Overview
Submission Instructions
Recent Publications
Frequently Asked Questions
Research Topics
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AO
Archives of Pathology & Laboratory Medicine is a monthly, peer-reviewed medical journal of the College of American Pathologists. Published since 1926, it is an official CAP publication focused on pathology and laboratory medicine, and online access to full-text and PDF articles is free.
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Impact Factor
3.2
Quartile
Q2
Open Access Type
Open
ISSN
0003-9985
eISSN
1543-2165
Invitation Only
No
Submission Instructions
Archives of Pathology & Laboratory Medicine accepts the following article types. Click on an article type to view submission instructions.
Original Articles
Cover Letter
A cover letter is required. Cover letter must list all author names, degrees, and affiliations; identify the single corresponding author; note any affiliation changes, meeting presentation details, and financial support.
Abstract
A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Context, Objective, Design, Results, and Conclusions.
Manuscript
Manuscript must not exceed 50 double-spaced text pages. Manuscript must include a title page and a Materials and Methods section, and Original Articles must consist of original research. If artificial intelligence tools were used to create the manuscript, their use and the specific tools must be disclosed in the Materials and Methods section.
References
References must not exceed 60. References must follow AMA style. References must be numbered in order of first mention, cited as superscript Arabic numerals, not alphabetized, and list up to 6 authors or editors before using the first 3 followed by "et al."
Figures & Tables
Original Articles may include no more than 16 figures and 2 tables. Figures must be uploaded directly into the online submission system, and tables must be provided as separate pages in the manuscript file. Figures must be numbered in citation order and arranged into composite images when there are at least 4 figures, and tables must be numbered in citation order and include a descriptive title.
Review Articles
Cover Letter
Cover Letter requirements are not specified.
Abstract
A structured abstract is required for Review Articles. Abstract must not exceed 250 words. Abstract must be structured under the headings Context, Objective, Data Sources, and Conclusions. Abstract headings must be Context, Objective, Data Sources, and Conclusions.
Manuscript
Manuscript must not exceed 50 double-spaced text pages.
References
Review Articles must include no more than 80 references. References must follow AMA style. References must be numbered in order of citation, cited as superscript Arabic numerals, not alphabetized, use Index Medicus journal abbreviations, and list up to 6 authors or editors before using the first 3 followed by "et al.".
Figures & Tables
Review Articles must include no more than 16 figures and 2 tables. Figure files must be uploaded directly into the online submission system, and tables must be provided on separate pages.
Reports Of The Results Of Meta-Analyses
Cover Letter
Cover letter is required. Cover letter must list all author names, academic degrees, and affiliations; specify the single corresponding author; note any post-study affiliation changes, meeting presentation details, and financial support for the research.
Abstract
Abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Context, Objective, Data Sources, Study Selection, Data Extraction, and Conclusions.
Manuscript
If artificial intelligence tools were used to create the manuscript, their use and the specific tools must be disclosed in the Materials and Methods section.
References
References must follow AMA style. References must be numbered in order of mention, cited with superscript Arabic numerals, not alphabetized, use Index Medicus journal abbreviations, list up to 6 authors/editors or the first 3 followed by "et al." if more than 6, include the issue number after the volume, and provide a DOI for online publications when possible.
Figures & Tables
For manuscripts containing at least 4 figures, the figures must be arranged into composite image(s). Figures must be uploaded directly into the online submission system, while tables and figure legends must appear on separate pages in the manuscript file. Figures and tables must be numbered in the order cited in the text, tables must include a descriptive title, and table abbreviations or acronyms must be defined in a footnote.
Letters To The Editor
Cover Letter
Cover letter must list all author names, academic degrees, and affiliations, identify a single corresponding author, note any changed affiliations, provide meeting presentation details if applicable, and acknowledge financial support.
Abstract
Abstract is not required for Letters To The Editor.
Manuscript
Letters To The Editor must be limited to 500 words or fewer. Letters To The Editor must be prepared in the same manner as a manuscript. If artificial intelligence tools were used in creating the manuscript, their use and the specific tools must be disclosed in the Materials and Methods section.
