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Expert Opinion on Biological Therapy

Expert Opinion on Biological Therapy is a MEDLINE-indexed international hybrid journal focused on biological therapy, including gene therapy, gene transfer technologies, therapeutic peptides and proteins, vaccines and antibodies, cell-based therapies, stem cell therapies, and tissue-based therapies. It publishes rigorously peer-reviewed review articles and original papers, uses double-anonymous peer review after editorial suitability assessment, and does not publish case reports or case series.

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Impact Factor 4
Quartile Q2
Open Access Type Closed
ISSN 1471-2598
eISSN 1744-7682
Invitation Only Yes
Cost Range Institutional online-only subscription: USD 9,716.00; institutional print and online subscription: USD 14,201.00.

Submission Instructions

Expert Opinion on Biological Therapy is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract headings must appear in this order: Introduction, Areas covered, and Expert Opinion/Commentary.
Manuscript The body of the article must not exceed 7000 words. Manuscript should include Introduction, body sections with numbered subsections, Conclusion placed before Expert Opinion, and an Expert Opinion section ending with a speculative five-year viewpoint. Manuscript must include an Article Highlights section, 4–10 keywords in alphabetical order, and an annotated bibliography using one- and two-star highlights with brief annotations.
References Review Articles should include around 100 references. References must follow NLM style. References must be numbered consecutively in order of first mention and presented in a numerical reference list with bracketed square-number citations.
Figures & Tables Review Articles may include up to 5 figures and up to 5 tables. Previously published figures require written permission and the permission documentation must be uploaded with the manuscript.
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Original Research

Cover Letter Original Research submissions must include a covering letter. Cover letter must include the corresponding author’s full contact details, statements of originality and exclusive submission, confirmation that all authors approved the manuscript and met ICMJE conditions, the body granting ethical approval, any financial or other declarable relationships and support, and details of any prior abstract, poster, or oral presentation.
Abstract Original Research articles must include a structured abstract on the second page. Abstract must be no more than 200 words. Abstract must be structured. Abstract headings are stated inconsistently as either Introduction, Areas covered, and Expert Opinion/Commentary or Background, Research design and methods, Results, and Conclusions.
Manuscript Manuscript body must include introduction, patients and methods, results, discussion, and conclusions sections. Manuscript must include 4–6 keywords in alphabetical order, an acknowledgements section, an author contributions section, a disclosure of financial and competing interests, and a statement disclosing whether and how generative AI was used.
References References must use NLM style. References must be numbered consecutively in order of first mention and cited in the text as square-bracketed numbers, with the reference list presented in numerical order.
Figures & Tables A maximum of five tables is permitted. Tables must be supplied as editable files.
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Drug Evaluation

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order.
Manuscript Manuscript must not exceed 3,000 words excluding tables, figures, and references. Manuscript must include an introduction, a body covering overview of the market, introduction to the compound, clinical efficacy, safety and tolerability, regulatory affairs, and conclusion, plus an Expert Opinion section focused on approved uses of the drug. Manuscript must include an Article Highlights section, 5–8 keywords in alphabetical order, a Drug summary box, and a statement disclosing whether and how generative AI was used in the research and manuscript preparation process.
References References should not exceed 100. References must follow NLM style. References must be numbered consecutively in order of first mention using square-bracketed citations and important references must be marked with one or two asterisks plus brief annotations.
Figures & Tables Drug Evaluations may include up to five figures and up to five tables.
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Clinical Trial Evaluation

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order.
Manuscript Manuscript must include the clinical trial number and registration date, usually in the abstract and methods sections, and be structured to incorporate the author's expert opinion on the topic's impact on research and clinical practice and scope for future development. Manuscript must include 5–8 keywords and a statement disclosing whether and how generative AI was used in the research and manuscript preparation process.
References References must follow NLM style. References must be numbered consecutively in order of first mention and cited in the text, tables, and captions using bracketed square-bracket numbers, with the reference list presented in numerical order.
Figures & Tables A maximum of five tables is allowed. Tables must present new information rather than duplicate the text, be interpretable without reference to the text, and be supplied as editable files.
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Letter To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required for Letter To The Editor submissions. Abstract must not exceed 200 words. Abstract must be structured. Abstract must include the headings Introduction, Areas covered, and Expert Opinion/Commentary in that order, and it must not contain references.
Manuscript Manuscript must not exceed 1500 words. Letter To The Editor submissions must discuss articles previously published in the journal and provide a useful, objective critique pertinent to recently published Dove Medical Press articles. Manuscript must include 5–8 keywords and a statement disclosing whether and how generative AI was used in the research and manuscript preparation process.
References References must not exceed 15 entries and must include the article under discussion. References must follow NLM style. References must be numbered consecutively in order of first citation and presented in numerical order using square-bracketed numbers.
Figures & Tables Figures are not permitted and tables are not permitted.
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Recent Publications

