Overview Submission Instructions Recent Publications Frequently Asked Questions Research Topics

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npj Breast Cancer

npj Breast Cancer is a journal in the npj Series focused on breast cancer research and published in partnership with the Breast Cancer Research Foundation.

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Subject Oncology

Impact Factor 7.6

Quartile Q1

Open Access Type Open

eISSN 2374-4677

Invitation Only No

Cost Range Authors pay an article processing charge (APC); APC details and discretionary waiver information are provided via the journal's article processing charges page.

Submission Instructions

npj Breast Cancer accepts the following article types. Click on an article type to view submission instructions.

Article

Cover Letter A cover letter is required. The cover letter must include the corresponding author's affiliation and contact information and briefly explain the context, importance, and journal suitability of the work.

Abstract An abstract is required. The abstract must be no longer than 150 words. The abstract must be unstructured with no subheadings.

Manuscript The manuscript must include Introduction, Results, Discussion, and Methods sections, with no subheadings in the Introduction or Discussion and subheadings used in the Results and Methods. The manuscript must include Data availability, Author contributions, and Competing Interests sections, place all Methods in the main manuscript file rather than Supplementary Information, declare funding in the Acknowledgments section with no separate Funding statement, and document any use of a large language model in the Methods or another suitable section.

References References are limited to 60. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance and list all authors unless there are more than five, in which case only the first author should be given followed by 'et al.'.

Figures & Tables Figure legends are limited to 350 words per figure. For initial submission, figures should be inserted within the text at appropriate positions, although figure files may also be uploaded separately. Multi-panel figures should be presented on a single page with each panel labeled using an a), b), c) convention.

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Review

Cover Letter A cover letter is required. The cover letter should include the corresponding author’s affiliation and contact information and briefly explain the context, importance, and journal fit of the work.

Abstract An abstract is required. The abstract must be no more than 70 words. The abstract must be unstructured with no subheadings.

Manuscript The main text is typically 3,000–4,000 words in length. Subheadings are permitted in the main text. An Author contributions statement and a Competing Interests statement are mandatory, and any use of a large language model must be documented in the Methods section or another suitable manuscript section if no Methods section is available.

References References are limited to 60. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance, list all authors unless there are more than five authors in which case only the first author followed by 'et al.' should be given, and include only one publication per reference number.

Figures & Tables Figure files can be provided in the manuscript or uploaded separately. Multi-panel figures should be presented on a single page with panels labeled a), b), c), and figure legends are limited to 350 words per figure.

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Brief Communication

Cover Letter A cover letter is required with the submission. The cover letter should include the corresponding author's affiliation and contact information and briefly explain the context, importance, and journal fit of the work.

Abstract An abstract is required. The abstract must be no more than 70 words. The abstract must be unstructured with no subheadings.

Manuscript The main text should be 1,000–1,500 words, excluding the abstract, methods, references, and figure legends. The main text must have no subheadings, while the Methods section should use subheadings. The manuscript must include Data availability, Author contributions, and Competing Interests statements, and any use of a large language model must be documented in the Methods section or another suitable section if no Methods section is available.

References Brief Communications should include around 20 references as a guide. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance, and all authors should be listed unless there are more than five, in which case the first author should be followed by 'et al.'.

Figures & Tables Figure files may be included in the manuscript or uploaded separately. Multi-panel figures should be presented on a single page with panels labeled a), b), c), and figure legends must not exceed 350 words per figure.

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Case Report

Cover Letter A cover letter is required. The cover letter should include the corresponding author's affiliation and contact information and briefly explain the context, importance, and journal fit of the submission.

Abstract An abstract is required. Abstract must be no more than 150 words. The abstract must be unstructured with no subheadings.

Manuscript The manuscript should include an Introduction without subheadings, a Results section with subheadings, a Discussion without subheadings and without limitations or conclusions sections, and a Methods section with subheadings. The manuscript must include a Data availability section and an Author contributions statement listing each author individually by initials, and any use of a large language model must be disclosed in the Methods or another suitable section if no Methods section is present.

References Case Reports should include around 50 references as a guide. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance, include all authors unless there are more than five in which case the first author is followed by 'et al.', and only one publication may be assigned to each reference number.

