WJ

World Journal Of Gastroenterology

World Journal of Gastroenterology is a rigorously peer-reviewed, open-access academic journal dedicated to publishing original, high-quality research findings in gastroenterology, hepatology, gastrointestinal oncology, gastrointestinal endoscopy, gastrointestinal surgery, epidemiology, genetics, imaging, immunology, pathology, pathophysiology, nutrition, and nursing, including clinical, translational, and basic studies, as well as research involving artificial intelligence. It publishes clinical study, basic study, case report, editorial, review, minireview, systematic review, meta-analysis, guidelines, and correspondence.

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Impact Factor 5.4
Quartile Q1
Open Access Type Open
ISSN 1007-9327
eISSN 2219-2840
Invitation Only No
Cost Range Article Processing Charge information is provided via a separate APC page.

Submission Instructions

World Journal Of Gastroenterology accepts the following article types. Click on an article type to view submission instructions.

Review

Cover Letter A cover letter is required. Cover letter should include a concise introductory statement, relevant contextual information, suggested reviewers with contact details, reasons for any deviations from standard format, and clarification of potential conflicts related to the exclusive nature of the publication.
Abstract An abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript may contain up to 6,000 words. Abstract must contain the essential components of each manuscript section in IMRaD format. The manuscript must include 3-4 keywords and a declaration of generative AI and AI-assisted technologies in the writing process placed before the references if such tools were used in writing.
References References are limited to 150. References must use superscripted Arabic numerals in order of appearance. References must be accurate, closely related to the text, cited in correct numerical order, and use Index Medicus abbreviations.
Figures & Tables Up to 6 tables and figures are allowed. The main text, tables, and figures must be embedded in a single manuscript file, although tables may also be uploaded separately and figures must be submitted as separate attachments. Figures and tables must be necessary and clear, numbered consecutively in text order, avoid duplicating manuscript content, and figure legends should be included at the end of the manuscript body.
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Basic Study

Cover Letter A cover letter is required. Cover letter should include a concise introductory statement, suggested two to five reviewers with email addresses and phone number, reasons for any deviations from standard format, and clarification of potential conflicts related to the exclusive nature of the publication.
Abstract An abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript should follow IMRaD, with the abstract containing the essential components of each manuscript section and the Materials and Methods section included within the main text rather than supplemental material. Manuscript must include 3-4 keywords in the abstract and, if generative AI or AI-assisted technologies were used in writing, a section before the References entitled 'Declaration of Generative AI and AI-assisted technologies in the writing process'.
References References must be cited using superscripted Arabic numerals in order of appearance. References must be closely related to the text, cited in correct numerical order, and journal abbreviations should follow Index Medicus abbreviations.
Figures & Tables The main text, tables, and figures must be embedded in a single manuscript file, while tables may either be uploaded separately or included at the end of the manuscript document and figures must also be submitted as separate attachments. Figures and tables must follow principles of necessity and clarity, avoid duplicating manuscript text, be numbered consecutively in order of appearance, and figure legends should be included at the end of the manuscript body.
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Retrospective Study

Cover Letter Cover letter is required. Cover letter should include a concise introductory statement, relevant contextual information, suggested two to five reviewers with email addresses and phone number, reasons for any deviations from standard format, and clarification of potential conflicts related to exclusive publication.
Abstract Abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript should follow an IMRaD structure, with the abstract containing the essential components of each manuscript section and the Materials and Methods section included within the main text. Manuscript must include 3-4 keywords and a section entitled 'Declaration of Generative AI and AI-assisted technologies in the writing process' before the references if such tools were used in writing.
References References must be cited with superscripted Arabic numerals in order of appearance in the text and journal abbreviations should follow Index Medicus.
Figures & Tables The main text, tables, and figures must be embedded in a single manuscript file, although tables may either be uploaded separately or included at the end of the manuscript document and figures must be submitted as separate attachments. Figures and tables must be necessary, clear, non-duplicative of the text, and numbered consecutively in the order of appearance, with figure legends included at the end of the manuscript body.
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Case Control Study

