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JAMA Neurology

JAMA Neurology is a specialty journal in the JAMA Network that publishes neurology research and related article categories including Original Investigation, Research Letter, Editorial, Viewpoint, Review, Images in Neurology, and Clinical Challenge.

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Subject Clinical Neurology
Impact Factor 21.3
Quartile Q1
Open Access Type Hybrid
ISSN 2168-6149
eISSN 2168-6157
Invitation Only No
Cost Range $6000 article processing charge for eligible author-pay open access research articles; no fee for the free public access option.

Submission Instructions

JAMA Neurology accepts the following article types. Click on an article type to view submission instructions.

Original Investigation

Cover Letter A cover letter is required.
Abstract A structured abstract is required. The abstract must be structured.
Manuscript Text must not exceed 3000 words. The manuscript must include a study type. The manuscript must include 3 Key Points and a Data Sharing Statement.
References References must follow AMA style. References must be numbered in order of appearance, cited with superscript Arabic numerals, and list up to 6 authors or editors before using the first 3 followed by "et al."
Figures & Tables A maximum of 5 tables and/or figures is allowed. Figures must not be included in the manuscript text and should be submitted as separate files, while tables must be included at the end of the manuscript file rather than uploaded separately. Each table and figure must be numbered, titled, cited in the text, and not duplicate data presented elsewhere.
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Systematic Review (Without Meta-Analysis)

Cover Letter A cover letter is required. The cover letter must state whether the authors have published, posted, or submitted any related papers from the same study.
Abstract A structured abstract is required. The abstract must be structured. The abstract must use the headings Importance, Objective, Evidence Review, Findings, and Conclusions and Relevance.
Manuscript The manuscript must not exceed 3000 words of text. The manuscript must use the subtitle "A Systematic Review" and should include Introduction, Methods, Results, Discussion, and Conclusions sections, with Results generally using the subsections Pathophysiology, Clinical Presentation, Assessment and Diagnosis, Treatment, and Prognosis when appropriate. The manuscript should include 3 Key Points labeled Question, Findings, and Meaning limited to 100 words, and it must include a table with ratings of the quality of the studies or evidence.
References The manuscript must include 50 to 75 references. References must follow AMA style. References must be numbered in order of appearance, cited with superscript arabic numerals, list up to 6 authors or editors before using the first 3 followed by "et al.," and use PubMed journal abbreviations with issue numbers in parentheses after the volume number.
Figures & Tables The manuscript may include no more than 5 tables and/or figures. Figures must be submitted as separate files and not included in the manuscript text, while tables must be included at the end of the manuscript file and not uploaded as separate files. Each table and figure must be numbered, titled, and cited in the text, and the manuscript must include a table with ratings of the quality of the studies or evidence.
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Narrative Review

Cover Letter A cover letter is required.
Abstract A structured abstract is required. Abstract must be no more than 300 words. Abstract must be structured with the headings Importance, Observations, and Conclusions and Relevance. Abstract headings must be Importance, Observations, and Conclusions and Relevance.
Manuscript Manuscript must be 2000 to 3500 words. Manuscript should include an Introduction, optional Methods, Discussion/Observations, and Conclusions, generally with subsections such as Pathophysiology, Clinical Presentation, Assessment and Diagnosis, Treatment, and Prognosis when appropriate, and use the subtitle "A Review." Key Points must not be included.
References References must total 50 to 75. References must follow AMA style. References must be numbered in order of appearance using superscript arabic numerals, not alphabetized, with all authors listed up to 6 and the first 3 followed by "et al" if more than 6.
Figures & Tables No more than 5 tables and/or figures may be included. Figures must not be included in the manuscript text and should be submitted as separate files, while tables must be included at the end of the manuscript file rather than uploaded separately. Narrative Reviews should include tables summarizing epidemiology, diagnostic tools, therapies, and a comparison of review findings with current clinical practice recommendations or diagnostic and therapeutic uncertainty or controversies.
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Brief Report

Cover Letter A cover letter is required.
Abstract A structured abstract is required. The abstract must be structured.
Manuscript The manuscript must be 1200 words. The manuscript must include a study type. The manuscript must include 3 Key Points and a Data Sharing Statement.
References The manuscript may include no more than 15 references. References must follow AMA style. References must be numbered in order of appearance, cited with superscript Arabic numerals, use PubMed journal abbreviations, and list up to 6 authors or editors before using the first 3 followed by "et al.".
Figures & Tables The manuscript may include no more than 3 tables and/or figures. Figures must be submitted as separate files and not embedded in the manuscript text, while tables must be included at the end of the manuscript file and not uploaded separately. Each table and figure must be numbered, titled, and cited in the text, and figures must not have more than 4 panels unless justified.
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Research Letter

