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Cancer Science

Cancer Science is one of the oldest oncology journals in the world and has stimulated cancer research since 1907. It publishes research on molecular mechanisms of cancer development, with emphasis on innovative cancer treatment including molecular targeted therapy and immunotherapy based on genomic abnormalities of individual cancers and the tumor microenvironment.

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Subject Oncology
Impact Factor 4.3
Quartile Q2
Open Access Type Open
ISSN 1347-9032
eISSN 1349-7006
Invitation Only No
Cost Range APC: $2,600 USD / £1,650 GBP / €2,350 EUR; 61% discount for society members; 20% discount for Associate Editors; APC waived for Meeting Report.

Submission Instructions

Cancer Science accepts the following article types. Click on an article type to view submission instructions.

Original Article

Cover Letter A covering letter must be attached to the submission. Cover letter must state that the manuscript is submitted for consideration, quantify each author's contribution, confirm all authors meet authorship criteria and agree with the manuscript, provide corresponding author contact details, include a concise paragraph on salient and novel findings, specify one subject category, state any prior brief abstract presentation, disclose whether reproduced tables or figures are included or write n/a, and explain any unavoidable word-count excess.
Abstract Original Article manuscripts must include an abstract. Abstract must be no more than 250 words. Abstract structure is not explicitly specified. Abstract must state the purpose, basic procedures, main findings, and principal conclusions of the study.
Manuscript Original Article manuscripts may be up to 5000 words excluding references, with the title page, abstract or summary, and figure legends included in the word count. Manuscript must follow the structure Introduction, Material and Methods, Results, and Discussion. Manuscript must include an author contributions section, five MeSH key words below the abstract in alphabetical order, a summary of no more than 250 words, and transparent disclosure of any AI tool use in the Methods or Acknowledgements section.
References References must follow Vancouver style. References must be numbered consecutively in order of appearance, cited in the text with Arabic superscript numerals, and use journal title abbreviations conforming to Chemical Abstracts practice.
Figures & Tables The number of tables and figures is not limited for Original Article manuscripts. Figures and tables must be uploaded separately. Each figure must have an accompanying legend, and reproduced figures or tables must carry appropriate credit in the legend.
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Review Article

Cover Letter A covering letter must be attached to the submission. The covering letter must state that the paper is submitted for consideration, has not been published or submitted elsewhere except as a brief abstract if applicable, quantify each author's contribution, confirm all authors contributed significantly and agree with the manuscript, provide corresponding author contact details, include a concise paragraph of salient and novel findings, specify one subject category, explain any unavoidable word-count excess, and state whether reproduced tables or figures are included or write n/a.
Abstract Review Article manuscripts must include an abstract. The abstract must be no more than 250 words. The abstract must be unstructured.
Manuscript Review Article manuscripts must be 4000-5000 words, and the word count includes the title page, abstract, references, and figure legends. The manuscript text must use the subheadings Introduction, Materials and Methods, Results, and Discussion. The manuscript must include five MeSH keywords below the abstract in alphabetical order, a Conflict of Interest statement, and transparent AI-use disclosure in the Methods or Acknowledgements section if AI was used.
References Review Article manuscripts may include up to 80 references. References must follow Vancouver style. References must be numbered consecutively in order of appearance and cited in the text with Arabic superscript numerals, with journal title abbreviations conforming to Chemical Abstracts practice.
Figures & Tables Review Article manuscripts may include 4-6 tables or figures in total. Figures and tables must be uploaded separately. Figure legends must be provided in a separate section after the references, and figures and tables must be numbered consecutively in Arabic numerals.
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Report

Cover Letter A covering letter must be attached to the submission. The cover letter must state submission for consideration, confirm all authors meet authorship criteria and agree with the manuscript, quantify each author's contribution, provide corresponding author contact details, include a concise paragraph on salient and novel findings, specify one subject category, explain any unavoidable word-count excess, and disclose whether reproduced tables or figures are included with permission or state n/a if not applicable.
Abstract Report manuscripts must include an abstract. The abstract must not exceed 250 words. The abstract structure is not explicitly specified beyond inclusion requirements. The abstract has no explicitly required headings.
Manuscript Report manuscripts must be up to 2000 words, and the title page, abstract, references, and figure legends are included in this word count. Report manuscripts must include Results and Discussion sections, which may be combined, and Acknowledgements. Five key words selected from MeSH must appear below the abstract in alphabetical order, AI tool use if any must be described in the Methods or Acknowledgements section, and the title page must give the precise word count including references.
References Report manuscripts may include up to 25 references. References must follow Vancouver style. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals.
Figures & Tables Report manuscripts may include up to 4 tables or figures in total. Figures and tables must be uploaded separately. Figure legends must be included in the manuscript and count toward the word limit.
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Case Report

Cover Letter A covering letter is required. Cover letter must state that all authors meet authorship criteria, quantify each author’s contribution, provide corresponding author contact details, include a concise paragraph on the salient and novel findings, specify one subject category, explain any unavoidable word-count excess, indicate whether reproduced tables or figures are included or state n/a, and for Case Reports state that consent for publication in print and electronically was obtained from the patient or next of kin.
Abstract An abstract is required. Abstract must not exceed 100 words. Abstract structure is not explicitly specified. Abstract must be followed by five MeSH key words in alphabetical order.
Manuscript Manuscript must be up to 2000 words, with the title page, abstract, references, and figure legends included in the word count. Text must use the subheadings Introduction, Materials and Methods, Results, and Discussion. Manuscript must include five key words below the abstract in alphabetical order selected from MeSH, an AI-use disclosure in the Methods or Acknowledgements section if applicable, and a statement in the text that consent for publication in print was obtained from the patient or next of kin.
References References may include up to 25 entries. References must follow Vancouver style. References must be numbered consecutively in order of appearance and cited in the text with Arabic superscript numerals.
Figures & Tables Case Reports may include up to 3 tables or figures in total. Figures and tables must be uploaded separately. Figure legends must be provided in a separate section after the references.
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Letter To The Editor

