HR

Human Reproduction

Human Reproduction is an ESHRE journal in reproductive medicine published by Oxford University Press. It publishes full length, peer reviewed papers reporting original research, including randomized controlled trials, as well as meta-analyses, opinions, debates, invited editorials, and related content in reproductive biology and medicine.

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Subject Obstetrics & Gynecology, Reproductive Biology
Impact Factor 6.1
Quartile Q1
Open Access Type Hybrid
ISSN 0268-1161
eISSN 1460-2350
Invitation Only No
Cost Range There is usually an Article Processing Charge (APC) for fully open access journals, and hybrid journals usually require an APC for gold open access publication.

Submission Instructions

Human Reproduction accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter A covering letter is required. The covering letter must be addressed to the Editor-in-Chief and state the scientific question asked, the principal new findings, and their significance to the field.
Abstract Abstract requirements are not specified.
Manuscript Manuscripts containing human semen analysis data must include the completed semen analysis checklist or a statement explaining how the methods compare with the Björndahl guidelines.
References References requirements are not specified.
Figures & Tables Figure legends must be provided after file upload, and figures must be uploaded as separate files rather than embedded only in the manuscript. Alt text must be provided in the main manuscript directly under each relevant figure legend for all images, figures, illustrations, and photographs.
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Mini-Reviews

Cover Letter A cover letter is required. Cover letter must be addressed to the Editor-in-Chief and state the scientific question, the principal new findings, and their significance to the field.
Abstract An abstract is required. Abstract must be unstructured and up to 300 words. Abstract must be unstructured.
Manuscript Manuscript text must contain 3000–4000 words excluding references. Text body should be a readable and concise narrative review of the literature, usually under subheadings, and must include a conclusion whose final paragraph summarizes the review themes and identifies unanswered questions for future research. Manuscript must include a graphical abstract, 5–10 keywords immediately after the abstract, a declaration of authors' roles after Acknowledgements and before the Funding statement, and a conflict of interest statement.
References Reference list must contain 50–100 references. References must use an author-date citation style. References must be cited in the text by author and date, listed alphabetically, include up to 10 authors before using et al., list both authors for two-author citations, and use the first author followed by et al. for citations with more than two authors.
Figures & Tables Mini-Reviews may include one or two figures if required. Graphical abstract must be uploaded as a separate file in addition to the main manuscript text file. Figure legends must be self-contained and define all symbols and abbreviations, figures must be numbered consecutively with Arabic numerals and cited sequentially in the text, and the graphical abstract must be a distinct single-panel image with a short legend or title of around 25 words.
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Case Reports

Cover Letter A covering letter is required. Cover letter must be addressed to the Editor-in-Chief and state the scientific question, the principal new findings, and their significance to the field.
Abstract An abstract is required. Abstract must be unstructured.
Manuscript Manuscript should include an introduction, a detailed case description, and a discussion that begins with the principal findings, relates the case to other studies, offers possible explanations, and identifies questions for future research. Manuscript must include up to ten key words, a declaration of authors' roles after Acknowledgements and before the Funding statement, and a conflict of interest statement.
References References must use author-date citations in the text. References must be listed alphabetically, include up to 10 authors before using et al., cite two-author works with both names and works with more than two authors as first author et al., exclude unpublished data from the reference list, and mark accepted but unpublished papers as in press.
Figures & Tables Figures should not exceed the number absolutely necessary. Figures must be uploaded as separate files. Each figure legend must be self-contained and define all symbols and abbreviations used in the figure.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract requirements are not specified.
Manuscript Letters to the Editors must not exceed 1000 words including references. Letters should have a short title, use the form of address “Dear Editors,” include an explanatory note identifying the article discussed, and place the authors at the bottom of the text before the references. Letters must include a Funding section, a conflict of interest statement, author affiliations, and a correspondence section with the corresponding author’s full postal address, email address, and ORCID iD.
References References must be cited in the text by author and date, listed alphabetically, include up to 10 authors before using et al., and use both authors’ names for two-author citations or the first author followed by et al. for works with more than two authors.
Figures & Tables Figures and tables may be included only where absolutely necessary. Tables must be created in Microsoft Word with each data item in a separate cell and a brief descriptive title, and figures must have a self-contained legend defining all symbols and abbreviations.
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Recent Publications

Novel variants in YTHDC2 cause non-obstructive azoospermia by disrupting the mitotic-to-meiotic transition in humans and mice

Aoran Zhi, Ming Li, Muhammad Zubair, Musavir Abbas, Wasim Shah, Abu Mansoor, Fazal Rahim, Imtiaz Ali, Yousaf Raza, Ghulam Murtaza, Nisar Ahmad, Zain Abideen, Hanwei Jiang, Baolu Shi, Huan Zhang, Qinghua Shi

10.1093/humrep/deag086
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Deep immune profiling of endometrial and peripheral blood cells in endometriosis

A Kisovar, M Buttenschoen, Q Obrigewitch, K Powell, P Klenerman, K Zondervan, C M Becker, I E Granne, J H Southcombe

10.1093/humrep/deag090
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Correction to: Revisiting the promise and pitfalls of mitochondrial replacement therapies

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10.1093/humrep/deag092
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A comprehensive review for defining cut-off values of oocyte, zygote, and embryo maturation arrest (OZEMA) due to maternal-effect genes: towards the establishment of clinical criteria

Annelore Van Der Kelen, Özlem Okutman, Munevver Serdarogullari, Bart J H Dequeker, Elodie Javey, Antonio Capalbo, Cecile Lang, Georgia Kakourou, Efthymia Konstantinou, Francesca Mulas, Karen Sermon, Willem Verpoest, Stéphane Viville

10.1093/humrep/deag072
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Third-generation sequencing enables accurate preimplantation genetic testing of monogenic defects for de novo variants and incomplete pedigrees

Yiwei Fang, Yuqian Wang, Yuejuan Zhan, Xiaohui Zhu, Ying Kuo, Nan Wang, Shuo Guan, Shi Song, Mochen Ma, Ying Lian, Jin Huang, Xu Zhi, Ping Liu, Rong Li, Zhiqiang Yan, Jie Qiao, Liying Yan

10.1093/humrep/deag082
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Frequently asked questions

How long does it take to publish?

Rapid rate of peer review and publication.

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Is a cover letter required?

A covering letter is required for each manuscript submission and should be addressed to the Editor-in-Chief, stating the scientific question asked, the principal new findings, and their significance to the field.

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What are the publication costs?

There is usually an Article Processing Charge (APC) for fully open access journals, and hybrid journals usually require an APC for gold open access publication.

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Research Topics

Reproductive Biology and Fertility Ovarian function and disorders Reproductive Health and Technologies Assisted Reproductive Technology and Twin Pregnancy Sperm and Testicular Function Reproductive System and Pregnancy Endometriosis Research and Treatment Prenatal Screening and Diagnostics Gynecological conditions and treatments Ectopic Pregnancy Diagnosis and Management Uterine Myomas and Treatments Pregnancy and preeclampsia studies Reproductive Health and Contraception Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities Hypothalamic control of reproductive hormones Ovarian cancer diagnosis and treatment Sexual Differentiation and Disorders Pluripotent Stem Cells Research Menopause: Health Impacts and Treatments Birth, Development, and Health Reproductive Physiology in Livestock Preterm Birth and Chorioamnionitis Demographic Trends and Gender Preferences Diverse Scientific and Economic Studies Testicular diseases and treatments

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