Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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Journal of Hepatology publishes original papers, reviews, case reports and letters to the editor in hepatology. The journal is published in English, supplements may be accepted after editorial review, and full text is available online through institutional access and the journal website.
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Subject
Gastroenterology & Hepatology
Impact Factor
33
Quartile
Q1
Open Access Type
Hybrid
ISSN
0168-8278
eISSN
1600-0641
Invitation Only
No
Cost Range
Submission and publication are free of charge; optional open access fee is US $5320 after acceptance; uninvited Letters to the Editor have a €50 submission fee effective November 15th 2025; fast-track handling requires a submission fee.
Submission Instructions
Journal of Hepatology accepts the following article types. Click on an article type to view submission instructions.
Original Manuscripts
Cover Letter
Cover Letter requirements are not specified.
Abstract
A structured abstract is required for Original Manuscripts. Abstract must not exceed 275 words. Abstract must be structured using the headings Background & Aims, Methods, Results, and Conclusions. Abstract must use the headings Background & Aims, Methods, Results, and Conclusions.
Manuscript
Original Manuscripts must not exceed 6000 words including the abstract, references, tables, and figure legends. Manuscript must be arranged as Title page, Abstract, Impact and Implications, Introduction, Materials and methods or Patients and methods, Results, Discussion, Abbreviations, Acknowledgements, References, Tables, Figure legends, and Figures. Manuscript must include Impact and Implications of 3 to 4 sentences, a methods section highlighting key methods, 3 to 12 keywords on the title page, an author contributions statement and AI declaration before the references if applicable, and revised Original Manuscripts must include 3 to 5 highlights submitted in a separate editable file with each bullet no longer than 85 characters including spaces.
References
Original Manuscripts must not exceed 100 references. References must be ordered as they appear in the text, include article titles, include all authors unless there are more than three in which case the first three are followed by et al., and web references must include the full URL and access date.
Figures & Tables
Original Manuscripts may include a maximum of 8 tables and/or figures. Tables must be included as a separate section at the end of the manuscript, figure legends must be listed in the text document separate from the figure files, and figures are uploaded separately. Figure legends must not exceed 100 words.
Review Articles
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must not exceed 275 words. Abstract does not need to be structured.
Manuscript
Review article text must not exceed 5000 words. Manuscript order is title page, abstract, impact and implications, introduction, materials and methods or patients and methods, results, discussion, abbreviations, acknowledgements, references, tables, figure legends, and figures. Review articles should include 5 to 10 key points, 3 to 4 Impact and Implications sentences, 3 to 12 keywords on the title page, and an AI-use declaration before the references if generative AI was used.
References
Review articles must not exceed 150 references. References must be numbered in the order cited in the text, include article titles, list all authors unless there are four or more in which case only the first three are followed by et al., and web references must include the full URL and access date.
Figures & Tables
Review articles should include no more than 8 tables and/or colored figures. Tables must appear as a separate section at the end of the manuscript, and figure legends must be included in the text document separate from the figure files.
Case Reports
Cover Letter
Cover Letter requirements are not specified.
Abstract
Abstract must not exceed 275 words. Abstract does not need to be structured.
Manuscript
Manuscript must not exceed 3000 words. Manuscript order is Title page, Abstract, Impact and Implications, Introduction, Materials and methods or Patients and methods, Results, Discussion, Abbreviations, Acknowledgements, References, Tables, Figure legends, and Figures. Manuscript must include 3 to 4 sentences of Impact and Implications, 3 to 12 keywords on the title page, and an AI-use declaration before the references if generative AI was used in manuscript preparation.
References
References must not exceed 10. References must be ordered as they appear in the text, include article titles, cite all listed references in the text, list all authors unless there are more than three, and for four or more authors list the first three followed by et al.
Figures & Tables
A combined total of tables and figures must not exceed 2. Tables must appear as a separate section at the end of the manuscript and figure legends must be included in the text document separate from the figure files. Figure legends must not exceed 100 words.
Letters To The Editor
Cover Letter
Cover Letter requirements are not specified.
Abstract
Letters To The Editor do not require a structured abstract. Letters To The Editor must not exceed 800 words. Letters To The Editor do not require a structured abstract.
Manuscript
Letters To The Editor must not exceed 800 words. Keywords are not required for Letters To The Editor.
References
Letters To The Editor must not exceed 10 references. References must be ordered as they appear in the text, include article titles, cite all listed references in the text, and list the first three authors followed by et al. when there are four or more authors.
Figures & Tables
Letters To The Editor may include a maximum of 1 table or figure. Tables must be included as a separate section at the end of the manuscript, and figure legends must be listed in the text document separate from the figure files.
Recent Publications
Listen to EASL's new Podcast series "Talk Liver to Me"!
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10.1016/s0168-8278(26)02669-3
View Publication
Applications for the EASL Schools 2027 close on 28 September. Discover them!
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10.1016/s0168-8278(26)02667-x
View Publication
MICROB-PREDICT works on identifying microbiome-based predictors and mechanisms of decompensated liver cirrhosis & ACLF, and develop personalised treatment strategies. Discover the project!
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10.1016/s0168-8278(26)02670-x
View Publication
Submit your application for the Mobility / Research Fellowship Programme by 1 September!
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10.1016/s0168-8278(26)02668-1
View Publication
Frequently asked questions
How long does it take to publish?
Median time from submission to first decision is 5 days.
Reformat to Journal of Hepatology using Livewrite PremiumIs a cover letter required?
A cover letter is required for revised manuscripts and should state that the manuscript has been revised according to the comments of the editor and reviewers. A separate point-by-point response to reviewers must be included with the covering letter.
Reformat to Journal of Hepatology using Livewrite PremiumWhat are the publication costs?
Submission and publication are free of charge. Authors may choose optional open access after acceptance for US $5320. Uninvited Letters to the Editor carry a €50 submission fee effective November 15th 2025.
Reformat to Journal of Hepatology using Livewrite PremiumResearch Topics
Liver Disease Diagnosis and Treatment
Hepatitis C virus research
Hepatitis B Virus Studies
Liver Disease and Transplantation
Liver Diseases and Immunity
Hepatocellular Carcinoma Treatment and Prognosis
Liver physiology and pathology
Organ Transplantation Techniques and Outcomes
Hepatitis Viruses Studies and Epidemiology
Drug-Induced Hepatotoxicity and Protection
Systemic Lupus Erythematosus Research
Alcohol Consumption and Health Effects
Diet, Metabolism, and Disease
Drug Transport and Resistance Mechanisms
Pediatric Hepatobiliary Diseases and Treatments
Diabetes and associated disorders
Diet and metabolism studies
Cholangiocarcinoma and Gallbladder Cancer Studies
HIV/AIDS drug development and treatment
Pancreatic function and diabetes
Metabolism and Genetic Disorders
Pancreatitis Pathology and Treatment
Gallbladder and Bile Duct Disorders
Immune Cell Function and Interaction
Cancer, Hypoxia, and Metabolism