Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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Food and Chemical Toxicology

Food and Chemical Toxicology is an international multidisciplinary toxicology journal affiliated with the Chinese Society of Toxicology. It publishes original research articles and reviews on toxic effects and toxic mechanisms of natural or synthetic chemicals occurring in food and the human environment, including drugs, consumer chemicals, agricultural products, industrial chemicals, novel foods, biotechnologically derived products, nanomaterials, nutrition-toxicology inter-relationships, and in vitro techniques that foster the 3 Rs.

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Subject Toxicology

Impact Factor 3.5

Quartile Q2

Open Access Type Hybrid

ISSN 0278-6915

eISSN 1873-6351

Invitation Only No

Cost Range USD 4500 APC for open access; no open access publication fee for subscription publication.

Submission Instructions

Food and Chemical Toxicology accepts the following article types. Click on an article type to view submission instructions.

Original Research Articles

Cover Letter A cover letter is required. The cover letter must state that the manuscript is new and original and is not under consideration for publication elsewhere.

Abstract An abstract is required. The abstract must not exceed 200 words. The abstract must be unstructured. The abstract must clearly and briefly identify the novel toxic effect(s) or toxic mechanism(s) being reported and their significance and should briefly state the purpose, principal results, and major conclusions.

Manuscript The manuscript must be divided into clearly defined and numbered sections. Authors must provide 1 to 7 keywords in English, complete the declarations tool, and add a generative AI declaration statement at the end of the manuscript before the references if such tools were used.

References References may be submitted in any consistent style, with in-text citations using author name and year. The reference list should be arranged alphabetically and then chronologically if necessary and include all cited works and only cited works.

Figures & Tables Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures must be supplied as separate files along with the manuscript. Tables must be editable text with captions and all figures and tables must be cited and numbered consecutively in the manuscript text.

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Reviews

Cover Letter A cover letter is required. The cover letter must state that the manuscript is new and original.

Abstract A concise and factual abstract is required. The abstract must not exceed 200 words. The abstract should be unstructured.

Manuscript The manuscript must be divided into clearly defined and numbered sections. The manuscript must include 1 to 7 keywords in English and, if generative AI tools were used in manuscript preparation, a declaration statement in a new section before the references list.

References Citations in the text should use author names and year of publication. The reference list should be arranged alphabetically and then chronologically if necessary.

Figures & Tables Tables must be placed next to the relevant text or on separate page(s) at the end of the article, while figures and other artwork must be supplied as separate files along with the manuscript. Tables must be submitted as editable text rather than images.

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Short Communications

Cover Letter A cover letter is required. Cover letter must state that the manuscript is new and original, and that it is not under consideration for publication elsewhere.

Abstract An abstract is required. Abstract must not exceed 200 words. Abstract must be unstructured and concise enough to stand alone. Abstract must briefly state the purpose of the research, principal results, major conclusions, and clearly and briefly identify the novel toxic effect(s) or toxic mechanism(s) and their significance.

Manuscript Manuscript must be divided into clearly defined and numbered sections. Authors must provide 1 to 7 keywords in English, and if generative AI tools were used in manuscript preparation, a declaration statement must be added at the end of the manuscript in a new section before the references list when first submitted.

References References must use an author-date citation style. Reference list must be arranged alphabetically and then chronologically if necessary, and references at submission may be in any consistent style or format.

Figures & Tables Tables must be placed next to the relevant text or on separate pages at the end of the article, while figures and other artwork must be supplied as separate files along with the manuscript. Tables must be submitted as editable text with captions and all figures and tables must be cited in the manuscript text and numbered consecutively in order of appearance.

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Letters To The Editor

Cover Letter Cover letter must be included. Cover letter must state that the manuscript is new and original.

Abstract A concise and factual abstract must be provided. Abstract must not exceed 200 words.

Manuscript Letters to the Editor are limited to comments on contributions already published in the journal. If generative AI tools were used in manuscript preparation, a declaration statement must be added at the end of the manuscript in a new section before the references list when the paper is first submitted.

References Citations in the text should refer to the author's name and year of publication. Reference list should be arranged alphabetically and then chronologically if necessary.