Cover Letter A cover letter is required. Cover letter should include a concise introductory statement, two to five suggested reviewers with email addresses and phone number, reasons for any deviations from standard format, and clarification of potential conflicts related to exclusive publication.
Abstract An abstract is required. Abstract must not exceed 260 words. Abstract must be structured and contain the essential components of each manuscript section in IMRaD form. Structured abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript must include a Materials and Methods section within the main text. Manuscript must include 3-4 keywords, a Data Transparency Statement on the title page, and a 'Declaration of Generative AI and AI-assisted technologies in the writing process' section before the references if such tools were used in writing.
References References must be cited in the text as superscript Arabic numerals in order of appearance and use Index Medicus abbreviations.
Figures & Tables The main text, tables, and figures must be embedded in a single manuscript file, while tables may also be uploaded separately or included at the end of the manuscript document and figures must be submitted as separate attachments. Figures and tables must be numbered consecutively in the order cited, figure legends must appear at the end of the manuscript body, and multiple-panel figures must be submitted as a single attachment.
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Observational Study

Cover Letter A cover letter is required. Cover letter should include a concise introductory statement, relevant contextual information, two to five suggested reviewers with email addresses and phone number, reasons for any deviations from standard format, and clarification of potential conflicts related to the exclusive nature of the publication.
Abstract An abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript should follow IMRaD, and the Materials and Methods section must be included within the main text rather than in supplemental files. The manuscript must include 3-4 keywords and, if generative AI or AI-assisted technologies were used in writing, a section titled 'Declaration of Generative AI and AI-assisted technologies in the writing process' before the References list.
References References must use superscripted Arabic numerals in order of appearance. References must be closely related to the text, cited in correct numerical order, and journal abbreviations should follow Index Medicus.
Figures & Tables The main text, tables, and figures must be embedded in a single manuscript file, although tables may either be uploaded separately or included at the end of the manuscript document, and figures must also be submitted as separate attachments. Figures and tables must avoid duplicate content, be numbered consecutively in the order cited, figure legends must appear at the end of the manuscript body, and multiple-panel figures must be submitted as a single attachment.
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Retrospective Cohort Study

Cover Letter Cover letter is required and should include a concise introductory statement, relevant contextual information, suggested reviewers with contact details, reasons for any deviations from standard format, and clarification of potential publication-related conflicts. Cover letter should include a concise introductory statement describing the manuscript, relevant contextual information, two to five suggested reviewers with email addresses and phone number, reasons for deviations from standard format, and clarification of potential conflicts related to the exclusive nature of the publication.
Abstract Abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript should follow IMRaD structure, with the abstract containing the essential components of each manuscript section and the Materials and Methods section included within the main text. Manuscript should include 3-4 keywords separated by semicolons and a declaration section before the References entitled 'Declaration of Generative AI and AI-assisted technologies in the writing process' if such tools were used in writing.
References References must use superscripted Arabic numerals in order of appearance. References must be cited in correct numerical order, be closely related to the subject matter, use Index Medicus abbreviations, and personal communications or unpublished data should be cited directly in the text without numbering.
Figures & Tables Main text, tables, and figures must be embedded in a single manuscript file uploaded at one time, although tables may alternatively be uploaded separately and figures must be submitted as separate attachments. Figures and tables must be necessary and clear, numbered consecutively in order of appearance, avoid duplication with the text, include figure legends at the end of the manuscript body, and multiple-panel figures must be submitted as a single attachment.
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Clinical Trials Study

Cover Letter Cover Letter requirements are not specified.
Abstract A structured abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract must be organized as Background and Aims, Methods, Results, Conclusions, and Keywords, and the clinical trial registry website and trial number must be provided at the end of the Conclusions section.
Manuscript Manuscript must include a Methods section containing a statement that all authors had access to the study data and reviewed and approved the final manuscript. Manuscript must include 3-4 keywords in the abstract, a Data Sharing Statement on the title page under the heading 'Data Transparency Statement,' and a declaration of generative AI and AI-assisted technologies in the writing process before the References list if such tools were used.
References References must use superscripted Arabic numerals in order of appearance. References must be cited in correct numerical order, personal communications and unpublished data must be cited only in the text without numbering, and journal abbreviations must follow Index Medicus.
Figures & Tables A CONSORT patient flowchart must be included as one of the figures in the manuscript. Tables may be uploaded separately or included at the end of the manuscript document, figure legends must appear at the end of the manuscript body, and figures must be submitted as separate attachments. Figures and tables must avoid duplicate content with the text, be numbered consecutively in order of appearance, and multiple-panel figures must be submitted as a single attachment.
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Prospective Study