Dual REmission in moderate-to-severe AsthMa and nasal polyps: a multicentric observational phase IV real-life study (DREAM-NP)

Francesco Menzella, Eugenio De Corso, Marco Caminati, Walter Cestaro, Laura Ventura, Paolo Cameli, Sara Munari, Umberto Semenzato, Rory Chan, Alvise Berti, Angelo Ghidini, Paolo Russo, Isabella Ruzzon, Alessio De Massimi, Maria Rita Marchi, Carlo Lombardi, Michela Bortoli, Claudia Rinaldo, Riccardo Pozzan, Fabio Giuseppe Vassallo, Francesco Gialdini, Tatiana Scandiuzzi Piovesan, Marcello Cottini, Gianenrico Senna, Lorenzo Corsi, Antonio Romano, Andrea Tozzi, Giancarlo Ottaviano

10.1080/14712598.2026.2710254
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Breaking immune exclusion in cold tumors via TGF-β pathway inhibition

Minjun Zhang, Yuchen Sun, Luyan Chen, Dixuan Xue, Di Zhang, Ming Yi, Zhijun Dai

10.1080/14712598.2026.2709483
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Sequencing and switching among IL-17 and IL-23 biologics in plaque psoriasis: real-world lessons and precision strategies for the future

Clarissa Fava, Edoardo Zompanti, Eleonora De Luca, Clara De Simone, Ketty Peris, Giacomo Caldarola

10.1080/14712598.2026.2706714
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Anakinra treatment practices in colchicine-resistant familial Mediterranean fever: a survey of pediatric rheumatologists conducted through the PReS AID-WP and the Turkish pediatric rheumatology associations

Sıla Atamyıldız Uçar, Eray Tunce, Betül Sözeri

10.1080/14712598.2026.2703145
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Targeting autoimmune pulmonary alveolar proteinosis with GM-CSF: insights from clinical trials and emerging therapies

Margaret Higgins, Niamh Boyle, Cormac McCarthy

10.1080/14712598.2026.2706713
View Publication

Frequently asked questions

How long does it take to publish?

Accepted Author Version is published online in 3 days if the copyright form has been received. Accelerated Publication Plus offers a final decision in as little as 3 weeks, with online publication usually 1-2 weeks after acceptance and first proofs within 5 working days. Accelerated Publication offers a final decision in as little as 9 weeks, with online publication usually 2-3 weeks after acceptance and first proofs within 5 working days.

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Is a cover letter required?

A covering letter is required. It must include corresponding author contact details, statements of originality and exclusive submission, confirmation that all authors approved the manuscript and ICMJE conditions were met, ethical approval information, and disclosure of financial or other relationships. Manuscripts without a covering letter or a Disclosure Form are not considered complete submissions.

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What are the publication costs?

Institutional online-only subscription: USD 9,716.00; institutional print and online subscription: USD 14,201.00.

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Research Topics

Immunotherapy and Immune Responses Virus-based gene therapy research Monoclonal and Polyclonal Antibodies Research CAR-T cell therapy research Cancer Immunotherapy and Biomarkers RNA Interference and Gene Delivery Mesenchymal stem cell research Biosimilars and Bioanalytical Methods Psoriasis: Treatment and Pathogenesis Rheumatoid Arthritis Research and Therapies Pluripotent Stem Cells Research Immune Cell Function and Interaction HER2/EGFR in Cancer Research Spondyloarthritis Studies and Treatments Inflammatory Bowel Disease CRISPR and Genetic Engineering T-cell and B-cell Immunology vaccines and immunoinformatics approaches Tissue Engineering and Regenerative Medicine Cancer Research and Treatments Dermatology and Skin Diseases Asthma and respiratory diseases Systemic Lupus Erythematosus Research Lymphoma Diagnosis and Treatment Autoimmune and Inflammatory Disorders Research