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JCO Precision Oncology

JCO Precision Oncology is an ASCO journal focused on precision oncology research and publishes article categories including original reports, review articles, case reports, commentaries, editorials, and special articles.

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Subject Oncology
Impact Factor 5.6
Quartile Q1
Open Access Type Open
eISSN 2473-4284
Invitation Only No
Cost Range No submission fee and no publication fee for JCO Precision Oncology. Open Access fees vary by corresponding author location and license selected; ASCO members receive a 10% discount.

Submission Instructions

JCO Precision Oncology accepts the following article types. Click on an article type to view submission instructions.

Original Reports

Cover Letter A cover letter is required. The cover letter must describe the significance and uniqueness of the work, note any similar work previously reported by the authors, and mention any prior correspondence with the journal about the manuscript.
Abstract A structured abstract is required. The abstract must be 275 words. The abstract must be structured. The abstract must use the headings PURPOSE, PATIENTS AND METHODS or a similar methods heading, RESULTS, and CONCLUSION.
Manuscript Original Reports are limited to 3,000 words, although initial submission may exceed this limit by up to 1,000 words. The abstract must be placed after the title page. Original Reports require a Context Summary, and for JCO Precision Oncology it must be fewer than 150 words and include the headings Key objective, Knowledge generated, and Relevance.
References References must be numbered in the order in which they are cited in the text.
Figures & Tables Original Reports are limited to 6 figures and tables. Tables must be placed at the end of the manuscript. Figure legends must be included in the manuscript file, and extended patient demographic data must be included in a table rather than in the text.
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Review Articles

Cover Letter A cover letter is required. The cover letter must describe the work's significance and uniqueness and note any prior correspondence with the journal about the manuscript.
Abstract An abstract is required. The abstract must be 275 words. Systematic reviews, consensus guidelines, and meta-analyses must use a structured abstract, while other Review Articles must use an unstructured abstract. Structured abstracts must use the headings PURPOSE, DESIGN, RESULTS, and CONCLUSION.
Manuscript Review Articles are limited to 4,000 words, although initial submission may exceed this limit by no more than 1,000 words. Review Articles must provide an unbiased and comprehensive perspective on previously published work in an area of clinical relevance and should be disease-focused, examine new data in the field, and describe applications to practice. The abstract must be placed after the title page, and an optional graphical abstract consisting of one graphical abstract per manuscript may be included at revision.
References Review Articles are limited to 150 references. References must be numbered in the order in which they are cited in the text.
Figures & Tables Review Articles are limited to 6 figures and tables. Tables must be placed at the end of the manuscript. Figure legends must be included in the manuscript file, and tables must be cited in the order in which they appear in the text using Arabic numerals.
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Case Reports

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work, note any similar work previously reported by the authors, and include any prior correspondence about the manuscript.
Abstract Abstract must not be included.
Manuscript Manuscript is limited to 1,500 words. Case report should provide a brief overview of the case and a concise literature review. Case report must be supported by data, provide access to primary data, and include the variant, platform, and targeted therapy used.
References References are limited to 20. References must be numbered in the order in which they are cited in the text.
Figures & Tables Figures and tables are limited to 3 total. Tables must be placed at the end of the manuscript. Figure legends must be included in the manuscript file.
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Correspondence

Cover Letter A cover letter is required. Cover letter must describe the significance and uniqueness of the work and note any prior correspondence with the journal about the manuscript.
Abstract Abstract must not be included.
Manuscript Correspondence is limited to 750 words, although initial submission may exceed this limit by no more than 1,000 words.
References Correspondence is limited to 10 references. References must be numbered in the order in which they are cited in the text, and letters responding to a JCO article must include the reference to that article.
Figures & Tables Tables must be placed at the end of the manuscript, and figure legends must be included in the manuscript file.
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Special Articles

Cover Letter A cover letter is required with the submission. Cover letter must describe the significance and uniqueness of the work and note any prior correspondence about the manuscript.
Abstract An abstract is required. Abstract must not exceed 275 words. Abstract must be structured. Abstract must use the headings PURPOSE, PATIENTS AND METHODS or a similar methods heading, RESULTS, and CONCLUSION.
Manuscript Manuscript is limited to 4,000 words, although initial submission may exceed this limit by no more than 1,000 words. Abstract must be placed after the title page. Funding sources and the methods used to select guideline committee membership must be explicitly stated, and the processes for deliberation must be clearly described and free of bias.
References References must be numbered in the order in which they are cited in the text.
Figures & Tables Special Articles are limited to a combined total of 6 figures and tables. Tables must be placed at the end of the manuscript. Figure legends must be included in the manuscript file.
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Recent Publications