Cover Letter Cover letter is required. Cover letter should include a concise introductory statement, suggested reviewers with contact details, reasons for any deviations from standard format, and clarification of potential conflicts related to exclusive publication.
Abstract Abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript should follow an IMRaD structure, and the Materials and Methods section must be included within the main text rather than in supplemental material. Manuscript must include 3-4 keywords and, if generative AI or AI-assisted writing tools were used, a declaration section titled 'Declaration of Generative AI and AI-assisted technologies in the writing process' placed before the references.
References References must be cited with superscript Arabic numerals in order of appearance in the text and use Index Medicus abbreviations.
Figures & Tables The main text, tables, and figures must be embedded in a single manuscript file, although tables may be uploaded separately or included at the end of the manuscript document, and figures must be submitted as separate attachments with legends placed at the end of the manuscript body. Figures and tables must avoid duplicate content, be numbered consecutively in the order cited, and multiple-panel figures must be submitted as a single attachment containing all panels.
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Randomized Controlled Trial

Cover Letter A cover letter is required. Cover letter should include a concise introduction to the manuscript, relevant contextual information, suggested reviewers with contact details, reasons for any deviations from standard format, and clarification of potential conflicts related to exclusive publication.
Abstract An abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords, and the clinical trial registry website and trial number must be provided at the end of the Conclusions section.
Manuscript Manuscript should follow IMRaD, include a Methods section within the main text, and the Methods section must state that all authors had access to the study data and reviewed and approved the final manuscript. Manuscript must include 3-4 keywords, a title page with a Data Sharing Statement under the heading 'Data Transparency Statement', a Declaration of Generative AI and AI-assisted technologies in the writing process before the references if such tools were used, and a CONSORT patient flowchart as one of the figures.
References References must be cited using superscript Arabic numerals in order of appearance. References must be closely related to the subject matter, cited in correct numerical order, and journal abbreviations should follow Index Medicus.
Figures & Tables Main text, tables, and figures must be embedded in a single manuscript file, figures must also be submitted as separate attachments, tables may be uploaded separately or included at the end of the manuscript, figure legends should appear at the end of the manuscript body, and the CONSORT patient flowchart must be included as one figure. Figures and tables must be necessary, clear, non-duplicative with the text, and numbered consecutively in order of appearance.
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Randomized Clinical Trial

Cover Letter Cover Letter requirements are not specified.
Abstract An abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract must be organized as Background and Aims, Methods, Results, Conclusions, and Keywords, and the clinical trial registry website and trial number must be provided at the end of the Conclusions section.
Manuscript Manuscript must include a Methods section containing a statement that all authors had access to the study data and reviewed and approved the final manuscript. Manuscript must include 3-4 keywords separated by semicolons and a Declaration of Generative AI and AI-assisted technologies in the writing process before the References list if such tools were used.
References References must be cited with superscript Arabic numerals in order of appearance in the text and use Index Medicus abbreviations.
Figures & Tables The main text, tables, and figures must be embedded in a single manuscript file, tables may either be uploaded separately or included at the end of the manuscript document, and figures must be submitted as separate attachments. Figure legends must be included at the end of the manuscript body, figures and tables must be numbered consecutively in order of appearance, and a CONSORT patient flowchart must be included as one of the figures.
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Systematic Review

Cover Letter A cover letter should be included with the submission. The cover letter should briefly describe the manuscript, may suggest two to five reviewers with contact details, should explain any deviations from standard format, and should clarify potential conflicts related to exclusive publication.
Abstract An abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript The abstract should reflect the essential components of the manuscript in IMRaD format, and the Materials and Methods section and references cited in the main text must remain within the main text rather than supplemental files. The manuscript must include 3–4 keywords, and any use of generative AI or AI-assisted technologies in writing must be disclosed in a section titled 'Declaration of Generative AI and AI-assisted technologies in the writing process' placed before the References list.
References References must use superscript Arabic numerals in order of appearance. References must be accurate, closely related to the text, cited in correct order, and journal abbreviations should follow Index Medicus.
Figures & Tables A PRISMA flow chart must be included as one of the figures. The main text, tables, and figures must be embedded in a single manuscript file, although tables may alternatively be uploaded separately and figures must also be submitted as separate attachments. Figures and tables must be necessary and clear, numbered consecutively, and should not duplicate content presented elsewhere in the manuscript.
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Meta-Analysis

