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Pharmacological Research

Pharmacological Research is an IUPHAR-affiliated journal that publishes cutting-edge articles in biomedical sciences across molecular, biochemical, translational, and clinical pharmacology, including clinical trials. The journal covers a broad range of topics spanning cardiovascular research, neuroscience, oncology, immunology, renal pharmacology, pregnancy-related pharmacology, pharmacogenomics, natural products, rare diseases, and related pharmacological fields, with invited and unsolicited review articles welcome.

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Impact Factor 10.5
Quartile Q1
Open Access Type Open
ISSN 1043-6618
eISSN 1096-1186
Invitation Only No
Cost Range Article Publishing Charge: USD 4510 excluding taxes for all articles.

Submission Instructions

Pharmacological Research accepts the following article types. Click on an article type to view submission instructions.

Original Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Manuscript must be divided into clearly defined and numbered sections, with the abstract excluded from section numbering. Manuscript must include 1 to 7 English keywords, 3 to 5 highlights submitted as a separate editable file, a graphical abstract submitted as a separate file, and if generative AI was used in writing, a declaration section placed immediately before the references.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order of appearance and may use any consistent style as long as author names, source title details, year, and volume or pagination information are included where applicable.
Figures & Tables Figures must be uploaded as separate files, while tables must be provided as editable text. All figures and tables must be cited in the text, numbered consecutively in order of appearance, and provided with captions.
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Review Articles

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Manuscript must be divided into clearly defined and numbered sections, with the abstract excluded from section numbering. Manuscript must specify the paper type in the heading, include 1 to 7 keywords, provide highlights as a separate editable file with 3 to 5 bullet points, include a graphical abstract at submission as a separate file, and add a declaration section before the references if generative AI was used in manuscript preparation.
References References must be cited in the text using numbers in square brackets. References must be numbered in the order of appearance, be consistent in style, include core bibliographic details, and use LTWA journal title abbreviations.
Figures & Tables Tables must be submitted as editable text, while figures and other graphical items must be uploaded as separate files and all must be cited in the manuscript text. Tables must be numbered consecutively and include captions, and figures must be numbered by order of appearance and include captions.
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Meta-Analyses

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Manuscript must be divided into clearly defined and numbered sections, and the heading must specify the paper type. Provide 1 to 7 keywords, submit 3 to 5 highlights as a separate editable file, provide a graphical abstract at submission, and include a declaration of generative AI use at the end of the manuscript before the references if such tools were used in writing.
References References must be cited in the text using numbers in square brackets. References may be in any consistent style, must be numbered in order of appearance, and should include standard bibliographic details with journal titles abbreviated according to LTWA.
Figures & Tables Tables must be provided as editable text, while figures and other graphical media must be uploaded as separate files with the manuscript. Tables and figures must be cited in the text, numbered consecutively in order of appearance, and accompanied by captions.
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Letters To The Editor

Cover Letter Cover Letter requirements are not specified.
Abstract Abstract must not exceed 250 words.
Manuscript Manuscript must identify the paper type in the heading and Letters To The Editor must address relevant issues of pharmacology or comment on the published literature. Manuscript must include 1 to 7 keywords in English, and if generative AI was used in manuscript preparation, a declaration section must be added immediately before the references.
References References must be cited in the text using numbers in square brackets and listed in the order they appear, with a consistent style containing the required bibliographic details.
Figures & Tables Tables and figures must be uploaded as separate files rather than embedded only in the manuscript. Tables must be editable text with captions and figures must each have a caption and be cited in the manuscript text.
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Recent Publications

Non-coding RNA regulatory networks in post-stroke neuropsychiatric complications: Mechanisms, delivery strategies, and translational challenges

Dekai Wei, Tianbao Wang, Xiaoxiao Song, X.U. Yuxin, Yanqiu You, Yufei Wei

10.1016/j.phrs.2026.108263
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Sphingolipid Metabolism Meets Natural Bioactives: A New Perspective on Metabolic Disease Intervention

Yingrui He, Jian Tan, Jinxin Liu, Rongzhen Zhong, Linshu Jiang, Yuchao Zhao

10.1016/j.phrs.2026.108288
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Mitochondrial vulnerability to aldehydic load and the role mitochondrial aldehyde dehydrogenases.

Takuya Seike, Daria Mochly-Rosen

10.1016/j.phrs.2026.108285
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Receptor-Interacting Protein Kinases (RIPK1–RIPK4) in Cardiac Pathophysiology: Mechanistic Signaling, Disease Contexts, and Emerging Pharmacological Targets

Basma Refai Ali Mohamed, Mengdie Wang, Jiafeng Xie, Abdallah Iddy Chaurembo, Xinyu Chen, Yi Wang, Na Xing, Han-Bin Lin

10.1016/j.phrs.2026.108287
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IUPHAR review. Gut Microbial Metabolites as Remote Regulators of Behavior and Neuropsychiatric Disease

Liang Hao, Zi-Fei Li, Ya-Na Qu, Fu-Ying Zhao, Shi-Yang Lu, Bai-Qiang Li, Hai-Yang Zhang, Hua-Qin Wang

10.1016/j.phrs.2026.108284
View Publication

Frequently asked questions

How long does it take to publish?

1 day submission to first decision; 31 days submission to decision after review; 73 days submission to acceptance; 2 days acceptance to online publication.

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What are the publication costs?

Article Publishing Charge: USD 4510 excluding taxes for all articles.

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Research Topics

Neuroscience and Neuropharmacology Research Receptor Mechanisms and Signaling Neuropeptides and Animal Physiology Nitric Oxide and Endothelin Effects Neurotransmitter Receptor Influence on Behavior Ion channel regulation and function Diverse Scientific and Economic Studies Human auditory perception and evaluation Eicosanoids and Hypertension Pharmacology Educational Robotics and Engineering Adipose Tissue and Metabolism Drug Transport and Resistance Mechanisms Pain Mechanisms and Treatments Diet and metabolism studies Cardiac electrophysiology and arrhythmias Gut microbiota and health Tryptophan and brain disorders Adenosine and Purinergic Signaling Cannabis and Cannabinoid Research Cardiac Ischemia and Reperfusion Stress Responses and Cortisol Mitochondrial Function and Pathology Inflammatory mediators and NSAID effects Pharmacological Receptor Mechanisms and Effects Autophagy in Disease and Therapy