Cover Letter A covering letter must be attached to the submission. Cover letter must state that the paper is submitted for consideration, quantify each author's contribution, include corresponding author contact details, provide a concise paragraph of salient and novel findings, specify one subject category, state if the paper was submitted as a brief abstract, confirm all authors meet authorship criteria, contributed significantly, and agree with the manuscript content, report whether reproduced tables or figures are included and permissions obtained or state n/a, and explain any unavoidable word-count excess.
Abstract Abstract requirements are not specified.
Manuscript Letter To The Editor manuscripts must be up to 1000 words, and the title page, abstract, references, and figure legends are included in the word count. Letter To The Editor manuscripts must include five key words below the abstract in alphabetical order selected from MeSH, and any AI tool use must be described transparently and in detail in the Methods or Acknowledgements section.
References Letter To The Editor manuscripts may include 10 references. References must follow Vancouver style. References must be numbered consecutively in order of appearance and cited in the text using Arabic superscript numerals, with journal title abbreviations conforming to Chemical Abstracts practice.
Figures & Tables Letter To The Editor manuscripts may include up to 3 figures or tables in total. Figures and tables must be uploaded separately. The title page must give the precise word count including references.
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Recent Publications

Transporter‐Associated Therapeutic Efficacy of an SMVT ‐Targeted Boron Carrier in Boron Neutron Capture Therapy

Kenichiro Eza, Kohei Tsujino, Rina Shidoh‐Kazuki, Yoshiki Fujikawa, Hideki Kashiwagi, Gen Futamura, Ryo Hiramatsu, Toshihiro Takami, Masahiko Wanibuchi, Naonori Hu, Hiroki Tanaka, Minoru Suzuki, Kai Nishimura, Shota Tanaka, Hiroyuki Nakamura, Shinji Kawabata

10.1111/cas.70444
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Ketogenic Diet and β‐Hydroxybutyrate Suppress Bladder Cancer Growth and Enhance Anti‐ PD ‐ L1 Immunotherapy Efficacy

Yuan Zeng, Gangli Gu, Lin Yang, Bohao Fan, Haochen Cui, Lei Yan, Zhao Liu

10.1111/cas.70447
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Bile‐Derived Exosomal miR ‐196a/‐196b as Diagnostic Biomarkers Associated With Tumor Progression in Biliary Tract Cancer

Naotaka Kugiyama, Katsuya Nagaoka, Takehisa Watanabe, Michihiro Yoshida, Tadashi Toyohara, Cheng Pan, Kenyu Hashimoto, Fumiya Otsuka, Shinya Ushijima, Yukiko Uramoto, Hajime Iwasaki, Motohiro Yoshinari, Shunpei Hashigo, Kazuki Hayashi, Itaru Naitoh, Fumihiro Okumura, Hiromu Kondo, Kaiki Anbe, Hiromitsu Hayashi, Yoshihiro Komohara, Yasuhito Tanaka

10.1111/cas.70443
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Combined MEK1/2 and Autophagy Inhibition Suppresses Tumor Growth via STING‐Mediated Type I Interferon Response in iCCA

Chengqiang Sun, Zheng Gao, Enfu Dong, Liangxia Ding, Shanru Feng, Jiafeng Chen, Pascal Kwangwari, Yinghong Shi, Weiren Liu, Xin Zhang, Ao Huang, Jian Zhou, Sheng Wang, Jia Fan, Xiutao Fu, ZhenBin Ding

10.1111/cas.70436
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Ezh2 Inhibits the Differentiation of Short‐Lived Effector CD8 + T Cells and Promotes T Cell‐Dependent Antitumor Immunity

Kenji Takagi, Junpei Suzuki, Yuko Matsuoka, Makoto Kuwahara, Taro Oshikiri, Masakatsu Yamashita

10.1111/cas.70439
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Frequently asked questions

How long does it take to publish?

Submission to first decision (median): 8 days; submission to acceptance (median): 116 days; acceptance to publication (median): 14 days.

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Is a cover letter required?

A covering letter should be attached. It should declare exclusive submission, confirm all authors meet authorship criteria and agree with the manuscript, provide corresponding author contact details, summarize salient and novel findings, specify one subject category, explain any word-count overage, include rationale for multiple corresponding authors if applicable, and confirm patient consent for Case Reports.

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What are the publication costs?

APC: $2,600 USD / £1,650 GBP / €2,350 EUR. Society members receive 61% off, Associate Editors receive 20% off, and Meeting Report articles are waived.

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Research Topics

RNA modifications and cancer Epigenetics and DNA Methylation Cancer Cells and Metastasis Cancer-related molecular mechanisms research Cancer Immunotherapy and Biomarkers Cancer, Hypoxia, and Metabolism Immunotherapy and Immune Responses Lung Cancer Treatments and Mutations Cancer-related gene regulation Cancer-related Molecular Pathways Immune Cell Function and Interaction Cancer Genomics and Diagnostics MicroRNA in disease regulation Pancreatic and Hepatic Oncology Research Peptidase Inhibition and Analysis Immune cells in cancer Genetic factors in colorectal cancer Lymphoma Diagnosis and Treatment RNA Research and Splicing CAR-T cell therapy research Ubiquitin and proteasome pathways Angiogenesis and VEGF in Cancer DNA Repair Mechanisms Cancer Research and Treatments Glycosylation and Glycoproteins Research

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