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Recent Publications

Machine learning-based identification of high-risk triple-negative breast cancer patients despite pathological complete response after neoadjuvant chemotherapy

Koen Kwakkenbos, Nadine S. van den Ende, Bernadette A. M. Heemskerk-Gerritsen, Jifke F. Veenland, Agnes Jager, Carolien H. M. van Deurzen

10.1038/s41523-026-00979-0

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Neighborhood deprivation and oncotype DX recurrence scores among Black and White women: the interplay between race, place, and tumor biology

Jasmine M. Miller-Kleinhenz, Lauren E. Barber, Maret L. Maliniak, Lindsay J. Collin, Demetria J. Smith-Graziani, Jeffery M. Switchenko, Kevin C. Ward, Lauren E. McCullough

10.1038/s41523-026-00978-1

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Platinum-based neoadjuvant chemotherapy and the predictive role of DNA damage response biomarkers in TNBC: the NeoCarbo study

Eriseld Krasniqi, Anna Di Benedetto, Lorena Filomeno, Teresa Arcuri, Cristiana Ercolani, Gianluigi Ferretti, Simona Gasparro, Alberto Fulvi, Arianna Roselli, Loretta D’Onofrio, Laura Pizzuti, Maddalena Barba, Marcello Maugeri-Saccà, Claudio Botti, Franco Graziano, Ilaria Puccica, Sonia Cappelli, Fabio Pelle, Flavia Cavicchi, Amedeo Villanucci, Ida Paris, Tatiana D’Angelo, Fabio Calabrò, Sandra Rea, Roy De Vita, Letizia Perracchio, Giuseppe Sanguineti, Silvia Takanen, Laura Marucci, Lucia Goanta, Laura Greco, Ramy Kayal, Pina Tiziana Falbo, Paola Scavina, Matteo Vergati, Marco Mazzotta, Nicola Calonaci, Mauro Minelli, Giuliana D’Auria, Giulio Caravagna, Giovanni Blandino, Patrizia Vici

10.1038/s41523-026-00977-2

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Preoperative onapristone-XR in postmenopausal women with progesterone receptor-positive (PgR+)/HER2-negative early breast cancer: SOLTI-1802 ONAWA trial results

Meritxell Bellet, Juan M. Ferrero-Cafiero, Milana Bergamino Sirvén, Claudette Falato, Xavier González, Kepa. Amillano, Nuria Chic, Serafin Morales, Ariadna Gasol, Paolo Nuciforo, Guillermo Villacampa, Patricia Villagrasa, Caroline H. Diep, Davis Seelig, Carol Lange, Antonio D’Assoro, Aleix Prat, Tomás Pascual, Cristina Saura

10.1038/s41523-025-00887-9

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Potential treatment targets in the whole-tissue proteome of triple negative breast cancer

Tram B. Doan, Merridee A. Wouters, Jiashu Hu, Jennifer M. S. Koh, Erin K. Sykes, Clare Loudon, Zainab Noor, Nirmala Pathmanathan, Jane E. Armes, Peter G. Hains, Phillip J. Robinson, Qing Zhong, Roger R. Reddel, J. Dinny Graham, Rosemary L. Balleine

10.1038/s41523-026-00976-3

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Frequently asked questions

How long does it take to publish?

Median time from submission to first editorial decision is 10 days. Median time from submission to acceptance is 156 days.

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Is a cover letter required?

Authors should provide a cover letter that includes the affiliation and contact information for the corresponding author, briefly explains the context and importance of the work and why it is appropriate for the journal, and may include confidential information, related work, and suggested or excluded referees.

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What are the publication costs?

Authors pay an article processing charge (APC) for the final published article to be open access online and freely accessible. Discretionary APC waivers are available.

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Research Topics

Breast Cancer Treatment Studies Cancer Genomics and Diagnostics HER2/EGFR in Cancer Research Advanced Breast Cancer Therapies Cancer Cells and Metastasis Cancer Immunotherapy and Biomarkers BRCA gene mutations in cancer Breast Lesions and Carcinomas Cancer-related Molecular Pathways Cancer Risks and Factors Estrogen and related hormone effects Cancer Treatment and Pharmacology Global Cancer Incidence and Screening Radiomics and Machine Learning in Medical Imaging AI in cancer detection PARP inhibition in cancer therapy DNA Repair Mechanisms Immunotherapy and Immune Responses Single-cell and spatial transcriptomics Monoclonal and Polyclonal Antibodies Research Chronic Lymphocytic Leukemia Research Genetic factors in colorectal cancer Brain Metastases and Treatment Lung Cancer Treatments and Mutations Metabolism, Diabetes, and Cancer

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