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Geroscience

GeroScience is the official journal of the American Aging Association focused on the biology of aging and the pathophysiology of age-related diseases. It covers biogerontology, neuroscience, cardiovascular research, cancer research, pharmacology, and healthy longevity medicine, prioritizing biomedical research with significant implications for aging and disease mechanisms and aligning with NIA priorities including Alzheimer's disease and vascular cognitive impairment and dementia.

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Subject Geriatrics & Gerontology
Impact Factor 5.4
Quartile Q1
Open Access Type Hybrid
ISSN 2509-2715
eISSN 2509-2723
Invitation Only No
Cost Range Article processing charges (APCs) vary by journal.

Submission Instructions

Geroscience accepts the following article types. Click on an article type to view submission instructions.

Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be 150 to 250 words.
Manuscript Manuscript must be assembled in the order Title Page, Abstract, Text (Introduction, Methods, Results, Discussion), Acknowledgments, Sources of Funding, Disclosures, References, Figure Legends, Tables, and Figures. Manuscript must include 4 to 6 keywords, a disclosure statement, a Declarations or Statements and Declarations section before the references, documentation of any large language model use in the Methods section or another suitable section, and a statement identifying who had the idea for the article, who performed the literature search and data analysis, and who drafted and/or critically revised the work.
References References must be cited in the text using numbers in square brackets and listed consecutively in numerical order by first mention, with only cited published or accepted works included and full DOI links provided when available.
Figures & Tables Tables must be embedded within the manuscript text file, while figures should be submitted separately. Each figure and table must be cited in numerical order in the text, and every figure and table must have a descriptive caption.
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Research Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Research Articles must include an abstract. Abstract must be 150 to 250 words.
Manuscript Manuscript must be assembled as Title Page, Abstract, Text with Introduction, Methods, Results, and Discussion, Acknowledgments, Sources of Funding, Disclosures, References, Figure Legends, Tables, and Figures. Manuscript must include a disclosure statement, 4 to 6 keywords, a Declarations or Statements and Declarations section before the references with applicable headings retained as 'Not applicable' when irrelevant, an author contribution statement, and documentation of any large language model use in the Methods or another suitable section.
References References must be cited by numbers in square brackets. Reference list entries must be numbered consecutively in order of first mention, include only works cited in the text that are published or accepted for publication, and include full DOI links when available.
Figures & Tables Tables must be embedded within the manuscript text file, while figures should be submitted separately. Figures and tables must be cited in numerical order in the text, tables must be numbered with Arabic numerals and have captions, and figure captions must be included in the manuscript text file rather than in the figure files.
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Systematic Reviews

Cover Letter A cover letter is required if unpublished material is included in the manuscript, and it must mention that material to the Editor. The cover letter must mention any unpublished material included in the manuscript.
Abstract An abstract is required. Abstract must be 150 to 250 words.
Manuscript The manuscript must be assembled in the order Title Page, Abstract, Text with Introduction, Methods, Results, and Discussion, Acknowledgments, Sources of Funding, Disclosures, References, Figure Legends, Tables, and Figures, and the title must identify the article as a systematic review or meta-analysis of the literature. The manuscript must include 4 to 6 keywords, a Declarations or Statements and Declarations section before the references with all headings retained and marked 'Not applicable' when irrelevant, author contribution statements, documentation of any large language model use in the Methods or a suitable alternative section, registration information for the systematic review if applicable, and explicit statements of the search strategy, inclusion and exclusion criteria, extracted information characteristics, meta-analysis methods if included, risk of bias across studies, and limitations of the search and analysis.
References References must be cited in numerical order by first mention in the text using numbers in square brackets, and the reference list must be numbered consecutively and include only cited works that have been published or accepted for publication.
Figures & Tables Tables must be embedded within the manuscript text file, while figures should be submitted separately.
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Mini-Reviews

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must be 150 to 250 words.
Manuscript Mini-Reviews should be approximately 3,000 words, excluding references. Manuscript must be assembled in the order Title Page, Abstract, Text (Introduction, Methods, Results, Discussion), Acknowledgments, Sources of Funding, Disclosures, References, Figure Legends, Tables, and Figures. Manuscript must include 4 to 6 keywords and a Declarations or Statements and Declarations section before the references that includes applicable author contribution and AI-use disclosures.
References References must be cited by numbers in square brackets and listed consecutively in numerical order of first mention in the text.
Figures & Tables Mini-Reviews should include 1 to 3 figures and or tables. Tables must be embedded within the manuscript text file, while figures should be submitted separately.
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Recent Publications

Changes in hippocampal volume during a preceding 10-year period do not correlate with cognitive performance and hippocampal blood‒brain barrier permeability in cognitively normal late-middle-aged men

Aftab Bakhtiari, Mark B. Vestergaard, Krisztina Benedek, Birgitte Fagerlund, Erik Lykke Mortensen, Merete Osler, Martin Lauritzen, Henrik B. W. Larsson, Ulrich Lindberg

10.1007/s11357-022-00712-2
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Approximate entropy analysis across electroencephalographic rhythmic frequency bands during physiological aging of human brain

Chiara Pappalettera, Alessia Cacciotti, Lorenzo Nucci, Francesca Miraglia, Paolo Maria Rossini, Fabrizio Vecchio

10.1007/s11357-022-00710-4
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Frailty and functional brain connectivity (FBC) in older adults with mild cognitive impairment (MCI): baseline results from the SYNERGIC Trial

Nick W. Bray, Frederico Pieruccini-Faria, Suzanne T. Witt, Kenneth Rockwood, Robert Bartha, Timothy J. Doherty, Lindsay S. Nagamatsu, Quincy J. Almeida, Teresa Liu-Ambrose, Laura E. Middleton, Louis Bherer, Manuel Montero-Odasso

10.1007/s11357-022-00702-4
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Recapitulation of anti-aging phenotypes by global, but not by muscle-specific, deletion of PAPP-A in mice

Xinna Li, Mary Hager, Madaline McPherson, Michael Lee, Riha Hagalwadi, Mary E. Skinner, David Lombard, Richard A. Miller

10.1007/s11357-022-00692-3
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Rapid emergence of transcriptional heterogeneity upon molecular stress predisposes cells to two distinct states of senescence

Nikolay Burnaevskiy, Junko Oshima, Alexander R. Mendenhall

10.1007/s11357-022-00709-x
View Publication

Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 6 days.

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Is a cover letter required?

A cover letter may be used to mention unpublished material included in the manuscript and to suggest peer reviewers with identifying information such as institutional email address and ORCID or Scopus ID.

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What are the publication costs?

Research Topics

Genetics, Aging, and Longevity in Model Organisms Nutrition and Health in Aging Dementia and Cognitive Impairment Research Frailty in Older Adults Functional Brain Connectivity Studies Epigenetics and DNA Methylation Adipose Tissue and Metabolism Diet and metabolism studies Alzheimer's disease research and treatments Telomeres, Telomerase, and Senescence Neuroinflammation and Neurodegeneration Mechanisms Mitochondrial Function and Pathology Circadian rhythm and melatonin Birth, Development, and Health Balance, Gait, and Falls Prevention Neurological Disease Mechanisms and Treatments Nutritional Studies and Diet Health disparities and outcomes Muscle Physiology and Disorders Health, Environment, Cognitive Aging Gut microbiota and health Tryptophan and brain disorders Dietary Effects on Health Cardiovascular Health and Disease Prevention Advanced Neuroimaging Techniques and Applications

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