References
Letters To The Editor may include no more than 10 pertinent references. References must follow AMA style. References must be numbered in order of first mention using superscript Arabic numerals, not alphabetized, with journal names abbreviated according to Index Medicus and author lists showing up to 6 names or the first 3 followed by "et al." when there are more than 6.
Figures & Tables
Figure files must be uploaded separately into the online submission system, and tables must appear on separate pages. Tables must be double-spaced, numbered in citation order, and given descriptive titles.
Consensus Statements
Cover Letter
A cover letter is required. The cover letter must list all author names, degrees, and affiliations, identify the single corresponding author, note any affiliation changes, provide meeting presentation details if applicable, and acknowledge financial support.
Abstract
A structured abstract is required. The abstract must not exceed 250 words. The abstract must be structured. The abstract headings must be Objective, Participants, Evidence, Consensus Process, and Conclusions.
Manuscript
If artificial intelligence tools were used to create the manuscript, their use and the specific tools must be disclosed in the Materials and Methods section.
References
References must follow AMA style. References must be numbered in order of first mention using superscript Arabic numerals, not alphabetized, use Index Medicus journal abbreviations, and list up to 6 authors or editors before using 3 followed by et al.
Figures & Tables
If a manuscript contains 4 or more figures, they must be arranged into composite images. Figure files must be uploaded separately through the submission system, while tables must be provided on separate pages in the manuscript file. Figures and tables must be numbered in the order cited, tables must include a descriptive title, and table abbreviations or acronyms must be defined in a footnote.
Recent Publications
Interobserver Variability Across Whole-Slide Imaging Systems
Benzion Samueli, Hikmat Al-Ahmadie, Marina Baine, Melissa Pulitzer, Marc Rosenblum, Emaan Alvi, Harshita Mehrotra, Elisabet Pujadas, Dan Carlucci, Kaitlyn Gelfant, Ali Manzo, Lisette Spencer, Julia Stetsyk, Jacob Dreiher, Victor E. Reuter, Meera Hameed, Orly Ardon
10.5858/arpa.2025-0449-oa
View Publication
Perspectives on Neuroendocrine and Mixed Neuroendocrine Neoplasms of the Pancreas
Claudio Luchini, Michelle D. Reid
10.5858/arpa.2026-0067-ed
View Publication
Pathology Fellowship Trends From 2015 to 2024: More Openings but Less Interest
Reem O. Ahmed, Roxanne Sandhu, Nat Pernick, Debra L. Zynger
10.5858/arpa.2025-0511-le
View Publication
Cogitations of a Computational Pathologist: Artificial or Computational—Rethinking Intelligence in the Age of Algorithms
Giovanni M. Luján
10.5858/arpa.2025-0558-ed
View Publication
Interpretive Diagnostic Error Reduction: Guideline Update from the College of American Pathologists in Collaboration With the Association of Directors of Anatomic and Subspecialty Pathology
Suzanne M. Dintzis, Juanita J. Evans, Marisol Hernandez, Tanja Kalicanin, Christina Lacchetti, Raouf E. Nakhleh, Christopher N. Otis, Liron Pantanowitz, Vinita Parkash, Stephen S. Raab
10.5858/arpa.2026-0016-cp
View Publication
Research Topics
Clinical Laboratory Practices and Quality Control
Sarcoma Diagnosis and Treatment
Lymphoma Diagnosis and Treatment
AI in cancer detection
Breast Lesions and Carcinomas
Breast Cancer Treatment Studies
Cervical Cancer and HPV Research
Cancer and Skin Lesions
Cancer Genomics and Diagnostics
Salivary Gland Tumors Diagnosis and Treatment
Lung Cancer Treatments and Mutations
Neuroendocrine Tumor Research Advances
Pancreatic and Hepatic Oncology Research
Soft tissue tumor case studies
Viral-associated cancers and disorders
HER2/EGFR in Cancer Research
Vascular Tumors and Angiosarcomas
Medical Imaging and Pathology Studies
Genetic factors in colorectal cancer
Urologic and reproductive health conditions
Renal cell carcinoma treatment
Ovarian cancer diagnosis and treatment
Tumors and Oncological Cases
Urinary and Genital Oncology Studies
Molecular Biology Techniques and Applications
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