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CNS Spectrums

CNS Spectrums covers all aspects of the clinical neurosciences, neurotherapeutics, and neuropsychopharmacology, particularly those pertinent to the clinician and clinical investigator. The journal features focused, in-depth reviews, perspectives, and original research articles, with emphasis on new therapeutics in psychiatry, mental health, and neurology, including first in man studies, proof of concept studies, and translational basic neuroscience studies. Subject coverage spans the full spectrum of neuropsychiatry, especially areas crossing traditional boundaries between neurology and psychiatry.

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Subject Clinical Neurology, Psychiatry
Impact Factor 4.1
Quartile Q1
Open Access Type Open
ISSN 1092-8529
eISSN 2165-6509
Invitation Only No
Cost Range Eligible authors at participating institutions may publish Gold Open Access at no cost to the author; terms and conditions vary.

Submission Instructions

CNS Spectrums accepts the following article types. Click on an article type to view submission instructions.

Original Research

Cover Letter A cover letter must be included with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract A structured abstract is required for Original Research submissions. The abstract must be no more than 250 words. The abstract must be structured. The abstract must use the headings Objective, Methods, Results, and Conclusion.
Manuscript The manuscript must be 6,000 words. The manuscript must be organized into Title page, Structured Abstract, Keywords, Introduction, Methods, Results, Discussion, Conclusion, Acknowledgements, Funding, Competing interests, References, and Tables and/or Figures. The manuscript must include keywords, a Competing interests declaration, and declarations describing any use of AI tools.
References The submission may include up to 100 references. References must use American Medical Association (AMA) style. References must be cited as superscript numbers in order of appearance, not alphabetized, list all authors when there are six or fewer and the first three followed by et al. when there are seven or more, use Index Medicus journal abbreviations, and not duplicate entries.
Figures & Tables The submission must include at least 2 tables and/or figures. Tables must appear in editable format at the end of the article, and figures must be submitted as separate files rather than interspersed in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and provided with captions, with figure captions supplied at the end of the manuscript text.
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Reviews

Cover Letter A cover letter must be included with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract An abstract is required. Abstract must not exceed 250 words. Abstract structure is not specified.
Manuscript Reviews have no word limit, but an ideal length of 3,000 words is recommended. Manuscript should be arranged as Title page, Abstract, Introduction, Body, Conclusion, Acknowledgements, Funding, Competing interests, and References. Manuscript may include 3 to 5 Clinical Implication points where appropriate, must include a Competing interests declaration, and must declare and describe any use of AI tools.
References Reviews have no reference limit, but ideally include up to 30 references. References must use AMA style. References must be cited as superscript numbers in order of appearance, not alphabetized, list all authors when there are six or fewer, list the first three authors followed by "et al." when there are seven or more, use Index Medicus journal abbreviations, and avoid duplicate entries.
Figures & Tables Reviews must include 2 to 6 tables and/or figures. Tables must appear in editable format at the end of the article and figures must be submitted as separate files rather than embedded in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and accompanied by captions, and alt-text must be provided for all figures.
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Regular Scholarly Reviews

Cover Letter A cover letter must be included with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract A structured abstract is required. The abstract must be structured.
Manuscript Manuscript must be up to 6000 words. The manuscript must include a Competing interests declaration and any use of AI tools to generate text, images, or analyse or extract insights from data or other materials must be declared and described.
References References must use American Medical Association (AMA) style. References must be superscripted in the text, numbered in order of appearance rather than alphabetically, list all authors when there are six or fewer and the first three followed by et al. when there are seven or more, use Index Medicus journal abbreviations, and not contain duplicates.
Figures & Tables Tables must appear in an editable format at the end of the article and figures must be submitted as separate files rather than interspersed in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and accompanied by captions, with figure captions supplied at the end of the manuscript text and alt-text provided for all figures.
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Systematic Reviews

