AO

Archives of Pathology & Laboratory Medicine

Archives of Pathology & Laboratory Medicine is a monthly, peer-reviewed medical journal of the College of American Pathologists. Published since 1926, it is an official CAP publication focused on pathology and laboratory medicine, and online access to full-text and PDF articles is free.

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Subject Medical Laboratory Technology, Medicine, Research & Experimental, Pathology
Impact Factor 3.2
Quartile Q2
Open Access Type Open
ISSN 0003-9985
eISSN 1543-2165
Invitation Only No

Submission Instructions

Archives of Pathology & Laboratory Medicine accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter A cover letter is required. Cover letter must list all author names, degrees, and affiliations; identify the single corresponding author; note any affiliation changes, meeting presentation details, and financial support.
Abstract A structured abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Context, Objective, Design, Results, and Conclusions.
Manuscript Manuscript must not exceed 50 double-spaced text pages. Manuscript must include a title page and a Materials and Methods section, and Original Articles must consist of original research. If artificial intelligence tools were used to create the manuscript, their use and the specific tools must be disclosed in the Materials and Methods section.
References References must not exceed 60. References must follow AMA style. References must be numbered in order of first mention, cited as superscript Arabic numerals, not alphabetized, and list up to 6 authors or editors before using the first 3 followed by "et al."
Figures & Tables Original Articles may include no more than 16 figures and 2 tables. Figures must be uploaded directly into the online submission system, and tables must be provided as separate pages in the manuscript file. Figures must be numbered in citation order and arranged into composite images when there are at least 4 figures, and tables must be numbered in citation order and include a descriptive title.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required for Review Articles. Abstract must not exceed 250 words. Abstract must be structured under the headings Context, Objective, Data Sources, and Conclusions. Abstract headings must be Context, Objective, Data Sources, and Conclusions.
Manuscript Manuscript must not exceed 50 double-spaced text pages.
References Review Articles must include no more than 80 references. References must follow AMA style. References must be numbered in order of citation, cited as superscript Arabic numerals, not alphabetized, use Index Medicus journal abbreviations, and list up to 6 authors or editors before using the first 3 followed by "et al.".
Figures & Tables Review Articles must include no more than 16 figures and 2 tables. Figure files must be uploaded directly into the online submission system, and tables must be provided on separate pages.
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Reports Of The Results Of Meta-Analyses

Cover Letter Cover letter is required. Cover letter must list all author names, academic degrees, and affiliations; specify the single corresponding author; note any post-study affiliation changes, meeting presentation details, and financial support for the research.
Abstract Abstract is required. Abstract must not exceed 250 words. Abstract must be structured. Abstract must use the headings Context, Objective, Data Sources, Study Selection, Data Extraction, and Conclusions.
Manuscript If artificial intelligence tools were used to create the manuscript, their use and the specific tools must be disclosed in the Materials and Methods section.
References References must follow AMA style. References must be numbered in order of mention, cited with superscript Arabic numerals, not alphabetized, use Index Medicus journal abbreviations, list up to 6 authors/editors or the first 3 followed by "et al." if more than 6, include the issue number after the volume, and provide a DOI for online publications when possible.
Figures & Tables For manuscripts containing at least 4 figures, the figures must be arranged into composite image(s). Figures must be uploaded directly into the online submission system, while tables and figure legends must appear on separate pages in the manuscript file. Figures and tables must be numbered in the order cited in the text, tables must include a descriptive title, and table abbreviations or acronyms must be defined in a footnote.
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Letters To The Editor

Cover Letter Cover letter must list all author names, academic degrees, and affiliations, identify a single corresponding author, note any changed affiliations, provide meeting presentation details if applicable, and acknowledge financial support.
Abstract Abstract is not required for Letters To The Editor.
Manuscript Letters To The Editor must be limited to 500 words or fewer. Letters To The Editor must be prepared in the same manner as a manuscript. If artificial intelligence tools were used in creating the manuscript, their use and the specific tools must be disclosed in the Materials and Methods section.
References Letters To The Editor may include no more than 10 pertinent references. References must follow AMA style. References must be numbered in order of first mention using superscript Arabic numerals, not alphabetized, with journal names abbreviated according to Index Medicus and author lists showing up to 6 names or the first 3 followed by "et al." when there are more than 6.
Figures & Tables Figure files must be uploaded separately into the online submission system, and tables must appear on separate pages. Tables must be double-spaced, numbered in citation order, and given descriptive titles.
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Consensus Statements

