IR

Intestinal Research

Intestinal Research is a quarterly journal focused on inflammatory bowel disease and related gastroenterology topics. It publishes review articles and original articles, has print ISSN 1598-9100 and online ISSN 2288-1956, and reports an impact factor of 3.9 in Gastroenterology & Hepatology.

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Subject Gastroenterology & Hepatology
Impact Factor 3.9
Quartile Q2
Open Access Type Open
ISSN 1598-9100
eISSN 1598-9100
Invitation Only No
Cost Range Individual subscription: USD 10 per issue or USD 40 annually; institutional subscription: USD 12 per issue or USD 48 annually.

Submission Instructions

Intestinal Research accepts the following article types. Click on an article type to view submission instructions.

Original Article

Cover Letter Cover letter is required. Cover letter must state that the material has not been published previously or submitted elsewhere and must disclose any potential conflict of interest.
Abstract Abstract is required. Abstract must be structured and contain 200–250 words, with a maximum of 250 words. Abstract must be structured. Abstract headings must be Background/Aims, Methods, Results, and Conclusions, and it must be followed immediately by 3–5 keywords.
Manuscript Manuscript must be organized as title page, abstract including keywords, introduction, methods, results, discussion, references, tables, figure legends, and figures. Manuscript must include 3–5 MeSH-style keywords after the abstract, state sources of funding, and disclose any use of generative AI in the manuscript with explicit description in Methods when the study examines or relies on generative AI.
References References must use numbered superscript citations in order of first appearance, consistent with Vancouver-style numbering. References must be listed in numerical order, list all authors when there are 6 or fewer and the first 3 followed by et al. when there are more than 6, use official or Medline journal abbreviations, and place authors’ last names before initials.
Figures & Tables Tables must be included in the main manuscript on separate pages, while figures must be uploaded as separate files and not embedded in the main body file. Figures must be numbered in order of citation, submitted as separate original files, and color images must have resolution of at least 300 dpi, while tables must be numbered in order of appearance and placed on separate pages with titles above them.
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Review

Cover Letter Cover letter is required and must state that the submission has not been published previously or submitted elsewhere. Cover letter must state that the submission has not been published previously or submitted elsewhere.
Abstract Abstract is required for Review articles. Abstract must be 150–200 words. Abstract should be unstructured.
Manuscript Manuscript should include the section headings Abstract, Introduction, Main Text, Conclusions, Acknowledgments, References, Tables, and Figure legends. Manuscript must include 3–5 keywords immediately after the abstract, and all Reviews must state sources of funding.
References References must be cited in the text with Arabic numeral superscripts in order of appearance and listed in numerical order, with all authors listed for six or fewer authors and the first three followed by "et al." for more than six.
Figures & Tables Tables must be included in the main manuscript file on separate pages, whereas figures must be uploaded as separate files and not embedded in the manuscript. Tables must be numbered in order of appearance and have concise titles above them, and figures must be numbered in order cited with legends provided on a separate page.
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Case Report

Cover Letter Cover letter is required and must state that the material has not been previously published or submitted elsewhere and disclose any potential conflict of interest. Cover letter must state that the material has not been previously published or submitted elsewhere and disclose any potential conflict of interest.
Abstract Abstract is required. Abstract must be unstructured and 150–200 words. Abstract must be unstructured.
Manuscript Manuscript must be arranged as title page, abstract, keywords, main body with Introduction, Case Report, and Discussion, references, tables, figure legends, and figures. Manuscript must include 3–5 MeSH-style keywords immediately after the abstract, separated by semicolons.
References References must not exceed 20. References must be numbered serially in order of citation, all must be cited in the text as superscripts, journal titles must use official abbreviations, references with no more than seven authors must list all authors, and references with more than six authors must list the first three followed by 'et al.'.
Figures & Tables Figures must be uploaded as separate original files and not embedded in the manuscript, while tables are included with the manuscript. Figures should include helpful illustrations and be less than 8 cm wide, and all figures must have titles.
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Statement

Cover Letter Cover letter is required. Cover letter must state that the material has not been published previously or submitted elsewhere and must disclose any potential conflict of interest.
Abstract Abstract is required. Abstract must be no more than 250 words.
Manuscript Statement format and structure must follow those of Review articles and present a tight linear argument rather than a mini-review. Manuscript must include 3–5 keywords immediately after the abstract and must openly disclose any use of generative AI tools.
References References must be cited as superscript Arabic numerals in order of appearance and listed numerically, with all authors listed for six or fewer authors and the first three followed by et al. for more than six.
Figures & Tables Tables must be included in the main manuscript file on separate pages, while figures must be uploaded as separate files and not embedded in the main body file. Tables and figures must be numbered in the order cited, each table must have a concise title above it, and figure legends must be provided in English on a separate page.
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Letter To The Editor

