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Heart Rhythm O2

Heart Rhythm O2 is an open access companion journal to Heart Rhythm and one of two open access publications of the Heart Rhythm Society. It focuses on cardiac arrhythmias and electrophysiology and publishes original clinical and experimental research, review articles, points-of-view, short reports, commentaries, and letters to the editor. The journal also incorporates content from Cardiovascular Digital Health Journal.

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Subject Cardiac & Cardiovascular Systems
Impact Factor 2.9
Quartile Q2
Open Access Type Open
ISSN 2666-5018
eISSN 2666-5018
Invitation Only Yes
Cost Range USD 2600 APC for all articles, excluding taxes; Society Members receive a 25% discount.

Submission Instructions

Heart Rhythm O2 is an invitation-only journal. Submissions are accepted by invitation from the editorial board only. The following article types are accepted:

Original Clinical

Cover Letter Cover letter is required. Cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract Abstract is required. Abstract must be 250 words or fewer. Abstract must be structured. Abstract must be divided into Background, Objective, Methods, Results, and Conclusion.
Manuscript Manuscript must be 5000 words. Manuscript should be divided into Introduction, Methods, Results, Discussion, and Conclusions, with appropriate subheadings. Manuscript must include 3 to 5 Key Findings submitted as a separate MS Word file and, if generative AI tools were used in manuscript preparation, a section before the references titled 'Declaration of generative AI and AI-assisted technologies in the manuscript preparation process' describing the tool, purpose, and authors’ oversight.
References References must use numbered citations in consecutive order with superscript Arabic numerals. References must be numbered in order of appearance, list the first 6 authors or the first 3 followed by et al. if there are more than 6, and use Index Medicus abbreviations for periodicals.
Figures & Tables Original Clinical articles are limited to 8 figures and tables combined. Figures and legends must be included at the end of the main manuscript MS Word file, and source files of figures, tables, and text graphics are also required. Each figure must have its legend on the same page, each table must be on a separate page, and tables must be numbered consecutively in the order cited.
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Original Experimental

Cover Letter A cover letter is required. Cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract An abstract is required. Abstract must be 250 words or fewer. Abstract must be structured. Abstract must be divided into Background, Objective, Methods, Results, and Conclusion.
Manuscript Manuscript must be 5000 words. Manuscript should be divided into Introduction, Methods, Results, Discussion, and Conclusions, with appropriate subheadings. Manuscript must include 3 to 5 Key Findings submitted as a separate MS Word file and, if generative AI tools were used in manuscript preparation, a section titled 'Declaration of generative AI and AI-assisted technologies in the manuscript preparation process' before the references.
References References must be cited using consecutive superscript Arabic numerals in text and numbered in the reference list in order of appearance, listing the first 6 authors or the first 3 followed by et al. when there are more than 6 authors.
Figures & Tables Figures and tables are limited to 8 combined. Figures and legends must be included at the end of the main manuscript MS Word file, and source files of figures, tables, and text graphics are also required. Each figure must have a caption and tables must be included on separate pages and numbered consecutively in the order cited.
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Topics In Review

Cover Letter Cover letter is required. Cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract Abstract is required. Abstract should be 200 words. Abstract must be unstructured.
Manuscript Manuscript should be 8000 words or fewer. Manuscript must include 3 to 5 Key Findings submitted as a separate MS Word file and, if generative AI tools were used in manuscript preparation, a section titled 'Declaration of generative AI and AI-assisted technologies in the manuscript preparation process' before the references.
References References must use a numbered citation style with consecutive superscript Arabic numerals. References must be numbered in order of appearance, list the first 6 authors or the first 3 followed by et al. if there are more than 6, and use Index Medicus abbreviations for periodicals.
Figures & Tables Topics In Review articles are limited to 8 figures and tables combined. Figures and legends must be included at the end of the main manuscript MS Word file, and source files of figures and tables are also required. Figures must have captions and tables must be numbered consecutively with each table on a separate page.
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Digital Health Technologies And Innovation