Cover Letter Cover letter is required. Cover letter should include a concise introductory statement, relevant contextual information, suggested reviewers with contact details, reasons for any deviations from standard format, and clarification of potential conflicts related to the exclusive nature of the publication.
Abstract Abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript should follow IMRaD, with the abstract containing the essential components of each manuscript section and the Materials and Methods section included within the main text rather than supplemental files. Manuscript must include 3-4 keywords and, if generative AI or AI-assisted technologies were used in writing, a declaration section titled 'Declaration of Generative AI and AI-assisted technologies in the writing process' before the References list.
References References must be cited with superscript Arabic numerals in order of appearance in the text and use Index Medicus abbreviations.
Figures & Tables The main text, tables, and figures must be embedded in a single manuscript file, while figures must also be submitted as separate attachments and tables may either be uploaded separately or included at the end of the manuscript document. Figures and tables must avoid duplicate content, be numbered consecutively in order of appearance, and figure legends should be included at the end of the manuscript body.
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Original Articles

Cover Letter Cover letter is required. Cover letter should include a concise introductory statement, two to five suggested reviewers with email addresses and phone number, reasons for any deviations from standard format, and clarification of potential conflicts related to the exclusive nature of the publication.
Abstract Abstract is required. Abstract must be 260 words. Abstract must be structured. Abstract must use the headings Background and Aims, Methods, Results, Conclusion, and include 4-5 keywords.
Manuscript Manuscript must not exceed 7,000 words inclusive of main text, references, and table/figure legends. Manuscript must place Materials and Methods immediately after the Introduction. Manuscript must include a 'What You Need to Know' box with the headings BACKGROUND AND CONTEXT, NEW FINDINGS, LIMITATIONS, CLINICAL RESEARCH RELEVANCE, and BASIC RESEARCH RELEVANCE, a lay summary of 25-30 words, and a 'Declaration of Generative AI and AI-assisted technologies in the writing process' section before the References list if such tools were used.
References References must be cited in superscripted Arabic numerals in order of appearance, include underlying or relevant datasets as data references when applicable, list names of authors who share first authorship in bold text, and end with the phrase 'Author names in bold designate shared co-first authorship'.
Figures & Tables Manuscript may include a total of seven tables and/or figures, and tables alone are limited to seven. Tables may be uploaded separately or included at the end of the manuscript document, while figures must be submitted as separate attachments. Tables may not contain panels, and figures must be submitted in JPEG, TIFF, EPS, or PDF format at 300 PPI resolution.
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Reviews In Basic And Clinical Gastroenterology And Hepatology

Cover Letter A cover letter is required. Cover letter should include a concise introductory statement, relevant contextual information, suggested two to five reviewers with email addresses and phone number, reasons for any deviations from standard format, and clarification of potential conflicts related to the exclusive nature of the publication.
Abstract An abstract is required. Abstract must not exceed 260 words. Abstract must be structured. Abstract should be organized as Background and Aims, Methods, Results, Conclusions, and Keywords.
Manuscript Manuscript may contain up to 6,000 words. Manuscript should follow IMRaD components in the abstract, and the Materials and Methods section must be included within the main text rather than as supplemental information. Manuscript must include 3-4 keywords separated by semicolons and a declaration section entitled 'Declaration of Generative AI and AI-assisted technologies in the writing process' before the references if such tools were used.
References References are limited to 150. References must be cited using superscripted Arabic numerals in order of appearance. References must be listed in the order of appearance, use Index Medicus abbreviations, and personal communications or unpublished data should be cited only in the text without numbering.
Figures & Tables A maximum of 6 tables and figures is allowed. Tables may be uploaded separately or included at the end of the manuscript document, while figures must be submitted as separate attachments and figure legends should be included at the end of the manuscript body. Figures and tables must avoid duplicate content, be numbered consecutively in the order cited, and multiple-panel figures must be submitted with all panels together in a single attachment.
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Full Length Original Research

