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Eclinicalmedicine

eClinicalMedicine is an open access journal in The Lancet Discovery Science suite. It publishes basic, translational, clinical, and health systems research and is identified by ISSN 2589-5370.

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Impact Factor 10
Quartile Q1
Open Access Type Open
eISSN 2589-5370
Invitation Only No
Cost Range Article processing charge is payable upon acceptance for all full-length peer-reviewed article types; APC information is provided at https://www.thelancet.com/open-access.

Submission Instructions

Eclinicalmedicine accepts the following article types. Click on an article type to view submission instructions.

Articles

Cover Letter A cover letter is required for first submissions. Cover letter must explain why the paper should be published in eClinicalMedicine rather than elsewhere.
Abstract Articles must include a semistructured abstract. Abstract should be around 250 words. Abstract must be semistructured in five paragraphs. Abstract paragraphs must be Background, Methods, Findings, Interpretation, and Funding.
Manuscript Articles should be around 3500–5000 words. Primary research Articles must include a Research in context panel. Manuscript must include individual author contributions at the end of the text, a Declaration of interests section, a Role of the funding source section at the end of the Methods, an AI-use disclosure in the acknowledgments if applicable, and a data sharing statement at the end of the manuscript.
References Articles should have 30 references. References must use Vancouver numbering style. References must be cited sequentially in the text as superscript numbers after punctuation marks.
Figures & Tables First submissions should include the manuscript including tables and panels, and figures should also be included in the submission. When reporting Kaplan-Meier survival data, numbers at risk must be included at each timepoint.
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Review

Cover Letter A cover letter is required for first submissions. The cover letter must explain why the paper should be published in eClinicalMedicine rather than elsewhere.
Abstract A 150-word unstructured summary is required. The abstract must not exceed 150 words. The abstract must be unstructured.
Manuscript The manuscript should be around 3500–4000 words. The manuscript should include a brief section entitled “Search strategy and selection criteria.” The manuscript must include a “Search strategy and selection criteria” section describing the sources searched, including databases, MeSH and free-text terms and filters, reference lists from journals or books, and the criteria for including or excluding studies, and any use of generative AI in developing the Review should be described in the methods section with the tool, version, and prompts where applicable.
References The manuscript should have no more than 75 references. References must use Vancouver style. References must be cited sequentially in the text using superscript numbers after punctuation marks, and references in tables, figures, and panels must follow numerical order based on first citation in the text.
Figures & Tables The manuscript may include up to 5 items in total across figures, tables, and panels. The manuscript should be submitted including tables and panels, and figures should also be included with the first submission.
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Correspondence

Cover Letter A cover letter must be included with the first submission. The cover letter must explain why the paper should be published in eClinicalMedicine rather than elsewhere.
Abstract Abstract requirements are not specified.
Manuscript Correspondence responding to previous content must be no longer than 250 words, while correspondence of general interest unlinked to items published in the journal may be up to 400 words. Correspondence should be written in response to previous content published in eClinicalMedicine. An AI disclosure statement at the end of the article is required if generative AI or AI-assisted technologies were used for writing assistance.
References Correspondence responding to previous content should have no more than 5 references. References must use Vancouver numbering style with sequential superscript citations in the text. References must be cited sequentially in the text, and references in tables, figures, and panels must follow numerical order based on first citation in the text.
Figures & Tables Correspondence may include only one table or figure. The manuscript must include tables and panels in the first submission, and figures must also be included in the first submission.
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Recent Publications

“Magical relief”: the effectiveness of three stages of a video-based magic intervention on distress and pain in children aged 9–11 years during HPV mass vaccinations—a cluster-randomized trial

Anne W.E. Versluis, Edmond H.H.M. Rings, Arno A.W. Roest, Victor Middelkoop, Nienke Vreeken, Andrea W.M. Evers, Henriët van Middendorp

10.1016/j.eclinm.2026.103876
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Real-world comparison of brain [18F]FDG-PET imaging with CSF Alzheimer's disease biomarkers in a tertiary memory clinic setting

Neus Rabaneda-Lombarte, João Pedro Ferrari-Souza, Johanna Celedon, Eduardo R. Zimmer, Bradford C. Dickerson, Steven E. Arnold, Pia Kivisäkk, Alberto Serrano-Pozo

10.1016/j.eclinm.2026.103910
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Oropouche virus: transmission, epidemiology, genetic diversity, and public health implications

Lorenzo Subissi, James R. Otieno, Christopher Ruis, Ingrid Rabe, Anurag Agrawal, Laith Jamal Abu-Raddad, Esam I. Azhar, Martin Beer, Haroldo Bezerra, Leon Caly, Meera Chand, Ariamys Companioni, Tulio de Oliveira, Isabelle Dietrich, Christian Drosten, Pablo Duran, Nuno R. Faria, Adeola Fowotade, Lionel Gresh, Baoying Huang, Jason Kindrachuk, Marion P.G. Koopmans, Bette Korber, Yee-Sin Leo, Placide Mbala-Kingebeni, Martina McMenamin, Nada M. Melhem, Vincent J. Munster, Bruno T.D. Nunes, Bas B. Oude Munnink, Felipe G. Naveca, Malik Peiris, Gustavo Palacios, Paola Resende, Angel Rodriguez, Senjuti Saha, Tadaki Suzuki, Andrea Vicari, Anne von Gottberg, Pragya Yadav, Jairo Mendez-Rico, Maria D. Van Kerkhove, Diana P. Rojas

10.1016/j.eclinm.2026.103871
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Comments regarding “Effects of therapeutic interventions on long COVID: a meta-analysis of randomized controlled trials”

David Tuller

10.1016/j.eclinm.2026.103882
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Prediction of trajectories and outcomes in early-stage metabolic dysfunction-associated steatotic liver disease: a narrative review

Brittany Bromfield, Jeremy Chimene-Weiss, Gregory Gheewalla, Theodore Feldman, Emilie K. Mitten, Piero Portincasa, Gyorgy Baffy

10.1016/j.eclinm.2026.103921
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Frequently asked questions

How long does it take to publish?

Papers are aimed to be published online in 2–3 weeks from acceptance. Receipt of submission is acknowledged by email, in-house decisions are communicated quickly, and manuscripts that pass initial assessment are peer reviewed by at least two reviewers and a statistician.

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Is a cover letter required?

A covering letter should be uploaded at the Enter Comments stage of online submission and used to explain why the paper should be published in eClinicalMedicine rather than elsewhere. Detailed responses to reviewers’ comments in a covering letter are also necessary for revised submissions.

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What are the publication costs?

Manuscript submission is free. An article processing charge is payable after acceptance for all full-length peer-reviewed article types.

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Research Topics

COVID-19 Clinical Research Studies SARS-CoV-2 and COVID-19 Research Long-Term Effects of COVID-19 Global Maternal and Child Health HIV/AIDS Research and Interventions COVID-19 and healthcare impacts Vaccine Coverage and Hesitancy COVID-19 and Mental Health Health Systems, Economic Evaluations, Quality of Life COVID-19 epidemiological studies Liver Disease Diagnosis and Treatment Radiomics and Machine Learning in Medical Imaging Global Cancer Incidence and Screening Health disparities and outcomes Diabetes Treatment and Management Neonatal Respiratory Health Research Child Nutrition and Water Access Chronic Obstructive Pulmonary Disease (COPD) Research Suicide and Self-Harm Studies Intensive Care Unit Cognitive Disorders Obesity, Physical Activity, Diet Pneumonia and Respiratory Infections Tuberculosis Research and Epidemiology HIV Research and Treatment Respiratory Support and Mechanisms