Cover Letter A cover letter is required. The cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract Abstract requirements are not specified.
Manuscript Provide 3 to 5 Key Findings as a separate MS Word file and include an AI declaration section before the references if generative AI or AI-assisted technologies were used in manuscript preparation.
References References must be cited with consecutive superscript Arabic numerals in the text and numbered in the reference list in order of appearance, listing the first 6 authors or the first 3 followed by et al. when there are more than 6 authors.
Figures & Tables Figures and legends must be included at the end of the main manuscript MS Word file for review, and source files of figures and tables are also required. Each table must appear on a separate page and figures must be numbered according to their sequence in the text with a caption for each figure.
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Research Letters

Cover Letter Cover letter is required. Cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract Abstract must not be included.
Manuscript Manuscript is limited to 800 words including references and legends. Research Letter must not include headings such as Introduction, Methods, Results, and Conclusions and must include a conclusion statement at the end of the article. Manuscript must include 3 to 5 Key Findings submitted as a separate MS Word file and an AI declaration section before the references if generative AI or AI-assisted technologies were used in manuscript preparation.
References Reference list is limited to a maximum of 5 references. References must be cited numerically in the text using consecutive superscript Arabic numerals and listed in the order of appearance, listing the first 6 authors or the first 3 followed by et al if there are more than 6 authors.
Figures & Tables Research Letter may include up to 1 figure or up to 1 table. Figures and legends must be included at the end of the main manuscript MS Word file, and source files of figures and tables are also required. Supplementary data is not permitted for Research Letters.
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Brief Reports

Cover Letter Cover letter is required. Cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract Abstract must not be included.
Manuscript Manuscript must be under 1500 total words, including references and tables. Manuscript must include 3 to 5 Key Findings submitted as a separate MS Word file, and any use of generative AI in manuscript preparation must be declared in a separate section before the references.
References References must be cited with consecutive superscript Arabic numerals in the order they appear in the text, listed in the same order, list the first 6 authors, and if there are more than 6 authors list the first 3 followed by et al.
Figures & Tables Brief Reports are limited to a combined total of 4 figures and/or tables. Figures and legends must be included at the end of the main manuscript MS Word file, and source files are required whether or not figures are embedded in the text.
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Case Reports

Cover Letter A cover letter is required. The cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract Abstract requirements are not specified.
Manuscript The manuscript must include a separate Declaration of generative AI and AI-assisted technologies in the manuscript preparation process section when applicable and a separate Key Findings file containing 3 to 5 bullet points.
References References must be cited using consecutive superscript Arabic numerals. References must be numbered in the order of appearance, use Index Medicus journal abbreviations, list the first 6 authors or the first 3 followed by et al. when there are more than 6 authors, and exclude unpublished results and personal communications from the reference list.
Figures & Tables Figures and legends must be included at the end of the main manuscript Word file, and source files of figures and tables are also required. Figures must be numbered according to their sequence in the text and tables must be numbered consecutively with each table on a separate page.
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Design Papers

Cover Letter A cover letter is required. The cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract An abstract is required. The abstract must be 250 words or fewer. The abstract must be structured. The abstract must be divided into Background, Objective, Methods, Results, and Conclusion.
Manuscript The manuscript must be 5000 words or fewer. Design Papers should describe proper structures such as DSMB, executive oversight committee, and steering committee, and should provide trial structure and funding. The manuscript must include 5–10 keywords after the abstract, a separate Key Findings file with 3–5 bullet points, and a declaration of generative AI and AI-assisted technologies in the manuscript preparation process before the references if applicable.
References References must be cited numerically as consecutive superscript Arabic numerals in the order they appear, and the reference list must be numbered in that same order with the first 6 authors listed or the first 3 followed by et al. when there are more than 6 authors.
Figures & Tables Design Papers are limited to 8 figures and tables combined. Figures and legends must be included at the end of the main manuscript file, and source files for figures and tables are also required. Each figure must have an editable caption, and tables must be numbered consecutively and placed on separate pages.
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Letters To The Editor

Cover Letter Cover letter is required. Cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract Abstract requirements are not specified.
Manuscript Letters to the Editor must not exceed 400 words excluding the title page. Letters to the Editor may refer to papers published within the previous 6 months and must not contain original data. Manuscript must include 3 to 5 Key Findings submitted as a separate MS Word file and, if generative AI tools were used in manuscript preparation, a separate declaration section before the references using the specified title.
References Letters to the Editor are limited to 10 references. References must be cited as consecutive superscript Arabic numerals, numbered in the reference list in order of appearance, list the first 6 authors, and if there are more than 6 authors list the first 3 followed by et al.
Figures & Tables Letters to the Editor must not contain figures. Figures and legends must be included at the end of the main manuscript MS Word file for review, and source files are required whether or not figures are embedded in the text.
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Replies To The Editor