Cover Letter A cover letter is required with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract A structured abstract is required. The abstract must be structured.
Manuscript The manuscript must include a Competing interests declaration and must declare and describe any use of AI tools, including AI-generated text, data analysis, or visual content.
References References must use American Medical Association (AMA) style. References must be superscripted in the text, numbered in order of appearance rather than alphabetized, list all authors when there are six or fewer and the first three followed by et al. when there are seven or more, use Index Medicus journal abbreviations, and not duplicate entries.
Figures & Tables Tables must appear in editable format at the end of the article and figures must be submitted as separate files rather than interspersed in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and accompanied by appropriate captions, with figure captions supplied at the end of the manuscript text.
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Meta-Analyses

Cover Letter A cover letter must be included with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract A structured abstract is required. The abstract must be structured.
Manuscript The manuscript must include NbN-2 compliant keywords for all substances studied, a Competing interests declaration, funding details for all authors including grant numbers, and a declaration describing any use of AI tools.
References References must use American Medical Association (AMA) style. References must be cited as superscript numbers in order of appearance, not alphabetized, list all authors when there are six or fewer or the first three followed by "et al." when there are seven or more, use Index Medicus journal abbreviations, and not duplicate entries.
Figures & Tables Tables must appear in editable format at the end of the article and figures must be submitted as separate files rather than interspersed in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and accompanied by appropriate captions, with figure captions supplied at the end of the manuscript text and alt-text provided for all figures.
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Short Reviews

Cover Letter A cover letter must be included with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract An abstract is required for Short Reviews. The abstract must be no more than 250 words. The abstract must be unstructured.
Manuscript Short Reviews have no word limit, but the ideal length is 3,000 words. The manuscript must be compiled in the following order: Title Page; Unstructured Abstract; Key Words; Introduction; Body; Conclusion; Acknowledgements; Financial Support; Competing Interests; References; Appendices as appropriate; Table(s) with caption(s) on individual pages; Figure caption(s) as a list. The manuscript must include key words, a Competing Interests declaration, and a declaration describing any use of AI tools.
References References must use American Medical Association (AMA) style. References must be cited as superscript numbers in order of appearance rather than alphabetically, list all authors when there are six or fewer and the first three followed by "et al." when there are seven or more, use Index Medicus journal abbreviations, and not duplicate entries.
Figures & Tables Tables must appear at the end of the article and not be interspersed in the text, while figures must be submitted as separate files and not interspersed in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and captioned appropriately, with figure captions supplied at the end of the manuscript text.
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Case-Based Review Article

Cover Letter A cover letter must be included with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract An abstract is required. The abstract must be unstructured and no more than 250 words. The abstract must be unstructured.
Manuscript The manuscript must be 2,500 words. The submission must be formatted as a literature review and include at least 3 case examples. The manuscript must include a Competing interests declaration, NbN-2 compliant keywords, and a declaration describing any AI tool use.
References References must use American Medical Association (AMA) style. References must be superscripted in the text, numbered in order of appearance rather than alphabetized, list all authors when there are six or fewer and the first three followed by "et al." when there are seven or more, use Index Medicus journal abbreviations, and not duplicate entries.
Figures & Tables The submission must include a minimum of 2 and a maximum of 6 tables and/or figures. Tables must appear in editable format at the end of the article and figures must be submitted as separate files rather than interspersed in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and accompanied by appropriate captions, with figure captions supplied at the end of the manuscript text.
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Guidelines

Cover Letter A cover letter must be included with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract An abstract is required. Abstract must be unstructured and no more than 250 words. Abstract must be unstructured.
Manuscript Manuscript must be 6,000 words. Manuscript must include an introduction. A Competing interests declaration must be included in the manuscript, and any use of AI tools must be declared and described in the manuscript.
References References must use American Medical Association (AMA) style. References must be cited as superscript numbers in order of appearance, not alphabetized, list all authors when there are six or fewer and the first three followed by et al. when there are seven or more, use Index Medicus journal abbreviations, and not duplicate entries.
Figures & Tables Submission must include 15-25 tables and/or figures. Tables must appear in editable format at the end of the article, and figures must be submitted as separate files rather than interspersed in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and provided with appropriate captions, with figure captions supplied at the end of the manuscript text.
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Letter To The Editor