Cover Letter A cover letter is required. The cover letter must list all author names, degrees, and affiliations, identify the single corresponding author, note any affiliation changes, provide meeting presentation details if applicable, and acknowledge financial support.
Abstract A structured abstract is required. The abstract must not exceed 250 words. The abstract must be structured. The abstract headings must be Objective, Participants, Evidence, Consensus Process, and Conclusions.
Manuscript If artificial intelligence tools were used to create the manuscript, their use and the specific tools must be disclosed in the Materials and Methods section.
References References must follow AMA style. References must be numbered in order of first mention using superscript Arabic numerals, not alphabetized, use Index Medicus journal abbreviations, and list up to 6 authors or editors before using 3 followed by et al.
Figures & Tables If a manuscript contains 4 or more figures, they must be arranged into composite images. Figure files must be uploaded separately through the submission system, while tables must be provided on separate pages in the manuscript file. Figures and tables must be numbered in the order cited, tables must include a descriptive title, and table abbreviations or acronyms must be defined in a footnote.
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Recent Publications

Tumors of the Genitourinary System Associated With Mutations in the Tricarboxylic Acid Cycle

Xiaoyang Liu, Douglas M. Dahl, Chin-Lee Wu

10.5858/arpa.2025-0575-ra
View Publication

Assessment of Distributive DNA Methylation Profiling for Central Nervous System Tumor Classification Between Laboratories in the United States and Brazil

Larissa V. Furtado, Nickhill Bhakta, Gustavo R. Teixeira, Flavia E. de Paula, Dhwani Trivedi, Alex Breuer, Mohammed Kanchwala, Motomi Mori, Jiaming Li, Chad Blackshear, David Wilkins, Leticia G. C. Santos, Luciane S. da Silva, Luiz F. Lopes, Carlos Rodriguez-Galindo, Rui M. Reis, David W. Ellison

10.5858/arpa.2026-0018-oa
View Publication

Tumor Cell-Free DNA Assay Analytical Performance in 101 Clinical Laboratories Participating in a College of American Pathologists Proficiency Testing Program

Christina M. Lockwood, Venkata Yellapantula, Jonathan M. Tsai, Rhona J. Souers, Patricia Vasalos, Kelly Devereaux, Rondell P. Graham, Meera Hameed, Neal Lindeman, Jason D. Merker, Mark Routbort, Rena R. Xian, Joel T. Moncur

10.5858/arpa.2025-0635-cp
View Publication

Histologic Patterns That Hinder Detection of Cirrhosis on Routine Abdominal Imaging: Steatosis, Centrizonal Sinusoidal Fibrosis, and Biliary-type Cirrhosis

Nazire E. Albayrak, Chien-Kuang Cornelia Ding, Eric D. Nguyen, Sergio Grosu, Hsuan-Hwai Lin, Francis Yao, Linda D. Ferrell, Sarah E. Umetsu, Benjamin M. Yeh, Kwun Wah Wen

10.5858/arpa.2025-0534-oa
View Publication

Atrophic Patterns and Enterochromaffin-Like Cell Hyperplasia in Collagenous Gastritis: Diagnostic Overlap With Autoimmune Atrophic Gastritis

Chao Fan, Noam Harpaz, Qingqing Liu

10.5858/arpa.2026-0013-oa
View Publication

Research Topics

Clinical Laboratory Practices and Quality Control Sarcoma Diagnosis and Treatment Lymphoma Diagnosis and Treatment AI in cancer detection Breast Lesions and Carcinomas Breast Cancer Treatment Studies Cervical Cancer and HPV Research Cancer and Skin Lesions Cancer Genomics and Diagnostics Salivary Gland Tumors Diagnosis and Treatment Lung Cancer Treatments and Mutations Neuroendocrine Tumor Research Advances Pancreatic and Hepatic Oncology Research Soft tissue tumor case studies Viral-associated cancers and disorders HER2/EGFR in Cancer Research Vascular Tumors and Angiosarcomas Medical Imaging and Pathology Studies Genetic factors in colorectal cancer Urologic and reproductive health conditions Renal cell carcinoma treatment Ovarian cancer diagnosis and treatment Tumors and Oncological Cases Urinary and Genital Oncology Studies Molecular Biology Techniques and Applications

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