Cover Letter Cover letter is required. Cover letter must confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the manuscript for submission.
Abstract Abstract is not required.
Manuscript Manuscript must include a separate 'Declaration of generative AI and AI-assisted technologies in the manuscript preparation process' section before the references when generative AI tools were used, and a bulleted Key Findings file containing 3 to 5 items must be submitted separately.
References References must be cited with consecutive superscript Arabic numerals and numbered in the reference list in order of appearance, listing the first 6 authors or, for more than 6 authors, the first 3 followed by et al.
Figures & Tables Figures and legends must be included at the end of the main manuscript MS Word file for review ease, although source files are also required. Each table must be on a separate page, and figures must be numbered according to their sequence in the text with a caption for each illustration.
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Recent Publications

Outflow Tract Premature Ventricular Contractions: Impact of Anatomical Location on Cardiomyopathy Development

Miloud Cherbi, Sebastien Knecht, Rene Tavernier, Mattias Duytschaever, El Mehdi Channan, Nicolas Blankoff, Broes Martens, Maarten A.J. De Smet, Jean-Benoît Le Polain de Waroux

10.1016/j.hroo.2026.08.117
View Publication

Global impedance reduction during pulsed field ablation: implications for impedance-based procedural feedback

Kosuke Onodera, Daiki Kumazawa, Yohei Kikuchi, Keita Yoshiyama, Yosuke Mizuno, Kazuhiro Satomi, Kennosuke Yamashita

10.1016/j.hroo.2026.08.116
View Publication

Evaluation of Esophageal Injury after Very High-Power Short-Duration Pulmonary Vein Isolation Using Late Gadolinium Enhancement MRI

Nikki van Pouderoijen, Elin L.C.H. Stokman, Luuk H.G.A. Hopman, Mark B.M. Hofman, Mark J. Mulder, Michiel J.B. Kemme, Marco J.W. Götte, Cornelis P. Allaart

10.1016/j.hroo.2026.07.034
View Publication

Racial Disparities in Cardiac Implantable Electronic Device Monitoring and Outcomes: The Mediating Role of Consensus-recommended Follow-Up

Jingwen Huang, Rahul Patel, Chang Liu, Michael S. Lloyd

10.1016/j.hroo.2026.08.115
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Long-term performance of VDD vs. VVI ICD leads: a single-manufacturer analysis based on product performance report

Flora D. Gausz, Daniel Fodor, Marton Miklos, Attila Benak, Dora Kranyak, Laszlo Saghy, Tamas Szili-Torok, Mate Vamos

10.1016/j.hroo.2026.07.036
View Publication

Frequently asked questions

How long does it take to publish?

5 days from submission to first decision; 25 days from submission to decision after review; 53 days from submission to acceptance.

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Is a cover letter required?

A cover letter is required to confirm that the manuscript is original and that all authors are responsible for the contents and have read and approved the submission. Fellows Corner submissions should state the fellowship program in the cover letter.

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What are the publication costs?

USD 2600 APC for all articles, excluding taxes; Society Members receive a 25% discount.

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Research Topics

Cardiac Arrhythmias and Treatments Atrial Fibrillation Management and Outcomes Cardiac pacing and defibrillation studies Cardiac electrophysiology and arrhythmias ECG Monitoring and Analysis Cardiovascular Function and Risk Factors Mechanical Circulatory Support Devices Cardiovascular Syncope and Autonomic Disorders Cardiac Structural Anomalies and Repair Cardiovascular Disease and Adiposity Cardiac Valve Diseases and Treatments Heart Rate Variability and Autonomic Control Cardiac Imaging and Diagnostics Cardiovascular Effects of Exercise Microbial Inactivation Methods Heart Failure Treatment and Management Cardiomyopathy and Myosin Studies Pericarditis and Cardiac Tamponade Cardiac Arrest and Resuscitation Healthcare Technology and Patient Monitoring Congenital Heart Disease Studies Venous Thromboembolism Diagnosis and Management Diverse Scientific and Economic Studies Coronary Interventions and Diagnostics Heart rate and cardiovascular health

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