Cover Letter A cover letter must be included with the submission. The cover letter must state when the manuscript draws on a thesis.
Abstract An abstract must not be included.
Manuscript The manuscript must not exceed 1,000 words. The submission must be formatted as a letter to the editor and must not be used to communicate new research. The manuscript must include a Competing interests declaration, and any use of AI tools to generate text, images, or analyse or extract insights from data or other materials must be declared and described.
References The submission may include a maximum of 5 references. References must use American Medical Association (AMA) style. References must be cited as superscript numerals, numbered in order of appearance rather than alphabetically, list all authors when there are six or fewer or the first three followed by "et al." when there are seven or more, use Index Medicus journal abbreviations, and not duplicate entries.
Figures & Tables Tables should be placed at the end of the article in editable format, and figures should be submitted as separate files rather than interspersed in the text. Tables, figures, and images must be cited in the text, numbered consecutively in Arabic numerals, and accompanied by appropriate captions, with figure captions supplied at the end of the manuscript text.
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Recent Publications

Valbenazine Improves Quality of Life, Functionality, and Movement Severity in Patients With Tardive Dyskinesia: Findings From the KINECT-PRO™ Study

Christoph U. Correll, M. Mercedes Perez-Rodriguez, Joseph P. McEvoy, David V. Sheehan, Gustavo Alva, Susan Mathias, Morgan Bron, Robert H. Farber, Hui Zhang, Eduardo Dunayevich, Ashok Parameswaran

10.1017/s1092852926101138
View Publication

Association Between Dextromethorphan/Bupropion with Diabetes Mellitus and Hyperglycemia: Reports to the Food and Drug Administration Adverse Event Reporting System (FAERS)

Yang Jing Zheng, Sabrina Wong, Gia Han Le, Angela T.H. Kwan, Christine E. Dri, Roger Ho, Taeho Greg Rhee, Hernan F. Guillen-Burgos, Roger S. McIntyre

10.1017/s1092852926101163
View Publication

Spatial Working Memory Across Psychiatric Disorders in Young Adults

Kenneth Wang, Jon E. Grant

10.1017/s1092852926101151
View Publication

The Relationship of Gambling Disorder to Obsessive-Compulsive Disorder

Jon E. Grant, Ibrahim H. Aslan, Megha Neelapu, Sophie Boutouis, Laurie Avila, Samuel R. Chamberlain

10.1017/s109285292610114x
View Publication

Pharmacologic Modulation of Orexin Signaling: Impact on Glucose-Insulin Homeostasis and Potential Mechanism of Antidepressant Action

Roger S. McIntyre, Sabrina Wong

10.1017/s1092852926101126
View Publication

Frequently asked questions

How long does it take to publish?

Median calendar days are tracked for submission to first decision, submission to first decision for peer-reviewed articles, submission to acceptance, and receipt in production to publication.

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Is a cover letter required?

A cover letter should be included with the submission.

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What are the publication costs?

Eligible authors at participating institutions may publish Gold Open Access at no cost to the author; terms and conditions vary.

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Research Topics

Diverse Scientific and Economic Studies Schizophrenia research and treatment Neurology and Historical Studies Treatment of Major Depression Obsessive-Compulsive Spectrum Disorders Bipolar Disorder and Treatment Functional Brain Connectivity Studies Cerebrospinal fluid and hydrocephalus Attention Deficit Hyperactivity Disorder Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes Legal case studies and regulations Neurotransmitter Receptor Influence on Behavior Mental Health and Psychiatry Autism Spectrum Disorder Research Tryptophan and brain disorders Child and Adolescent Psychosocial and Emotional Development Electroconvulsive Therapy Studies Psychosomatic Disorders and Their Treatments Mental Health Research Topics Epilepsy research and treatment Personality Disorders and Psychopathology Neurological disorders and treatments Mental Health Treatment and Access Eating Disorders and Behaviors Legal Cases and Commentary

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