Figures & Tables Tables must be placed next to the relevant text or on separate pages at the end of the article, and figures must be supplied as separate files along with the manuscript. Tables must be submitted as editable text rather than images, and all figures and tables must be cited in the manuscript text.

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Recent Publications

Update to RIFM fragrance ingredient safety assessment, methyl 3-hydroxyhexanoate, CAS Registry Number 21188-58-9

A.M. Api, A. Bartlett, D. Belsito, D. Botelho, M. Bruze, A. Bryant-Friedrich, G.A. Burton, M.A. Cancellieri, H. Chon, M. Cronin, S. Crotty, M.L. Dagli, W. Dekant, C. Deodhar, K. Farrell, A.D. Fryer, L. Jones, K. Joshi, A. Lapczynski, D.L. Laskin, M. Lavelle, I. Lee, H. Moustakas, J. Muldoon, T.M. Penning, A.H. Piersma, G. Ritacco, N. Sadekar, I. Schember, T.W. Schultz, F. Siddiqi, I.G. Sipes, G. Sullivan, Y. Thakkar

10.1016/j.fct.2026.116202

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The role of p53-mediated signaling pathways in nicotine-induced cancer: a systematic review

Qinhan Jiang, Zhongwei Zhang, Jianming Zhou, Tong Zhou, Huai Wang

10.1016/j.fct.2026.116215

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RIFM fragrance ingredient safety assessment, 3-hexene, 1,1',''-[ethylidynestris(oxy)]tris-, (3Z, 3'Z,3"Z)-, CAS Registry Number 215305-10-5

10.1016/j.fct.2026.116204

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Update to RIFM fragrance ingredient safety assessment, β-guaiene, CAS Registry Number 88-84-6

A.M. Api, A. Bartlett, D. Belsito, D. Botelho, M. Bruze, A. Bryant-Friedrich, G.A. Burton, Cancellieri, H. Chon, M. Cronin, S. Crotty, M.L. Dagli, W. Dekant, C. Deodhar, K. Farrell, A.D. Fryer, L. Jones, K. Joshi, A. Lapczynski, D.L. Laskin, M. Lavelle, I. Lee, H. Moustakas, J. Muldoon, T.M. Penning, A.H. Piersma, G. Ritacco, N. Sadekar, I. Schember, T.W. Schultz, F. Siddiqi, I.G. Sipes, G. Sullivan, Y. Thakkar

10.1016/j.fct.2026.116206

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RIFM fragrance ingredient safety assessment, squalene, CAS Registry Number 111-02-4

10.1016/j.fct.2026.116211

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Frequently asked questions

How long does it take to publish?

1 day from submission to first decision; 34 days from submission to decision after review; 70 days from submission to acceptance; 2 days from acceptance to online publication.

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Is a cover letter required?

Cover letters must be included and must state that the manuscript is new, original, and not under consideration elsewhere. Resubmissions after review must include a separate response letter addressing all editor and reviewer points.

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What are the publication costs?

USD 4500 APC for open access; no open access publication fee for subscription publication.

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Research Topics

Contact Dermatitis and Allergies Pesticide Exposure and Toxicity Animal testing and alternatives Carcinogens and Genotoxicity Assessment Effects and risks of endocrine disrupting chemicals Mycotoxins in Agriculture and Food Phytochemicals and Antioxidant Activities Genomics, phytochemicals, and oxidative stress Heavy Metal Exposure and Toxicity Human auditory perception and evaluation Toxic Organic Pollutants Impact Diverse Scientific and Economic Studies Drug-Induced Hepatotoxicity and Protection Essential Oils and Antimicrobial Activity Educational Robotics and Engineering Antioxidant Activity and Oxidative Stress Biochemical Analysis and Sensing Techniques Pharmacogenetics and Drug Metabolism Natural product bioactivities and synthesis Drug Transport and Resistance Mechanisms Dye analysis and toxicity Trace Elements in Health Immunotoxicology and immune responses Mercury impact and mitigation studies Environmental Toxicology and Ecotoxicology

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