Cover Letter Cover letter must include statements that the submission has not been published previously or submitted elsewhere and must disclose any potential conflict of interest. Cover letter must state that the material has not been published previously or submitted elsewhere and must disclose any potential conflict of interest.
Abstract Abstract is not required for Letter To The Editor manuscripts.
Manuscript Manuscript may be organized in the sequence of title, main text not divided into separate sections, references, tables, and figures.
References References must not exceed 10. Citations must use Arabic numerals as superscripts in order of appearance, and references must be listed numerically with up to 6 authors named in full or the first 3 followed by et al. if there are more than 6.
Figures & Tables Tables and figures combined must not exceed 3 in total. Tables must be included in the main document, each on a separate page, while figures must be submitted as separate files and not embedded in the main body file. Tables must be numbered in order of appearance and have concise titles above them.
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Brief Communication

Cover Letter Cover letter is required. Cover letter must state that the material has not been published previously or submitted elsewhere and must disclose any potential conflict of interest.
Abstract Abstract is not required.
Manuscript Manuscript may be organized in the sequence of title, main text not divided into separate sections, references, tables, and figures.
References References must not exceed 10. Citations must use Arabic numeral superscripts in order of appearance, and references must be listed numerically with all authors listed for 6 or fewer authors or the first 3 followed by et al. for more than 6.
Figures & Tables Tables and figures combined must not exceed 3 in total. Tables must be included in the main manuscript file, and figures must be submitted as separate files rather than embedded in the main body file.
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Recent Publications

Real-world efficacy and safety of upadacitinib in difficult-to-treat Crohn’s disease: a 24-week multicenter study from China

Zile Zhang, Shuowen Zhang, Wensong Ge, Yue Li, Ruidong Chen, Wen Tang, Qunying Wang, Yihong Fan, Linyan Zhou, Feng Tian, Chunxiao Chen, Yubei Gu, Duowu Zou

10.5217/ir.2026.00114
View Publication

Real-world data on the effectiveness of risankizumab as induction therapy for ustekinumab-refractory ulcerative colitis

Ryo Morikawa, Toshimitsu Fujii, Akiko Tamura, Ami Kawamoto, Shuji Hibiya, Kento Takenaka, Hiromichi Shimizu, Kazuo Ohtsuka, Ryuichi Okamoto

10.5217/ir.2025.00338
View Publication

Gut microbiome: a key driver and therapeutic target of intestinal fibrosis in Crohn’s disease

Jee Hyun Kim, Yoon Jeong Choi, Jun Hwan Yoo

10.5217/ir.2026.00013
View Publication

Chinese expert consensus on extraintestinal manifestations of inflammatory bowel disease

Jie Liang, Liuqing Zhao, Jun Shen, Hong Yang, Yao He, Ling Liu, Yufang Wang, Kaichun Wu, Minhu Chen

10.5217/ir.2026.00147
View Publication

Upadacitinib in Asian inflammatory bowel disease practice: encouraging real-world efficacy

Eun Soo Kim

10.5217/ir.2026.00200
View Publication

Frequently asked questions

How long does it take to publish?

Initial decision is normally made within 6 weeks on average of receipt of a manuscript. Revised manuscripts must be resubmitted within 8 weeks of the editorial decision. Corresponding authors must respond to manuscript editor revisions within 2 days and report proof errors within 2 days.

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Is a cover letter required?

A cover letter is required. It should state that the submission has not been published previously or is not under consideration elsewhere, disclose potential conflicts of interest, and include preprint posting information and the preprint link when applicable. Authors including minors or family members in the research should indicate this in the cover letter.

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What are the publication costs?

Individual subscription: USD 10 per issue or USD 40 annually; institutional subscription: USD 12 per issue or USD 48 annually.

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Research Topics

Inflammatory Bowel Disease Microscopic Colitis Colorectal Cancer Screening and Detection Gastric Cancer Management and Outcomes Autoimmune and Inflammatory Disorders Gastrointestinal disorders and treatments Clostridium difficile and Clostridium perfringens research Gut microbiota and health Gastrointestinal motility and disorders Diagnosis and treatment of tuberculosis Rheumatoid Arthritis Research and Therapies Diverticular Disease and Complications Gastrointestinal Tumor Research and Treatment Genetic factors in colorectal cancer Gastrointestinal Bleeding Diagnosis and Treatment Colorectal Cancer Surgical Treatments Liver Diseases and Immunity Eosinophilic Esophagitis Helicobacter pylori-related gastroenterology studies Celiac Disease Research and Management Appendicitis Diagnosis and Management Esophageal and GI Pathology Tuberculosis Research and Epidemiology Pregnancy and Medication Impact Biosimilars and Bioanalytical Methods

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