Cover Letter A cover letter is required.
Abstract Abstract must not be included.
Manuscript Text must not exceed 800 words. Text should be divided into the sections Introduction, Methods, Results, and Discussion. Key Points must not be included, the manuscript must state the study type, and a Data Sharing Statement is required.
References No more than 10 references may be included. References must follow AMA style. References must be numbered in order of appearance, cited with superscript arabic numerals, and list up to 6 authors or editors, or the first 3 followed by "et al" if there are more than 6.
Figures & Tables No more than 2 small tables and/or figures may be included. Figures must not be included in the manuscript text and tables must be included at the end of the manuscript file rather than uploaded separately.
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Letter To The Editor

Cover Letter A cover letter is required.
Abstract Abstract requirements are not specified.
Manuscript Letter to the Editor text must not exceed 400 words. Letter to the Editor must include the full name, academic degrees, and a single institutional affiliation for each author, plus the corresponding author’s email address.
References Letter to the Editor must include no more than 5 references, including 1 reference to the recent article. References must follow AMA style. References must be numbered in order of appearance using superscript Arabic numerals, not alphabetized, and list up to 6 authors or editors before using the first 3 followed by "et al."
Figures & Tables Figures must not be included in the manuscript text and tables must be included at the end of the manuscript file rather than uploaded separately.
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Recent Publications

Error in Figure

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10.1001/jamaneurol.2026.3783
View Publication

Whole Genomes, Clearer Diagnoses—Precision Care for Children With Neurologic Disease

Terrie E. Inder

10.1001/jamaneurol.2026.3008
View Publication

Rapid Whole-Genome Sequencing in Pediatric Neurology Inpatients

Man Amanat, Asma Ali, Queenie Tan, Paul E. Youssef, Laura Rust, Nicole Boczek, Natasha Strande, Sarah Barnett, Lisa A. Schimmenti, Keith Coffman, Elaine Wirrell, Radhika Dhamija

10.1001/jamaneurol.2026.3410
View Publication

Earlier Disclosure of Blood-Based Biomarkers, Diagnostic Certainty, and Clinical Management

Isabel Estragués-Gázquez, José Contador, Leidy Dayana Martínez, Aida Fernández-Lebrero, Greta García-Escobar, Irene Navalpotro-Gómez, Oriol Grau-Rivera, Gianmarco Iaccarino, Rosa Maria Manero-Borràs, Paula Ortiz-Romero, Felipe Hernández-Villamizar, Javier Torres-Torronteras, Marina de Diego-Osaba, Helena Blasco-Forniés, Esther Jiménez-Moyano, Juan José Hernández, Anna Padrós, Marta del Campo, Albert Puig-Pijoan, Marc Suárez-Calvet

10.1001/jamaneurol.2026.3497
View Publication

Ten Years of Ocrelizumab in Relapsing Multiple Sclerosis

Stephen L. Hauser, Amit Bar-Or, Gavin Giovannoni, Xavier Montalban, Christine Lebrun-Frenay, Lilyana Amezcua, Luisa M. Villar, Douglas L. Arnold, Martin S. Weber, Massimo Filippi, Noemi Pasquarelli, Cathy Chognot, Qing Wang, Hans-Martin Schneble, Licinio Craveiro, Ludwig Kappos

10.1001/jamaneurol.2026.3507
View Publication

Frequently asked questions

How long does it take to publish?

Accepted articles are generally published Online First and then again in a print/online issue.

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Is a cover letter required?

A cover letter is required and should include complete contact information for the corresponding author and whether related papers from the same study have been published, posted, or submitted.

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What are the publication costs?

Research articles may be published under a free no-fee public access option or an author-pay open access option with a $6000 article processing charge.

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Research Topics

Acute Ischemic Stroke Management Intracerebral and Subarachnoid Hemorrhage Research Dementia and Cognitive Impairment Research Parkinson's Disease Mechanisms and Treatments Alzheimer's disease research and treatments Multiple Sclerosis Research Studies Peripheral Neuropathies and Disorders Neurological disorders and treatments Traumatic Brain Injury and Neurovascular Disturbances Epilepsy research and treatment Amyotrophic Lateral Sclerosis Research Genetic Neurodegenerative Diseases Cerebrovascular and Carotid Artery Diseases Stroke Rehabilitation and Recovery Traumatic Brain Injury Research Autoimmune Neurological Disorders and Treatments Health Systems, Economic Evaluations, Quality of Life Pharmacological Effects and Toxicity Studies Intracranial Aneurysms: Treatment and Complications Neurological diseases and metabolism Cardiac Arrest and Resuscitation Neurological and metabolic disorders Neurogenetic and Muscular Disorders Research Neurosurgical Procedures and Complications Genomics and Rare Diseases

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