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npj Aging

npj Aging is part of the npj Series and is published in partnership with the Japan Society of Anti-Aging Medicine. The journal publishes aging research and features articles, reviews, collections, and calls for papers on topics such as mitochondrial function, frailty, Alzheimer’s disease, cancer, senescence, dietary intervention, and age-related diseases.

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Subject Geriatrics & Gerontology
Impact Factor 6
Quartile Q1
Open Access Type Open
eISSN 2731-6068
Invitation Only No
Cost Range Authors pay an article processing charge (APC) for accepted articles; discretionary APC waivers are available.

Submission Instructions

npj Aging accepts the following article types. Click on an article type to view submission instructions.

Article

Cover Letter A cover letter is required with the submission. The cover letter must include the affiliation and contact information for the corresponding author.
Abstract An abstract is required. Abstract must be no more than 150 words. Abstract must be unstructured with no subheadings.
Manuscript Manuscript must include an Introduction with no subheadings, Results and Methods sections with subheadings, a Discussion with no subheadings, and all Methods in the main manuscript rather than the Supplementary Information. Manuscript must include Data availability, Code availability where applicable, Author contributions, and Competing Interests sections, and any use of a Large Language Model must be documented in the Methods or another suitable manuscript section if no Methods section is available.
References References are limited to 60. References must use Nature style. References must be numbered sequentially as they appear, list all authors unless there are more than five in which case the first author is followed by 'et al.', and include only one publication per reference number.
Figures & Tables Figure legends are limited to 350 words per figure. At initial submission, figures should be incorporated into the main article file, but figure files must also be provided individually, and tables must be placed at the end of the text document. Multi-panel figures must be presented on a single page with panels labeled using the a), b), c) convention.
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Review

Cover Letter A cover letter is required. Cover letter should include the affiliation and contact information for the corresponding author.
Abstract An abstract is required. Abstract must be no more than 70 words. Abstract must be unstructured with no subheadings.
Manuscript Main text is typically 3,000–4,000 words in length. Subheadings are permitted in the main text. An Author contributions statement and a Competing Interests statement are mandatory, and any use of a Large Language Model must be documented in the Methods section or another suitable part of the manuscript if no Methods section is available.
References References are limited to 60. References must use standard Nature referencing style. References must be numbered sequentially as they appear, with all authors listed unless there are more than five authors, in which case the first author should be followed by 'et al.'.
Figures & Tables At initial submission, figures should be incorporated into the main article file, figure legends must appear in the main manuscript after the references, and tables must be submitted at the end of the text document. Figure legends are limited to 350 words per figure, multi-panel figures must be presented on a single page, and each panel must be labeled using an a), b), c) convention.
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Brief Communication

Cover Letter A cover letter is required. The cover letter should include the affiliation and contact information for the corresponding author.
Abstract An abstract is required. Abstract must be up to 70 words. Abstract must be unstructured with no subheadings.
Manuscript Main text should be 1,000-1,500 words, excluding the abstract, methods, references, and figure legends. Main text must have no subheadings, while the Methods section must use subheadings and be provided in the main manuscript file rather than the Supplementary Information. The manuscript must include Data availability, Code availability where applicable, Author contributions, and Competing Interests sections, and any use of a Large Language Model must be documented in the Methods section or a suitable alternative section if no Methods section is available.
References References should be around 20. References must use standard Nature referencing style. References must be numbered sequentially in order of appearance, with all authors listed unless there are more than five, in which case the first author should be followed by 'et al.'.
Figures & Tables At initial submission, figures should be incorporated into the main article file, while figure files must also be provided individually if they cannot be clearly incorporated, and tables must be submitted at the end of the text document. Figure legends are limited to 350 words per figure, multi-panel figures must be presented on a single page, and each panel must be labeled using an a), b), c) convention.
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Recent Publications

Cancer burden among adults aged 65 years and older in Asia, 1990–2023: a systematic analysis of the Global Burden of Disease Study 2023

Tianjiao Zhou, Enhui Zhou, Wen Lu, Jianyin Zou, Jingyu Zhang, Chenyang Li, Hangdong Shen, Chen Xu, Ying Shen, Jianxiang Li, Huaming Zhu, Chuan Xu, Hongliang Yi, Shankai Yin, Weijun Huang

10.1038/s41514-026-00419-0
View Publication

Methylglyoxal engages aging-associated mechanisms to cause filtration impairment in nephrocytes

Lie Cheng, Wan-Ju Yeh, Fan-Chi Chang, Hong-Wen Tang, Chih-Chiang Chan, Shuei-Liong Lin, Shu-Yi Huang

10.1038/s41514-026-00369-7
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Targeting mitophagy for neuroprotection: mechanisms and therapeutic opportunities

Jiahui Yang, Jianfeng Li, Xintong Hou, Yifei Zheng, Zeyu Zhao, Ting Zhou, Tongwei Jing, Jiming Kong, Guohui Zhang, Ying Guo

10.1038/s41514-026-00424-3
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Peripheral immunosenescence biomarkers and longitudinal cognitive decline: a large population-based study

Rong Hua, Aimin Yang, Chun Sing Lam, Yuanyuan Wang, Chenglong Li

10.1038/s41514-026-00423-4
View Publication

Author Correction: MicroRNA profiles in plasma-derived extracellular vesicles across the human lifespan

C. Ráez-Meseguer, C. Navas-Enamorado, X. Capó, AM Galmes-Panades, A. Molina de la Llave, M. Mendez-Varela, M. Martinez-Calvo, A. Bennasar-Arbos, A. Sánchez-Polo, L. Masmiquel, M. Torrens-Mas, M. Monjo, JM Ramis, M. Gonzalez-Freire

10.1038/s41514-026-00406-5
View Publication

Frequently asked questions

How long does it take to publish?

Median time from submission to first editorial decision is 15 days. Median time from submission to acceptance is 116 days.

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Is a cover letter required?

A cover letter should be provided and should include the affiliation and contact information for the corresponding author, the context and importance of the work, why it is appropriate for the journal, confidential information such as conflicts of interest, any related work in press or submitted elsewhere, and optional suggested or excluded referees.

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What are the publication costs?

Authors pay an article processing charge (APC) for accepted articles; discretionary APC waivers are available.

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Research Topics

Genetics, Aging, and Longevity in Model Organisms Telomeres, Telomerase, and Senescence Frailty in Older Adults Epigenetics and DNA Methylation Dementia and Cognitive Impairment Research Neuroinflammation and Neurodegeneration Mechanisms Nutrition and Health in Aging Functional Brain Connectivity Studies Nutritional Studies and Diet Diet and metabolism studies Muscle Physiology and Disorders Single-cell and spatial transcriptomics Health, Environment, Cognitive Aging Tryptophan and brain disorders Alzheimer's disease research and treatments Mitochondrial Function and Pathology Adipose Tissue and Metabolism MicroRNA in disease regulation Circadian rhythm and melatonin Sirtuins and Resveratrol in Medicine Immune cells in cancer Neural and Behavioral Psychology Studies Gut microbiota and health Balance, Gait, and Falls Prevention Autophagy in Disease and Therapy

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