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Digestion

Digestion is the International Journal of Gastroenterology. It concentrates on clinical research reports and includes editorials and reviews, with coverage of stomach/esophagus, bowel, neurogastroenterology, liver/bile, pancreas, metabolism/nutrition, and gastrointestinal oncology. The journal publishes work on human physiology, metabolic studies, and clinical research on the etiology, diagnosis, and therapy of human diseases, with relevance for gastroenterologists and clinicians in related fields.

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Subject Gastroenterology & Hepatology
Impact Factor 3.6
Quartile Q2
Open Access Type Closed
ISSN 0012-2823
eISSN 1421-9867
Invitation Only No
Cost Range Institutional and personal subscription rates are listed by region and format, including online access, print only, and combined online and print options.

Submission Instructions

Digestion accepts the following article types. Click on an article type to view submission instructions.

Research Article

Cover Letter The cover letter should describe the gap in knowledge that the manuscript addresses.
Abstract An abstract is required. The abstract must be structured. The abstract must use the headings Introduction, Methods, Results, and Conclusion.
Manuscript A Research Article is typically 5000 words in length. The manuscript must include Introduction, Methods, Results, and Discussion sections. The manuscript must include a short title for the running head, 3–5 keywords, a Statement of Ethics section, a Conflict of Interest Statement, a Funding Sources section, an Author Contributions section, a Data Availability Statement, and required statements after the main body text and before the reference list.
References Vancouver References must be cited sequentially in the text using Arabic numerals in square brackets and listed numerically in the order cited, with only cited publications included in the reference list.
Figures & Tables A Research Article typically includes 4 to 8 tables and figures. Figures and tables must be uploaded as separate items in their original file format, with the manuscript text, tables, and figures submitted as separate files. Figures and tables must include legends, figure references must use 'Figure' in text and 'Fig.' in parentheses or legends, and tables should be prepared in MS Word.
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Review Article

Cover Letter The cover letter should describe the gap in knowledge that the manuscript addresses.
Abstract Required. Structured. Background, Summary, and Key Messages.
Manuscript Review Articles must contain Acknowledgement, Conflict of Interest Statement, Funding Sources, and Author Contributions sections after the main body of the text and before the reference list. Review Articles must include a critical discussion of the reported data, a clear conclusion with potential impacts on the standard of care, 3–5 keywords, and declarations required for conflicts of interest, funding, and author contributions.
References Numerical. References must be cited sequentially using Arabic numerals in square brackets, listed only if cited in the text, arranged in citation order, and include no more than 6 authors per reference followed by et al. if there are more than 6.
Figures & Tables Figures and tables must be uploaded as separate items in their original file format. Figure legends must be included in the format "Fig. 1. Legend text." and figures mentioned in text must use "Figure" outside parentheses and "Fig." inside parentheses.
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Systematic Review

Cover Letter The cover letter should describe the gap in knowledge that the manuscript addresses.
Abstract required structured Introduction, Methods, Results, and Conclusion.
Manuscript Systematic Reviews should be presented in the Introduction, Methods, Results, Discussion format. Systematic Reviews must provide 3–5 keywords and include statements for ethics, conflict of interest, funding sources, author contributions, and data availability, and they must clearly declare any use of generative AI-based tools.
References References in the text must be numbered sequentially in square brackets, and the reference list must contain only cited publications arranged in numerical order.
Figures & Tables Figures and tables must be uploaded as separate items in their original file format. Systematic Reviews must include a flow chart either in the text or in online supplementary material, and figures should be referred to as Figure or Fig. according to placement in the text.
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Brief Report

Cover Letter A cover letter is required. The cover letter should describe the gap in knowledge that the manuscript addresses.
Abstract An abstract is required. The abstract should be short. The abstract must be structured. The abstract must use the headings Introduction, Methods, Results, and Conclusion.
Manuscript A Brief Report is typically 3000 words in length. Brief Reports should follow the same structure as full-length Research Articles and must include Introduction, Methods, Results, and Discussion sections. Brief Reports must include 3–5 keywords, a Statement of Ethics, a Conflict of Interest Statement, Funding Sources, an Author Contributions section, and a Data Availability Statement.
References References should be cited sequentially using Arabic numerals in square brackets. The reference list must include only cited publications and be arranged numerically in the order cited.
Figures & Tables A Brief Report may include up to 3 tables and figures. Figures and tables must be uploaded as separate items in their original file format. Figure legends must be included, figures mentioned in the text without round brackets must be written as Figure, and figures mentioned in round brackets or in legends must be abbreviated as Fig.
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Guidelines