Validation of LOH-Germline Inference Calculator of Variant Origin on Real-World Data of Prevalence of Germline and Somatic BRCA1/2 Mutations in High-Grade Serous Ovarian Cancer in Serbia

Katarina Živić, Ivana Boljević, Milana Matović, Milica Nedeljković, Ana Krivokuća, Radmila Janković, Miljana Tanić

10.1200/po-25-00819
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Human Epidermal Growth Factor Receptor 2 Quantification Using Computational Pathology to Identify Novel Biomarkers for Trastuzumab Deruxtecan–Treated Human Epidermal Growth Factor Receptor 2–Positive Gastric Cancer

Ansh Kapil, Henrik Failmezger, Yu Fu, Andreas Spitzmüller, Jessica Chan, Susanne Haneder, Anatoliy Shumilov, Alice Barkell, Toshihiro Oguma, Koichiro Inaki, Fumitaka Suto, John Allard, Jeeyun Lee, Arthur W. Lambert, Markus Schick, J. Carl Barrett, Günter Schmidt, Hadassah Sade, Mark Gustavson, Danielle Carroll, Fabiola Cecchi

10.1200/po-25-00823
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Unleashing Precision Oncology in the Development of Human Epidermal Growth Factor Receptor 2–Targeted Antibody Drug Conjugates for Urothelial Carcinoma

Bradley A. McGregor, Guru P. Sonpavde

10.1200/po-26-00110
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Use of ALK Inhibitors in Patients With Nonlung Malignancies Bearing ALK Alteration Prolongs Treatment Duration

Vitor Abreu de Góes, Matthew Lee, Miguel Zugman, Ali Moradi, Salvador Jaime-Casas, Koral Shah, Yu Jun Li, Daniela V. Castro, Xiaochen Li, Benjamin Mercier, Joann Hsu, Alexander Chehrazi-Raffle, Vicki Doctor, Amber Moran, Maurie Markman, Aditya Shreenivas, Sumanta Kumar Pal

10.1200/po-26-00121
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Systematic Review: Prognostic Molecular Biomarkers in Wilms Tumors

Agustina Oller, Patrick Kemmeren, Daniela Perotti, Harm van Tinteren, Arnauld Verschuur, Filippo Spreafico, Jesper Brok, Rhoikos C.J. Furtwängler, Tanzina Chowdhury, Reem Al-Saadi, Gordan M. Vujanic, Amy L. Treece, Jarno Drost, Martine van Grotel, Elizabeth A. Mullen, Nicholas F. Evageliou, Norbert Graf, Andrew L. Hong, Manfred Gessler, James I. Geller, Marry M. van den Heuvel-Eibrink

10.1200/po-25-01017
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Frequently asked questions

How long does it take to publish?

Rapid Review initial peer review is typically completed within 72 hours of reviewer assignment, with a first editorial decision rendered shortly thereafter. Certain accepted Rapid Review manuscripts in JCO may post online 5 days after acceptance. Simultaneous publication inquiries must be received at least two months before the meeting date.

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Is a cover letter required?

A cover letter is required with each new manuscript submission. It must describe the significance of the work, its uniqueness, any similar prior work by the authors, and any prior correspondence with the journal, and it should be addressed to the Editor-in-Chief of the relevant journal.

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What are the publication costs?

JCO Precision Oncology has no submission fee and no publication fee. Optional Open Access fees vary by corresponding author location and license selected, and ASCO members receive a 10% discount.

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Research Topics

Cancer Genomics and Diagnostics Lung Cancer Treatments and Mutations Genetic factors in colorectal cancer BRCA gene mutations in cancer Cancer Immunotherapy and Biomarkers Lung Cancer Research Studies Colorectal Cancer Treatments and Studies PARP inhibition in cancer therapy Prostate Cancer Treatment and Research Pancreatic and Hepatic Oncology Research Genomics and Rare Diseases HER2/EGFR in Cancer Research Melanoma and MAPK Pathways Cancer Cells and Metastasis Prostate Cancer Diagnosis and Treatment Breast Cancer Treatment Studies Sarcoma Diagnosis and Treatment DNA Repair Mechanisms Neuroblastoma Research and Treatments Lung Cancer Diagnosis and Treatment Advanced Breast Cancer Therapies Cholangiocarcinoma and Gallbladder Cancer Studies Statistical Methods in Clinical Trials Glioma Diagnosis and Treatment Neuroendocrine Tumor Research Advances

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