Cover Letter A cover letter is required. Cover letter should include a concise introductory statement, relevant contextual information, suggested two to five reviewers with email addresses and phone number, reasons for any deviations from standard format, and clarification of potential conflicts related to exclusive publication.
Abstract A structured abstract is required. Abstract must be 260 words. Abstract must be structured. Abstract must use the headings Background and Aims, Methods, Results, Conclusion, and include 4-5 keywords.
Manuscript Manuscript must not exceed 7,000 words inclusive of main text, references, and table/figure legends. Materials and Methods must be placed immediately after the Introduction. Manuscript must include a 'What You Need to Know' box with the headings BACKGROUND AND CONTEXT, NEW FINDINGS, LIMITATIONS, CLINICAL RESEARCH RELEVANCE, and BASIC RESEARCH RELEVANCE, a 25-30-word lay summary, and a declaration of generative AI and AI-assisted technologies in the writing process before the References list if such tools were used.
References References must be cited using superscripted Arabic numerals in order of appearance. References must follow order of appearance, include underlying or relevant datasets as data references when cited, list names of authors who share first authorship in bold text, and end with the phrase 'Author names in bold designate shared co-first authorship'.
Figures & Tables Manuscript may include a total of seven tables and/or figures, and tables alone are limited to seven. Tables may be uploaded separately or included at the end of the manuscript document, while figures must be submitted as separate attachments. Tables may not contain panels, and figures must be submitted as separate JPEG, TIFF, EPS, or PDF files at 300 PPI resolution.
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Recent Publications

Growth arrest specific 6 ameliorated inflammation and portal pressure through activating efferocytosis in cholestasis and portal hypertension

Gu-Qing Luo, Jin-Bo Zhao, Zheng-Hao Wu, Jia-Yun Lin, Chi-Hao Zhang, Guang-Bo Wu, Qiang Fan, Xiao-Liang Qi, Hong-Jie Li, Meng Luo, Lei Zheng

10.3748/wjg.v32.i20.116020
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Optimizing branch-duct intraductal papillary mucinous neoplasms surveillance: Data-driven dimensional grouping for risk stratification and cost-effectiveness

Stefano Kayali, Simone Dibitetto, Alberto Busatto, Federica Gaiani, Andrea Pasta, Francesco Calabrese, Stefano Fantasia, Simone Caprioli, Andrea P Luzzi, Claudio G De Angelis, Edoardo V Savarino, Luigi Laghi, Edoardo G Giannini, Elisa Marabotto

10.3748/wjg.v32.i20.114867
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Gastric microenvironment and gastric cancer: Interplay of acid, microbiota, and inflammation

Hao-Cheng Zheng, Ting Zhou, Lei Sun, Xia Ding

10.3748/wjg.v32.i20.117044
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Textbook oncologic outcomes following pancreatoduodenectomy in patients with pancreatic adenocarcinoma: A high-volume center study

Jing-Zhao Zhang, Xin-Yi Guo, Zhi-Wei Zhang, Deng-Sheng Zhu, Zhen Zhang, Huan Zheng, Tong Guo, Ya-Hong Yu, Xiao-Rui Huang

10.3748/wjg.v32.i20.119062
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Therapeutic effects of rhubarb enema on Th17 cell and systemic inflammatory response in clinical acute pancreatitis

Lin-Gui Zhong, Yu Luo, Fang Gao, Ting-Ting Guo, Jian Yang, Chuan-Jiang Wang

10.3748/wjg.v32.i20.116036
View Publication

Frequently asked questions

How long does it take to publish?

Duration of peer review: 24 days mean; days from submission to first decision: 41 days mean; second decision time: 37 days mean; production time: 56 days mean; time to publication: 177 days mean.

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Is a cover letter required?

A cover letter is expected and is checked during initial screening for alignment with the journal and manuscript content.

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What are the publication costs?

Article Processing Charge information is provided via a separate APC page.

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Research Topics

Liver Disease Diagnosis and Treatment Helicobacter pylori-related gastroenterology studies Gastric Cancer Management and Outcomes Liver Disease and Transplantation Pancreatic and Hepatic Oncology Research Hepatitis B Virus Studies Hepatitis C virus research Hepatocellular Carcinoma Treatment and Prognosis Inflammatory Bowel Disease Pancreatitis Pathology and Treatment Gastrointestinal disorders and treatments Gallbladder and Bile Duct Disorders Gastroesophageal reflux and treatments Esophageal and GI Pathology Gastrointestinal Tumor Research and Treatment Cholangiocarcinoma and Gallbladder Cancer Studies Organ Transplantation Techniques and Outcomes Microscopic Colitis Gastrointestinal motility and disorders Colorectal Cancer Screening and Detection Pediatric Hepatobiliary Diseases and Treatments Liver physiology and pathology Eosinophilic Esophagitis Genetic factors in colorectal cancer Esophageal Cancer Research and Treatment