Cover Letter The cover letter should describe the gap in knowledge that the manuscript addresses.
Abstract Abstract requirements are not specified.
Manuscript Guidelines are typically 5000 words in length. Guidelines should describe the clinical problem to be addressed, should include a statements section after the main body of the text and before the reference list, and should declare any use of generative AI tools and provide an Author Contribution Statement, a Conflict of Interest Statement, and a Funding Sources statement.
References References in the text should be identified sequentially using Arabic numerals in square brackets, and the reference list should include only cited publications and be arranged numerically in citation order.
Figures & Tables Guidelines may include up to 3 tables and figures. Figures and tables must be submitted as separate files. Tables must be uploaded as separate items in their original file format, and figures and tables should follow the journal's separate-file submission requirements.
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Recent Publications

Dynamic Changes in Circulating and Tissue Biomarkers and Therapeutic Response to HER2/PD-1 Dual Blockade in HER2-Positive Gastric Cancer

Yueyan Shi, Jie Zhang, Jianmei Gu, Wenjing Zhao, Guoxing Li, Xiaohua He

10.1159/000553654
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Extraintestinal manifestations have a negative impact on Quality of Life of patients with Inflammatory Bowel Disease

Jesus K. Yamamoto-Furusho, Fausto Damian Gutierrez-Herrera

10.1159/000553638
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Directional Bias in Polyp Detection during Colonoscopy: A Prospective Observational Study

Atsushi Katagiri, Sayaka Mizuno, Daichi Mori, Yoshinao Onishi, Yuta Yamazaki, Kensuke Higuchi, Norihiro Suzuki, Kazuo Kikuchi, Shinya Nakatani, Takahisa Fujiwara, Kazuya Inoki, Kenichi Konda, Masayuki Tojo, Kunihiko Wakamura, Hitoshi Yoshida

10.1159/000552207
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Prospective validation of magnified endoscopic examination with image-enhanced endoscopy as an optical biopsy for differentiating superficial duodenal epithelial tumor and non-neoplastic lesion in duodenum

Atsushi Nakayama, Yoko Kubosawa, Daisuke Minezaki, Kohei Morioka, Kentaro Iwata, Kurato Miyazaki, Teppei Masunaga, Yukie Hayashi, Mari Mizutani, Teppei Akimoto, Yusaku Takatori, Noriko Matsuura, Tomohisa Sujino, Kaoru Takabayashi, Naohisa Yahagi, Motohiko Kato

10.1159/000552784
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Accurate imaging diagnosis of small pancreatic carcinoma/high-grade pancreatic intraepithelial neoplasia using combined indirect imaging findings

Ryota Sagami, Kazuhiro Mizukami, Hidefumi Nishikiori, Hiroaki Tsuji, Takao Sato, Yoshifumi Azuma, Yasuhisa Hiroshima, Koshiro Tsutsumi, Masahide Fukuda, Sotaro Ozaka, Kensuke Fukuda, Mie Arakawa, Masao Iwao, Ryo Ogawa, Yuka Hirashita, Takuro Uchida, Mizuki Endo, Masaaki Kodama, Shin-ichiro Horiguchi, Tsutomu Daa, Tatsunori Satoh, Kazuhito Honda, Kazunari Murakami

10.1159/000552273
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Frequently asked questions

How long does it take to publish?

Accepted papers are published online within a few days of acceptance. Proof corrections are requested within 48 hours.

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Is a cover letter required?

A cover letter is required and should describe the knowledge gap, significance, fit to the journal scope, and unique contribution; special issue or article collection submissions should identify the collection and inviter where relevant.

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What are the publication costs?

Subscription pricing is listed for institutional, personal, and society member access in CHF, EUR, and USD by region; online access, print only, and combined online and print options are available.

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Research Topics

Helicobacter pylori-related gastroenterology studies Gastrointestinal motility and disorders Diverse Scientific and Economic Studies Gastroesophageal reflux and treatments Pancreatitis Pathology and Treatment Inflammatory Bowel Disease Human auditory perception and evaluation Liver Disease Diagnosis and Treatment Gastric Cancer Management and Outcomes Microscopic Colitis Neuroendocrine Tumor Research Advances Eosinophilic Esophagitis Esophageal Cancer Research and Treatment Neuropeptides and Animal Physiology Pancreatic and Hepatic Oncology Research Colorectal Cancer Screening and Detection Liver Disease and Transplantation Legal Cases and Commentary Diet and metabolism studies Clinical Nutrition and Gastroenterology Digestive system and related health Pancreatic function and diabetes Esophageal and GI Pathology Gastrointestinal disorders and treatments Gallbladder and Bile Duct Disorders

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