
Thyroid Disorders and Treatments
Antibiotics Pharmacokinetics and Efficacy
Advanced Biosensing Techniques and Applications
Advanced Proteomics Techniques and Applications
Hormonal and reproductive studies
Cancer Genomics and Diagnostics
Health Sciences Research and Education
Iron Metabolism and Disorders
Radiopharmaceutical Chemistry and Applications
Blood groups and transfusion